scholarly journals Effects of low and high deprenyl dose on antioxidant enzyme activities in the adult rat brain

2017 ◽  
Vol 36 (01) ◽  
pp. 83-90 ◽  
Author(s):  
Maria Lalkovicova ◽  
Frantiska Horvathova ◽  
Igor Sulla ◽  
Jozef Mihalik ◽  
Viera Danielisova
2001 ◽  
Vol 56 (9-10) ◽  
pp. 912-914 ◽  
Author(s):  
Stylianos Tsakiris ◽  
Christos Koromilas ◽  
Kleopatra H. Schulpis

Abstract The effects of different a-D-Glucose (Glu) concentrations (0 -16 mᴍ) on Na+, K+-ATPase and Mg2+-ATPase activities were investigated in homogenates of adult male rat whole brain at 37 °C. The enzyme activities were determined after 1h preincubation with Glu. Brain Na+, K+-ATPase was not affected by Glu different concentrations. On the contrary, Mg2+-ATPase activity was considerably reduced with Glu concentrations lower than 4 mᴍ. The enzyme was inhibited 40%, 50% or 80% with 3, 2 or 1 mᴍ of Glu, respectively. The above results suggest: a) The various concentrations of Glu have no effect on brain Na+, K+-ATPase activity, b) The inhibited brain Mg2+-ATPase in hypoglycemia produces low intracellular Mg2+, which could modulate the activity of Mg2+ -dependent enzymes and the rates of protein syn­thesis and growth of the cell.


2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S217-S217
Author(s):  
Kentaro Deguchi ◽  
Mikiro Takaishi ◽  
Takeshi Hayashi ◽  
Atsuhiko Oohira ◽  
Shoko Nagotani ◽  
...  

2004 ◽  
Vol 10 (1) ◽  
pp. 99-104
Author(s):  
Kh.K. Muradian ◽  
◽  
A.N. Timchenko ◽  
N.A. Utko ◽  
T.A. Badova ◽  
...  

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