A web-based interface to calculate phonological neighborhood density for words and nonwords in Modern Standard Arabic

The availability of online databases (e.g., Balota et al., 2007) and calculators (e.g., Storkel & Hoover, 2010) has contributed to an increase in psycholinguistic-related research, to the development of evidence-based treatments in clinical settings, and to scientifically supported training programs in the language classroom. The benefit of online language resources is limited by the fact that the majority of such resources provide information only for the English language (Vitevitch, Chan & Goldstein, 2014). To address the lack of diversity in these resources for languages that differ phonologically and morphologically from English, the present article describes an online database to compute phonological neighborhood density (i.e., the number of words that sound similar to a given word) for words and nonwords in Modern Standard Arabic (MSA). A full description of how the calculator can be used is provided. It can be freely accessed at https://calculator.ku.edu/density/about.

The Environmental Pollutant Bromophenols Interfere With Sulfotransferase That Mediates Endocrine Hormones

Bromophenols (BPs), known as an important environmental contaminant, can cause endocrine disruption and other chronic toxicity. The study aimed to investigate the potential inhibitory capability of BPs on four human sulfotransferase isoforms (SULT1A1, SULT1A3, SULT1B1 and SULT1E1) and interpret how to interfere with endocrine hormone metabolism. P-nitrophenol(PNP) was utilized as a nonselective probe substrate, and recombinant SULT isoforms were utilized as the enzyme resources. PNP and its metabolite PNP-sulfate were analyzed using a UPLC-UV detecting system. SULT1A1 and SULT1B1 were demonstrated to be the most vulnerable SULT isoforms towards BPs’ inhibition. To determine the inhibition kinetics, 2,4,6-TBP and SULT1A3 were selected as the representative BPs and SULT isoform respectively. The competitive inhibition of 2,4,6-TBP on SULT1A3. The fitting equation was y=90.065x+1466.7, and the inhibition kinetic parameter (Ki) was 16.28 µM. In vitro-in vivo extrapolation (IVIVE) showed that the threshold concentration of 2,4,6-TBP to induce inhibition of SULT1A3 was 1.628 µM. In silico docking, the method utilized indicated that more hydrogen bonds formation contributed to the stronger inhibition of 3,5-DBP than 3-BP. In conclusion, our study gave the full description of the inhibition of BPs towards four SULT isoforms, which may provide a new perspective on the toxicity mechanism of BPs and further explain the interference of BPs on endocrine hormone metabolism.

Daily Variation in Sampled Densities of Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) Nymphs at a Single Site—Implications for Assessing Acarological Risk

The public health challenge posed by tick-borne disease (TBD) has increased efforts to characterize the spatial and temporal distribution of ticks and associated pathogens to better focus tick control strategies and personal protection measures. We describe variability in nymphal Ixodes scapularis Say and Amblyomma americanum (L.) density derived from daily drag sampling at a single location in New Jersey over 4 yr and explore how observed differences in daily collections might affect the estimation of acarological risk. We found significant variability in the density of host-seeking nymphs that could suggest substantially different rates of human-tick encounters depending on sampling date, habitat, and ambient weather conditions. The spatial and temporal variability in the distribution of 2 sympatric tick species with different host preferences and questing strategies, suggests that to produce results that are comparable among sites across the area sampled, surveillance efforts may be limited to shorter collection seasons, fewer sites or less sampling effort (fewer plots or fewer visits) per site, and a geographic scope that minimizes the potential temporal and spatial biases indicated here. Our results illustrate that evaluation of models of tick distribution or relative acarological risk based on surveillance data requires a full description of the diversity of habitats sampled and the conditions under which sampling is performed. The array of factors that affect tick host-seeking and that could bias interpretation of sampling results emphasizes the need to standardize sampling protocols and for more caution when interpreting tick sampling data collected over large temporal and spatial scales.

The fruit fly fauna (Diptera: Tephritideae: Dacinae) of Papua New Guinea, Indonesian Papua, Associated Islands and Bougainville

The species within the Tribe Dacini from Papua New Guinea, Indonesian Papua (West Papua, Central Papua, Papua), associated islands and Bougainville are recorded. In all, 296 species are recorded including 65 new species described herein. The new species are treated under two genera, Bactrocera Macquart (eight subgenera) and Dacus Fabricius (three subgenera). The following new species are described and illustrated: Bactrocera (Bactrocera) atriscuta, B. (B.) bisianumu, B. (B.) bogiae, B. (B.) bubiae, B. (B.) bukaensis, B. (B.) caccabata, B. (B.) centraliae, B (B.) dysoxyli, B. (B.) expandosa, B. (B.) fumica, B. (B.) gabensiae, B. (B.) kaiauiae, B. (B.) kauiae, B. (B.) keravatiae, B. (B.) kokodiae, B. (B.) kunvawaensis, B. (B.) labubulu, B. (B.) laensis, B. (B.) manusiae, B. (B.) meraiensis, B. (B.) monostriata, B. (B.) neoabdonigella, B. (B.) neoaeroginosa, B. (B.) ohuiae, B. (B.) paraendiandrae, B. (B.) paraochracea, B. (B.) pometiae, B. (B.) raunsepnaensis, B. (B.) rounaensis, B (B.) rutilana, B. (B.) saramandiae, B. (B.) sari, B. (B.) sylvania, B. (B.) tikelingiae, B. (B.) trivirgulata, B. (B.) waidoriae, B. (B.) yayamiae, Bactrocera (Bulladacus) curiosa, Bactrocera (Calodacus) insolita, Bactrocera (Hemizeugodacus) neoaglaiae, B. (H.) wilhelmiae, Bactrocera (Neozeugodacus) leblanci, Bactrocera (Semicallantra) cerberae, B. (S.) malasaitiae, Bactrocera (Tetradacus) arbuscula, B. (T.) novotnyi, B. (T.) procera, Bactrocera (Zeugodacus) aiyurae, B. (Z.) anglimpiae, B. (Z.) bainingsiae, B. (Z.) madangiae, B. (Z.) magiae, B. (Z.) mitparingii, B. (Z.) oiyaripensis, B. (Z.) parasepikae, B. (Z.) rufoscutella, B. (Z.) xanthovelata, Dacus (Callantra) nigrolobus, D. (Mellesis) alatifuscatus, Dacus (Neodacus) asteriscus, D. (N.) bimaculosus, D. (N.) curvabilis, D. (N.) kreeriae, D. (N.) lalokiae and D. (N.) neosignatifrons. Females of B. (Bactrocera) daruensis Drew, B. (Bactrocera) nigella (Drew) and B. (Bactrocera) thistletoni Drew are described and a revised description of B. (Bactrocera) torresiae Huxham & Hancock is presented. Bactrocera (Bactrocera) denigrata (Drew) is withdrawn from synonymy with B. longicornis Macquart, and a full description of B. longicornis is presented from a study of the holotype and 27 newly collected specimens. New geographical distribution, host plant and male lure records are presented for some species. The major pest species that occur in the geographical region covered by this publication are reviewed and their biosecurity risks to other regional countries discussed. The land mass of Papua New Guinea and Indonesian Papua contains a richer fauna than any other from South-east Asia to the eastern Pacific, presumably resulting from speciation in the rich rainforest ecosystem. Differences of opinion on the status of some species in the Bactrocera dorsalis complex and on the supraspecific classification within the genus Bactrocera are evident in the literature. We have acknowledged and discussed these differences and, as authors, have presented conclusions based on our own research data.

MEDIEVAL COINS ON THE TERRITORY OF UKRAINE. “BRUSH STROKES” TO THE MONETARY CIRCULATION (I)

During the past two decades, with the development of private search using a special equipment, the number of known coins has increased dramatically, opening up the new opportunities for researchers. The aim of the study. Some of these finds, mainly treasures, have been the subject of the specialized research or have been the part of various numismatic publications, which cannot be said of isolated finds that have only been partially covered in the scientific literature. At the same time, the individual finds are not inferior to informative treasures, allowing a reconstructing the monetary circulation of a single settlement or city, its economic potential, interregional trade relations and many other aspects that contribute together to the restoration of the historical past. Over the last 10-15 years, the authors of this article have been systematically collecting information about the medieval coins found in Ukraine, some of which have an exact location. Thus, the purpose of this article is the gradual introduction into scientific circulation of the numismatic material originating from the territory of modern Ukraine with its full description, illustrations and outlines, references to current works and catalogues. It opens a series of articles on issues of the XV and XVII centuries, namely the Moldavian coins of Alexander I the Good, Stephen III the Great and one piece of the crown solidus of Sigismund III, found with them. Within the 22 coins described in the article, about 10 were found: 6 coins originate from Chernivtsi region, 1 piece of Moldovan coins were founded in Vinnytsia, Poltava, Volyn and Lviv regions. Other coins were also found on the territory of modern Ukraine, the authors do not know the exact places of their discovery. The Conclusions. The topographic distribution of the finds indicates that the main zone of concentration of Moldavian coins falls on the Chernivtsi region, which is quite natural, given that these lands, mentioned in written sources under the name of Shipinska land (terra Sepenicensis), were was included the part of the Moldavian principality since the end of XIV century. The distribution of Moldovan coin finds in Ukraine corresponds to the same international trade routes that connected Central Europe with the Crimean Peninsula, passing through the territory of modern Ukraine and Moldova, known as «Tatar» and «Moldovan» trade routes; and the mediating the role played by the lands of the Principality of Moldavia in this trade.

Ancient parks and gardens of Northern and Eastern India

The 30 ancient gardens of Northern India were studied: 9 palace gardens, 13 memorial gardens (at tombs), 8 gardens of “royal rest”, and 2 ancient botanical gardens of West Bengal (East India) for 11 years (from 2008 to 2019). Brief information is given for each object: the year of the garden' s foundation, the size, historical objects on the territory of the park (garden), the presence of old-age trees and some tree species is noted; inaccessible and / or rarely visited ancient gardens are described in more detail (Mughal Gardens in Delhi, Yadavindra Gardens in Pinjor and others). A full description of the ancient gardens (parks) of India is given in the publications of the authors, a list of which is given.

Optical Flow Tracking Velocimetry of Near-Field Explosions

To better understand the complex dynamics and physics associated with the rapid expansion of the detonation product fireball following an explosion, it is imperative to have a full description of its associated velocity field. Typical experimental techniques rely on simple single-point measurements captured from pressure transducers or Hopkinson pressure bars. In this technical design note, we aim to improve the current state-of-the-art by introducing a means to determine full velocity fields from high-speed video using Optical Flow Tracking Velocimetry. We demonstrate the significance of this method from our results by comparing velocity fields derived from high-speed video and a validated numerical model of the same case. A wider use of this technique will allow researchers to elucidate spatial and temporal features of explosive detonations, which could not be obtained thus far using single- point measurements.

Complications and Disasters After Minimally Invasive Tissue Augmentation with Different Types of Fillers: A Retrospective Analysis

Background The interest in youthful appearance and rejuvenating procedures is unbroken in our society. Besides surgical procedures, permanent fillers are utilized. The incorrect and unprofessional use of these substances, auto-injections in particular, have devastating results for patients and are challenging for the plastic surgeon. The aim of this retrospective study was to delineate the differences between permanent and non-permanent filler complications and appropriate treatment options. Methods We conducted a retrospective study and researched the hospital information system in the time period from 2001 to 2020. Patients with unprofessional use of permanent fillers, auto-injections and injections of unformulated substances were determined. Age, gender, localization, complications, length of hospital stay, comorbidities, histopathological workups and surgical salvage procedures were noted. Descriptive statistics were calculated. Results Seventeen patients were identified from 2001 till 2020. In four cases, auto-injections by the patients were the cause, whereas in the other patients the injections were performed by medical staff. Ages range from 18 to 57 years. Fourteen patients were female and three were male. The injected substances could be recognized as synthol, silicone, vaseline, fat tissue, hyaluronic acid as well as non-medical substances. Surgical procedures were necessary in eleven cases. One patient died because of the underlying diseases. Conclusion Our results indicate different sequels of filler materials injected in an unprofessional way, possible complications, conservative and surgical techniques to resolve these rare complications. We suggest a staged therapy adjusted to the clinical symptoms. Milder symptoms can be handled conservatively, whereas severe infections, skin breakdowns or persistent granuloma are justifying indications for surgical treatment. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Dynamics of Event Processes in the Information Society: Social Functions of Fake and Hype

Introduction. The article examines the phenomenon of fake, the factors of its occurrence, development and destruction. Despite the fact that the concept of fake has become popular and has acquired a large number of definitions, the discussion around the definition of this concept continues to the present. Fake and hype, each separately, becomes the subject of research and there is already a detailed classification of them. Fake, like hype, is usually understood as negative, misleading and distracting phenomena. Meanwhile, they represent a phenomenon of stable interaction. A fake can trigger a hype wave and a subsequent series of events. At the same time, the tangible discomfort of this phenomenon is especially emphasized. The relevance of the study is due to the need to consider these phenomena as positive processes, to show their role and functions from a new, positive point of view. The purpose of the article is to describe the hidden social functions of the phenomenon of fake and hype, their mutual inclusion, their positive role in the processes of the formation of social reality.Methodology and sources. The source of the research was the discussion on fakes and presented in the collective monograph “Fakes: Communication, Meanings, Responsibility” edited by G.L. Tulchinsky. In the article, to create dynamic models of events, the theory of latent oscillations and stability of control systems were used, N.V. Kuznetsova and the classical theory of oscillatory and wave processes in the interpretation of N.V. Karlov, N.A. Kirichenko.Results and discussion. As a result of the study, an important connection between fake and hype was traced. A fake triggers a reaction in the form of a hype, which in turn gives competitive advantages to all participants in the process: persons, social and subcultural groups, institutions, states and their unions. In addition to the negative impact of a fake on a person and social reality, there are many cases when a fake is a necessary phenomenon in social and cultural processes. In the conditions of traditionally high competition in the processes of achieving each subsequent step of the social and career ladder, fake is one of the necessary elements for achieving competitive superiority. Hype, like fake, can act not only as an annoying and negative factor, but also as a necessary element in the balanced development of society and public communication space. Using a fake as a triggering event to generate a hype wave can be used to construct social reality. Modeling the dynamics of event processes allows you to create a communication environment with pre-built properties, use special events as an effective tool for managing socio-cultural processes.Conclusion. Fake and the hype generated by it are a necessary element of the evolutionary development of social reality and culture, therefore, consideration of the positive consequences of these phenomena is so necessary for a full description of the socio-cultural processes generated by them, a balanced study of the processes of the formation of social reality.

Reliability and Effectiveness of Sprinkler Systems in Poland

The article presents research on the reliability and effectiveness of sprinkler systems in selected countries around the world as well as results of similar studies conducted in Poland based on the data of the State Fire Service. First discussed are the specifics of analysed data and the problems regarding its acquisition and presentation in a simplified form without proper reflection and the assessment of its specificity, quality, detail, uncertainty and completeness. The next step presents the methodology of detailed data analysis based on full description of fire events and the segregation of fire events into separate subcategories. Such an analysis allowed the presumption that in the five-year period 2013–2017, in 94.4% of relevant fire events sprinkler systems in Poland have demonstrated the achievement of their intended goals. This result is similar to the results achieved in other countries known for high level of fire safety culture (USA, UK, Sweden). In the author’s opinion, this proves the high immanent reliability of these systems, which results from their simple construction and proper maintenance, and not from the country in which they were installed. Taking into account these results, it is recommended that Poland should update its regulations in a manner similar to that of developed countries, so that they take into account in a greater extent the protective value and characteristics of sprinkler systems and the benefits resulting from their application. It is also recommended to increase the detail of publicly collected data on fire protection systems in buildings because better knowledge about the characteristics of these systems in Poland may allow achieving an even higher level of their reliability and effectiveness.