scholarly journals Association of genetic variations in the ACLY gene with growth traits in Chinese beef cattle

2016 ◽  
Vol 15 (2) ◽  
Author(s):  
M.N. Li ◽  
X. Guo ◽  
P.J. Bao ◽  
X.Y. Wu ◽  
X.Z. Ding ◽  
...  
2021 ◽  
Vol 53 (1) ◽  
Author(s):  
Emmanuel A. Lozada-Soto ◽  
Christian Maltecca ◽  
Duc Lu ◽  
Stephen Miller ◽  
John B. Cole ◽  
...  

Abstract Background While the adoption of genomic evaluations in livestock has increased genetic gain rates, its effects on genetic diversity and accumulation of inbreeding have raised concerns in cattle populations. Increased inbreeding may affect fitness and decrease the mean performance for economically important traits, such as fertility and growth in beef cattle, with the age of inbreeding having a possible effect on the magnitude of inbreeding depression. The purpose of this study was to determine changes in genetic diversity as a result of the implementation of genomic selection in Angus cattle and quantify potential inbreeding depression effects of total pedigree and genomic inbreeding, and also to investigate the impact of recent and ancient inbreeding. Results We found that the yearly rate of inbreeding accumulation remained similar in sires and decreased significantly in dams since the implementation of genomic selection. Other measures such as effective population size and the effective number of chromosome segments show little evidence of a detrimental effect of using genomic selection strategies on the genetic diversity of beef cattle. We also quantified pedigree and genomic inbreeding depression for fertility and growth. While inbreeding did not affect fertility, an increase in pedigree or genomic inbreeding was associated with decreased birth weight, weaning weight, and post-weaning gain in both sexes. We also measured the impact of the age of inbreeding and found that recent inbreeding had a larger depressive effect on growth than ancient inbreeding. Conclusions In this study, we sought to quantify and understand the possible consequences of genomic selection on the genetic diversity of American Angus cattle. In both sires and dams, we found that, generally, genomic selection resulted in decreased rates of pedigree and genomic inbreeding accumulation and increased or sustained effective population sizes and number of independently segregating chromosome segments. We also found significant depressive effects of inbreeding accumulation on economically important growth traits, particularly with genomic and recent inbreeding.


1993 ◽  
Vol 34 (1-2) ◽  
pp. 57-70 ◽  
Author(s):  
D.F. Waldron ◽  
C.A. Morris ◽  
R.L. Baker ◽  
D.L. Johnson

2021 ◽  
Vol 30 (2) ◽  
pp. 149-156
Author(s):  
O. O Mgbere ◽  
O. Olutogun

Genetic parameters for Absolute Growth Rate (AGR), Relative Growth Rate (RGR) and Absolute Maturing Rate (AMR) at various age interval from birth to maturity in N 'Dama beef cattle raised in the humid Tropics of Nigeria were estimated. Performance data used were accumulated between 1948 and 1964 at Fasola cattle ranch in Oyo, Nigeria and the number of records analysed ranged from 44 to 678. prewering (B - W) growth and maturing rates in N’Dama calves were 0.377 ± 0.009 kg/day (AGR), 0.643 ± 0.006 %/day (RGR) and 0.120 ± 0.003% A/day (AMR) and fluctuated subsequently, following the animals' state of development and certain physiological stress conditions.  At post weaning (W-12), these rates decreased to 0.249 ± 0.049 kg/day, 0.204 ± 0.029 %/day and 0.075 ± 0.014 % A/day for AGR, RGR and AMR respectively. Estimates of heritability at the various age intervals were considered low in these growth traits with values obtained ranging from 0.03 to 0.24 for AGR, 0.03 to 0.21 for RGR and 0.02 to 0.42 for AMR, with high standard errors. The low estimates though, consistent with literature reports were attributed to the poor standard of animal management and production environment at Fasola. It was evident from this study that selection of N'Dama calves based on post weaning (W-12) growth or maturing rates would yield substantial genetic progress. However, improved animal management and production environment on the ranch would not only improve precision of the genetic parameter estimates but would also enhance N 'Dama growth performance generally.


PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e94802 ◽  
Author(s):  
Marcos E. Buzanskas ◽  
Daniela A. Grossi ◽  
Ricardo V. Ventura ◽  
Flávio S. Schenkel ◽  
Mehdi Sargolzaei ◽  
...  

2011 ◽  
Vol 50 (No. 1) ◽  
pp. 14-21 ◽  
Author(s):  
E. Krupa ◽  
M. Oravcová ◽  
P. Polák ◽  
J. Huba ◽  
Z. Krupová

Growth traits of purebred calves of six beef breeds (Aberdeen Angus – AA, Blonde d’Aquitaine – BA, Charolais – CH,Hereford – HE, Limousine – LI and Beef Simmental – BS) born from 1998 to 2002 were analysed. Traits under study were birth weight (BW), weight at 120 days (W120), weight at 210 days – weaning weight (WW), weight at 365 days – yearling weight (YW) and average daily gains from birth to 120 days (ADG1), from birth to 210 days (ADG2), from birth to 365 days (ADG3), from 120 to 210 days (ADG4). General linear model with class effects of breed, dam’s age at calving, sex, herd-year-season (HYS) and covariation of age at weighing was used for analyses. All effects significantly affected both weight and gain traits except for dam’s age that was significant for BW, W120, YW and ADG3, and age at weighing that was significant for W120, WW, YW, ADG2, ADG3, ADG4. Estimated least squares means of growth traits were compared using Scheffe’s multiple-range tests. Highest BW (40.57 kg) and W120 (172.43 kg) were found for BA calves. BS calves had highest WW (260.30 kg), YW (424.07 kg), ADG1 (1 154 g), ADG2 (1 053 g), ADG3 (1 054 g) and ADG4 (1 098 g). Highest BW, YW, ADG3 and ADG4 were found for males-singles. Males-twins had highest W120, WW, ADG1 and ADG2. Calves descending from 5–7 years old dams had highest BW, W120, WW, ADG1, ADG2 and ADG4. The proportion of variability of growth traits explained by HYS effect (42.96–71.69%) was high, whereas proportions of variability explained by SEX effect (2.03–5.77%), age of dam (1.02–2.24%) and breed (1.05–2.21%) were low. Residuals accounted for 23.71 up to 53.79% of total variance.  


2020 ◽  
Vol 98 (10) ◽  
Author(s):  
Lisa G Hohmann ◽  
Christina Weimann ◽  
Carsten Scheper ◽  
Georg Erhardt ◽  
Sven König

Abstract The objectives of this study were to investigate milk casein polymorphisms in dams and to determine the impacts of maternal casein genotypes on growth traits of their sucking calves. Milk samples from 433 dams of the breeds German Angus (GA) and German Simmental (GS) were typed at the milk protein loci α s1-casein (αs1-CN), β-casein (β-CN), α s2-casein (αs2-CN), and κ-casein (κ-CN) via isoelectric focusing. Associations between casein genotypes in maternal milk with growth traits of their 1,872 calves were analyzed until the age of weaning using linear mixed models, considering either genotypes of individual casein loci (model 1) or composite α s1-β-α s2-κ-CN genotypes within the casein cluster (model 2). Besides environmental effects such as sex, age of the dam, and calving year-season, genetic effects (breed group and maternal and paternal effects) were considered in statistical models. The composite casein genotype BBǀA2A2ǀAAǀAB (order of genes on bovine chromosome 6: α s1-ǀβ-ǀα s2-ǀκ-CN) was associated with greater average daily weight gains (ADG) and heavier age-adjusted weaning weights (WW) of calves (P < 0.05). The effects of composite genotypes on birth weight of calves were similar (P > 0.05; model 2). With regard to individual casein loci, greater ADG and WW were observed for calves from dams with the genotypes κ-CN BB and α s1-CN BB, respectively (P < 0.05; model 1). Age-adjusted WW was largest for calves from dams carrying the κ-CN genotype BB (215 kg) compared with calves representing the maternal AB and AA genotypes (both 204 kg). Results from the present study suggested selectable casein genotypes due to their nutritional value of milk (value in terms of offspring performances), offering new perspectives for breeding strategies in beef cattle to improve preweaning calf performance.


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