scholarly journals Modulation of Interval–Force Dependence of Rat Papillary Muscle at Acute and Course Exposure of Amiodarone

2012 ◽  
Vol 03 (03) ◽  
pp. 342-347 ◽  
Author(s):  
Sergey Afanasiev ◽  
Dina Kondratyeva ◽  
Sergey Popov ◽  
Roman Batalov
Keyword(s):  
Papillary Muscle ◽  
Rat Papillary Muscle

Mechanical restitution of the rat papillary muscle

1982 ◽  
Vol 115 (2) ◽  
pp. 183-191 ◽  
Author(s):  
KRISTÍN RAGNARSDÓTTIR ◽  
BJÖRN WOHLFART ◽  
MAGNÚS JÓHANNSSON
Keyword(s):  
Papillary Muscle ◽  
Mechanical Restitution ◽  
Rat Papillary Muscle

Adriamycin-induced alterations of the action potential in rat papillary muscle

1980 ◽  
Vol 14 (8) ◽  
pp. 446-450 ◽  
Author(s):  
M L LAZARUS ◽  
K L ROSSNER ◽  
K M ANDERSON
Keyword(s):  
Action Potential ◽  
Papillary Muscle ◽  
Rat Papillary Muscle

Acute and specific collagen type I degradation increases diastolic and developed tension in perfused rat papillary muscle

2004 ◽  
Vol 286 (3) ◽  
pp. H889-H894 ◽  
Author(s):  
Regis R. Lamberts ◽  
Maurice J. J. M. F. Willemsen ◽  
Néstor G. Pérez ◽  
Pieter Sipkema ◽  
Nico Westerhof
Keyword(s):  
Papillary Muscle ◽  
Collagen Type ◽  
Perfusion Pressure ◽  
Collagen Type I ◽  
Type I ◽  
Collagenase Treatment ◽  
Before And After ◽  
Diastolic Coronary Flow ◽  
Rat Papillary Muscle

Collagen degradation is suggested to be responsible for long-term contractile dysfunction in different cardiomyopathies, but the effects of acute and specific collagen type I removal (main type in the heart muscle) on tension have not been studied. We determined the diastolic and developed tension length relations in isometric contracting perfused rat papillary muscles (perfusion pressure 60 cmH2O) before and after acute and specific removal of small collagen struts with the use of purified collagenase type I. At 95% of the maximal length (95% Lmax), diastolic tension increased 20.4 ± 8.1% ( P < 0.05, n = 6) and developed tension increased 15.0 ± 6.7% after collagenase treatment compared with time controls. Treatment increased the diastolic muscle diameter by 7.1 ± 3.4% at 95% Lmax, whereas the change in diameter due to contraction was not changed. Diastolic coronary flow and normalized coronary arterial flow impediment did not change after collagenase treatment. Electron microscopy revealed that the number of small collagen struts, interconnecting myocytes, and capillaries was reduced to ∼32% after treatment. We conclude that removal of the small collagen struts by acute and specific collagen type I degradation increases diastolic and developed tension in perfused papillary muscle. We suggest that diastolic tension is increased due to edema, whereas developed tension is increased because the removal of the struts poses a lower lateral load on the cardiac myocytes, allowing more myocyte thickening.

Determination of efficiency of isolated hypertrophic and control rat papillary muscle from work and oxygen used

2008 ◽  
Vol 44 (4) ◽  
pp. 755
Author(s):  
Y.Y. Wong ◽  
M.L. Handoko ◽  
F.S. de Man ◽  
K.T.B. Mouchaers ◽  
A. Vonk-Noordegraaf ◽  
...  
Keyword(s):  
Papillary Muscle ◽  
And Control ◽  
Rat Papillary Muscle

Enhanced ?-adrenergic response in rat papillary muscle by inhibition of inducible nitric oxide synthase after myocardial infarction

2007 ◽  
Vol 190 (2) ◽  
pp. 111-117 ◽  
Author(s):  
V. D. Pinto ◽  
G. J. S. Cutini ◽  
C. L. Sartório ◽  
A. S. Paigel ◽  
D. V. Vassallo ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Myocardial Infarction ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Papillary Muscle ◽  
Adrenergic Response ◽  
Oxide Synthase ◽  
Rat Papillary Muscle ◽  
Inducible Nitric Oxide

Effect of Nifedipine on Rat Papillary Muscle and Perfused Heart

1984 ◽  
pp. 179-185
Author(s):  
P. Braveny ◽  
J. S. Juggi ◽  
G. Telahoun
Keyword(s):  
Papillary Muscle ◽  
Perfused Heart ◽  
Rat Papillary Muscle

Age-related differences in excitation-contraction coupling in rat papillary muscle

1983 ◽  
Vol 78 (5) ◽  
pp. 492-504 ◽  
Author(s):  
J. M. Capasso ◽  
R. M. Remily ◽  
E. H. Sonnenblick
Keyword(s):  
Papillary Muscle ◽  
Excitation Contraction Coupling ◽  
Contraction Coupling ◽  
Age Related ◽  
Rat Papillary Muscle
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