Role of n-3 Polyunsaturated Fatty Acids and Exercise in Breast Cancer Prevention: Identifying Common Targets

Diet and exercise are recognized as important lifestyle factors that significantly influence breast cancer risk. In particular, dietary n-3 polyunsaturated fatty acids (PUFAs) have been shown to play an important role in breast cancer prevention. Growing evidence also demonstrates a role for exercise in cancer and chronic disease prevention. However, the potential synergistic effect of n-3 PUFA intake and exercise is yet to be determined. This review explores targets for breast cancer prevention that are common between n-3 PUFA intake and exercise and that may be important study outcomes for future research investigating the combined effect of n-3 PUFA intake and exercise. These lines of evidence highlight potential new avenues for research and strategies for breast cancer prevention.

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The Role of Omega-3 Fatty Acids in Breast Cancer Prevention

Trends in Breast Cancer Prevention ◽

10.1007/978-3-319-27135-4_3 ◽

2016 ◽

pp. 51-81

Author(s):

Andrea Manni ◽

Karam El-Bayoumy ◽

Christine G. Skibinski ◽

Henry J. Thompson ◽

Julia Santucci-Pereira ◽

...

Keyword(s):

Breast Cancer ◽

Fatty Acids ◽

Cancer Prevention ◽

Breast Cancer Prevention ◽

Omega 3 Fatty Acids ◽

Omega 3

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Learning from and Leveraging Multi-Level Changes in Responses to the COVID 19 Pandemic to Facilitate Breast Cancer Prevention Efforts

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18136999 ◽

2021 ◽

Vol 18 (13) ◽

pp. 6999

Author(s):

Deborah J. Bowen ◽

Kelly E. Rentscher ◽

Amy Wu ◽

Gwen Darien ◽

Helen Ghirmai Haile ◽

...

Keyword(s):

Breast Cancer ◽

Health Care ◽

Cancer Prevention ◽

Care Delivery ◽

Breast Cancer Prevention ◽

Health Care Use ◽

Economic Life ◽

Future Research ◽

Multi Level ◽

And Shifts

The coronavirus pandemic (COVID-19) has had multilevel effects on non-COVID-19 health and health care, including deferral of routine cancer prevention and screening and delays in surgical and other procedures. Health and health care use has also been affected by pandemic-related loss of employer-based health insurance, food and housing disruptions, and heightened stress, sleep disruptions and social isolation. These disruptions are projected to contribute to excess non-COVID-19 deaths over the coming decades. At the same time municipalities, health systems and individuals are making changes in response to the pandemic, including modifications in the environmental to promote health, implementation of telehealth platforms, and shifts towards greater self-care and using remote platforms to maintain social connections. We used a multi-level biopsychosocial model to examine the available literature on the relationship between COVID-19-related changes and breast cancer prevention to identify current gaps in knowledge and identify potential opportunities for future research. We found that COVID-19 has impacted several aspects of social and economic life, through a variety of mechanisms, including unemployment, changes in health care delivery, changes in eating and activity, and changes in mental health. Some of these changes should be reduced, while others should be explored and enhanced.

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The Role of Flavonoids in Fruits and Vegetables Related to Breast Cancer Prevention

Bioactive Foods and Extracts ◽

10.1201/b10330-31 ◽

2010 ◽

pp. 399-412

Keyword(s):

Breast Cancer ◽

Cancer Prevention ◽

Fruits And Vegetables ◽

Breast Cancer Prevention

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Mammary stem cells: the root of breast cancer?

Breast Cancer Online ◽

10.1017/s1470903104001324 ◽

2004 ◽

Vol 7 (9) ◽

Cited By ~ 2

Author(s):

H. A. Coppock ◽

R. B. Clarke

Keyword(s):

Breast Cancer ◽

Stem Cells ◽

Mammary Gland ◽

Cancer Prevention ◽

Breast Cancer Prevention ◽

Differentiated Cells ◽

Mammary Stem ◽

Tissue Specific Stem Cells ◽

Prevention And Therapy

Tissue-specific stem cells play a key role in organ homoeostasis. They are relatively well characterized in systems which undergo constant proliferation and production of differentiated cells, including the haemopoietic system, skin and intestine. However, little is known about the role and regulation of stem cells in the mammary gland. This review briefly summarizes the current understanding of the role of breast-specific stem cells in normal and cancerous tissues, and how this may identify new targets for breast cancer prevention and therapy.

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