scholarly journals Polymorphism of Transcription Factor 7-Like 2 in Obese Patients with Type 2 Diabetes Mellitus

2020 ◽  
Vol 08 (11) ◽  
pp. 9-15
Author(s):  
Rui Xia ◽  
Defeng Kong ◽  
Xue Han ◽  
Hang Guo
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Transcription Factor ◽  
Obese Patients

AMPK AND SIRT1 IN THE REGULATION OF LIVER METABOLISM IN OBESE PATIENTS WITH TYPE 2 DIABETES MELLITUS

2021 ◽  
Author(s):  
Мария Александровна Вульф ◽  
Дарья Александровна Скуратовская ◽  
Александра Андреевна Комар ◽  
Лариса Сергеевна Литвинова
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Transcription Factor ◽  
Carbohydrate Metabolism ◽  
Liver Metabolism ◽  
Protective Role ◽  
Obese Patients

У больных ожирением выявлены взаимосвязи основных регуляторов метаболизма (AMPK и SITRT1) в печени с нарушениями со стороны липидного и углеводного обменов. Установлена протекторная роль SIRT1 в подавлении экспрессии транскрипционного фактора NF-kB в печени, способствующего переходу стеатоза в стеатогепатит. In obese patients, interrelations of the main regulators of metabolism (AMPK and SITRT1) in the liver with lipid and carbohydrate metabolism disorders were revealed. The protective role of SIRT1 in suppressing the expression of the transcription factor NF-kB in the liver, which promotes the transition of steatosis to steatohepatitis, has been established.

Real world data of Type 2 Diabetes Mellitus (T2DM) obese patients using another GLP1 receptor agonist (GLP1–RA) and switching to Semaglutide in Spain

2020 ◽  
Author(s):  
Jersy Cardenas ◽  
Gomez Nancy Sanchez ◽  
Sierra Poyatos Roberto Miguel ◽  
Luca Bogdana Luiza ◽  
Mostoles Naiara Modroño ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Real World ◽  
Receptor Agonist ◽  
Obese Patients ◽  
Real World Data ◽  
World Data

Glucagon-like peptide (GLP)-1 and leptin concentrations in obese patients with Type 2 diabetes mellitus

2000 ◽  
Vol 17 (10) ◽  
pp. 713-719 ◽  
Author(s):  
E. Mannucci ◽  
A. Ognibene ◽  
F. Cremasco ◽  
G. Bardini ◽  
A. Mencucci ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Obese Patients ◽  
Glucagon Like Peptide
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