CHAP-Hyaluronic Acid (CHAP-HA) Filler as an Optimal Candidate for Forehead Filler Augmentation Using a 3-Point Injection Technique

Among the various therapeutic options for the treatment of tear trough deformities, the use of hyaluronic acid-based fillers has constantly been increasing. The aim of this research is to conduct a systematic review of the published literature related to the use of hyaluronic acid-based dermal fillers for the treatment of tear trough deformities and possible related complications. A search of the published literature was conducted following the PRISMA guidelines, including PubMed, Cochrane Library, and Ovid databases. Text words and Medical Search Headings (MeSH terms) were used to identify nine articles included in our analysis. The most used filler was Restylane (Galderma). The injection technique was performed through the use of a cannula or, more frequently, with a needle, through the execution of boluses or retrograde release. The injection plane was predominantly the supra-periosteal layer. The most observed side effects were mild and included redness, edema, contour irregularities, bruising, and blue-gray dyschromia. The degree of patient satisfaction was high, with an optimal aesthetic result that was maintained for 6 to 12 months. Although the duration of treatment of tear trough deformities with HA fillers is not comparable to surgical treatment, this is a minimally invasive, safe procedure, quick to perform, and with a high degree of patient satisfaction.

Download Full-text

Magnetic Agarose Microspheres/Hyaluronic Acid Hydrogel as a Trackable Bulking Agent for Vesicoureteral Reflux Treatment

Frontiers in Bioengineering and Biotechnology ◽

10.3389/fbioe.2021.746609 ◽

2021 ◽

Vol 9 ◽

Author(s):

Hong Chen ◽

Pan Wu ◽

Hong Xu ◽

Changchun Wang

Keyword(s):

Hyaluronic Acid ◽

Vesicoureteral Reflux ◽

Bulking Agent ◽

Magnetic Microspheres ◽

Injection Technique ◽

Transverse Relaxation Rate ◽

Ureteral Orifice ◽

Hyaluronic Acid Hydrogel

Vesicoureteral reflux (VUR) is one of the most common congenital anomalies in the kidney and the urinary tract. Endoscopic subureteral injection of a bulking agent has become popular in VUR treatment due to its high success rates, few complications, and a straightforward procedure. In this study, a novel magnetic bulking agent was prepared by embedding Fe3O4 magnetic nanoparticles in cross-linked agarose microspheres with diameters of 80–250 μm and dispersing the magnetic microspheres in a hyaluronic acid hydrogel. The bulking agent has good biocompatibility and biosecurity validated by the tests of cytotoxicity, in vitro genotoxicity, animal irritation, skin sensitization, acute systemic toxicity, and pathological analysis after the injection of the bulking agent extract solution into healthy mice as well as injection of the bulking agent into VUR rabbits. The VUR rabbits were created by incising the roof of the intravesical ureter to enlarge the ureteral orifice. The success rate of the bulking agent in treating VUR rabbits using a subureteral transurethral injection technique was 67% (4/6) or 80% (4/5, excluding the unfinished rabbit), and no migrated particles were found in the organs of the rabbits. The transverse relaxation rate of the bulking agent was 104 mM−1s−1. After injection, the bulking agent was long-term trackable through magnetic resonance imaging that can help clinicians to inspect the VUR treatment effect. For the first time, this study demonstrates that the bulking agent with a long-term stable tracer is promising for endoscopic VUR treatment.

Download Full-text

Practical aspects and algorithms for using Cellular Matrix intradermal implant and platelet-rich plasma autologous thrombin activation technology in practice of cosmetologist

Medical alphabet ◽

10.33667/2078-5631-2019-2-26(401)-110-114 ◽

2019 ◽

Vol 2 (26) ◽

pp. 110-114

Author(s):

A. M. Pedanov ◽

A. Yu. Alenichev ◽

S. M. Fyodorov ◽

I. V. Sharypova

Keyword(s):

Hyaluronic Acid ◽

Platelet Rich Plasma ◽

Injection Technique ◽

Key Points ◽

Optimal Injection ◽

Thrombin Activation ◽

Practical Recommendations ◽

Cellular Matrix

The article describes the practical aspects of the use of modern injectable preparations rich in platelets with additional activation by autologous thrombin and in combination with hyaluronic acid (Cellular Matrix). Practical recommendations are given on the optimal injection technique, tactics for constructing courses of procedures in a mono version and in combination with hardware cosmetology procedures. The key points of interaction with patients who have indications for aesthetic correction are analyzed.

Download Full-text

Comments on heat and mass transfer characteristics of steam in a horizontal wellbore with multi-point injection technique considering wellbore stock liquid [International Journal of Heat and Mass Transfer 127 (2018) 949–958]

International Journal of Heat and Mass Transfer ◽

10.1016/j.ijheatmasstransfer.2018.12.083 ◽

2019 ◽

Vol 132 ◽

pp. 1319-1321 ◽

Cited By ~ 4

Author(s):

Fengrui Sun ◽

Yuedong Yao ◽

Guozhen Li

Keyword(s):

Mass Transfer ◽

Heat And Mass Transfer ◽

Injection Technique ◽

Transfer Characteristics ◽

Point Injection ◽

Horizontal Wellbore

Download Full-text

Application of Supercritical Water Coupled with Toe-Point Injection Technique for Heavy Oil EOR: A Case Study

10.2118/193720-ms ◽

2018 ◽

Author(s):

Shiyuan Qu ◽

Hanqiao Jiang ◽

Junjian Li ◽

Jinchuan Hu ◽

Fengrui Sun ◽

...

Keyword(s):

Supercritical Water ◽

Heavy Oil ◽

Injection Technique ◽

Point Injection

Download Full-text

MD Codes™: A Methodological Approach to Facial Aesthetic Treatment with Injectable Hyaluronic Acid Fillers

Aesthetic Plastic Surgery ◽

10.1007/s00266-020-01762-7 ◽

2020 ◽

Cited By ~ 1

Author(s):

Maurício de Maio

Keyword(s):

Patient Satisfaction ◽

Hyaluronic Acid ◽

Methodological Approach ◽

Full Description ◽

Injection Technique ◽

Symbolic Language ◽

Level Of Evidence ◽

Delivery Technique ◽

The Face ◽

Facial Attributes

Abstract Background Patients often seek aesthetic correction of facial deficiencies (e.g., lines and folds) that are rarely the underlying cause of dissatisfaction with their appearance. Use of a more holistic approach focused on improving the emotional messages of the face (e.g., looking less sad) may improve patient satisfaction with treatment outcomes. The MD Codes™ system was developed to increase clinician success rates by reducing variability in the technical aspects of hyaluronic acid (HA) filler treatment and focusing on addressing unfavorable emotional attributes of the face. Methods The MD Codes, or medical codes, represent specific anatomical subunits for injection of HA fillers. Each MD Code includes information regarding the target depth of injection, the proper delivery tool (needle or cannula) and delivery technique (e.g., aliquot, bolus, fanning), and the minimum product volume recommended to achieve visible, reproducible results (active number). During treatment planning, the appropriate MD Codes are selected using algorithms focused on lessening unfavorable facial attributes (a saggy, tired, sad, or angry look) and enhancing positive attributes (an attractive, younger, more contoured, or feminine [soft] or masculine look). Results Three case studies are presented to illustrate how the MD Codes and their algorithms were used to address sagginess, tiredness, and sadness in two women and one man. Conclusions MD Codes provide a universal symbolic language for reducing variability in injection technique. The platform provides user-friendly algorithms to help clinicians increase patient satisfaction by going beyond treatment of lines and folds and to focus on reducing unfavorable facial attributes. Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Download Full-text