scholarly journals The use of autologous platelet-rich plasma in the treatment of intractable skin ulcer: A case series

2012 ◽  
Vol 01 (03) ◽  
pp. 29-32 ◽  
Author(s):  
Natsuko Kakudo ◽  
Satoshi Kushida ◽  
Tsunetaka Ogura ◽  
Tomoya Hara ◽  
Kenji Suzuki ◽  
...  
2019 ◽  
Vol 11 (2) ◽  
pp. 50-52
Author(s):  
Sanjeewani Fonseka ◽  
Y.M.D.M Bandara ◽  
Brabaharan Subhani

Abstract Introduction. Alopecia areata (AA) is an autoimmune disease-causing non-scarring alopecia. It is usually treated with immunosuppressive agents, to which some patients fail to respond adequately. Material and Methods. Three patients with AA refractory to standard therapy were treated with intra-dermal injection of autologous platelet rich plasma (PRP) every four weeks. Results. All three patients showed remarkable improvement after multiple sessions of PRP treatment. Conclusion. Autologous PRP is safe and effective in treatment-resistant forms of AA demonstrated in many case reports; therefore it deserves further study with randomized, placebo-controlled trials.


2011 ◽  
Vol 69 (9) ◽  
pp. 2465-2472 ◽  
Author(s):  
Marcos Martins Curi ◽  
Giuliano Saraceni Issa Cossolin ◽  
Daniel Henrique Koga ◽  
Cristina Zardetto ◽  
Silmara Christianini ◽  
...  

2011 ◽  
Vol 0 (1) ◽  
pp. 66
Author(s):  
S M Noskov ◽  
Larisa Yur'evna Shirokova ◽  
A V Arshinov ◽  
S D Dybin ◽  
S M Mayorova ◽  
...  

2017 ◽  
Vol 5 (1) ◽  
pp. 15 ◽  
Author(s):  
Mohamed M. Raslan ◽  
Nader M. Milad ◽  
Ahmed Abd AlAziz

Background: Chronic ulcers are a big health problem worldwide. Having a great impact at personal, social and professional levels. The use of autologous Platelet Rich Plasma (PRP) is a major advance in the treatment of these ulcers as an easy and cost-effective method. Platelets provide numerous growth factors enhancing tissue healing. The aim of this study was to evaluate the safety and efficacy of autologous platelet-rich plasma as a treatment of chronic non-healing ulcers.Methods: Autologous PRP was prepared from whole blood by centrifugation and activated by 10% calcium chloride. Twenty-Four (24) patients with non-healing ulcers of different etiologies, whom they met our inclusion criteria, were treated with PRP injected every two weeks locally into their wounds until healing. The ulcer dimensions were measured every week. The follow-up period was 12 weeks after healing.Results: The mean age of the study population 41±21 years. Complete healing was achieved in all patients. The mean rate of healing (average decrease in ulcer dimensions) was 0.48 cm/week. The rate of healing was greater at the week following injection. The mean time for healing was 6.11 weeks.Conclusions: Author witnessed the useful effects of PRP application on enhancing wound healing. The results from our case series showed that PRP is a safe and effective treatment for the promotion of healing chronic ulcers. Further research and controlled, randomized prospective clinical trials on larger patient population are important to validate our results.


2015 ◽  
Vol 42 (3) ◽  
pp. 288-295 ◽  
Author(s):  
Rie R. Yotsu ◽  
Shotaro Hagiwara ◽  
Hitoshi Okochi ◽  
Takeshi Tamaki

F1000Research ◽  
2012 ◽  
Vol 1 ◽  
pp. 68 ◽  
Author(s):  
Robert Vander Kraats ◽  
Arockia Doss

Background: Labral tears commonly occur in both the general and sporting population, often leading to significant pain and dysfunction. Patients often engage in progressive rehabilitative programs, and surgical intervention may be required in severe cases. Autologous platelet rich plasma (PRP) injections have been growing in popularity in musculoskeletal medicine as an alternative to corticosteroid injections. This paper looks at the effectiveness of PRP injections in glenoid labral lesions.Methods: The clinical and radiological findings are presented for two patients who have been treated with autologous PRP into the glenohumeral joint adjacent to the labral tear, in conjunction with a progressive rehabilitative program. Follow up occurred at 18 months and 13 months, respectively.Results: Both subjects tolerated the PRP injection well with no adverse effects, and were compliant with their rehabilitative programs. On initial presentation, pain on the visual analogue scale (VAS) was 7/10 and 6/10 and at follow up it was reported as 0/10. Both subjects have now returned to normal sporting and work activities.Conclusions: The findings from this case series suggest that PRP in conjunction with appropriate rehabilitation can assist in the clinical recovery of glenoid labral tears. Further research is required with greater sample numbers and improved methodological parameters.


2018 ◽  
Vol 20 ◽  
pp. 54-57
Author(s):  
Krishnaiah Kurapati ◽  
Praveen Kumar G.V. ◽  
Kavitha Anbarasu ◽  
Anand Kumar Vaggu ◽  
Vibhuda Nanduri ◽  
...  

Esculapio ◽  
2021 ◽  
Vol 16 (4 (oct 2020 - dec 2020)) ◽  
Author(s):  
Nadia Naeem ◽  
Saadiya Siddiqui ◽  
Atif Shehzad ◽  
Kehkshan Tahir ◽  
Marrium Manzoor

Objective: To assess the outcome of autologous platelet rich plasma(PRP) for the treatment of androgenetic alopecia in male patients. Methods: A total of 61 male patients from Department of Dermatology, Lahore General Hospital Lahore with ages between 18-60 years were included in the study during a period of 6 months. PRP was prepared by double spin method and CaCl2 was used to activate platelets. PRP was injected, with a 30-G needle using Nappage technique. This descriptive case series study was carefully monitored. Protocol included three treatment sessions with an interval of four weeks. Number of hairs, and hair strength was assessed by dermoscopy and hair pull test. SPSS Version-21 was used for data entry and analysis. Results: The mean age of patients was 42.67±8.63 years. Mean number of hair was 21.50±4.57 per dermatoscopic field, Post treatment number of hair was 78.10±16.24. Mean duration of disease was 10.25±3.52 months. Majority of patients were in stage iv 19(31.1%) and in stage ii 16(26.2%). There was significant difference in number of hair before and after treatment. Conclusion: PRP is an effective method to treat the patients with androgen alopecia. Key Words: Autologus platelet rich plasma, Androgen alopecia. How to Cite: Naeem N, Siddiqui S, Shehzad A, Tahir K, Manzoor M. Efficacy of autologous platelet rich plasma in the treatment of male androgenetic alopecia. Esculapio.2020;16(04):41-45.


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