scholarly journals The 13C-Glucose Breath Test for Insulin Resistance Assessment in Adolescents: Comparison with Fasting and Post-Glucose Stimulus Surrogate Markers of Insulin Resistance

2016 ◽  
Vol 8 (4) ◽  
pp. 419-424 ◽  
Author(s):  
Jorge Maldonado-Hernández ◽  
Azucena Martínez-Basila ◽  
Alejandra Salas-Fernández ◽  
José R. Navarro-Betancourt ◽  
Mónica I. Piña-Aguero ◽  
...  
2009 ◽  
Vol 7 (3) ◽  
pp. 215-220 ◽  
Author(s):  
Dipanjan Banerjee ◽  
Naval Vikram ◽  
Puneet Mishra ◽  
Rajesh Bhatt ◽  
Surya Prakash ◽  
...  

2019 ◽  
Vol 56 (8) ◽  
pp. 923-929 ◽  
Author(s):  
Jorge Maldonado-Hernández ◽  
Azucena Martínez-Basila ◽  
Mario Enrique Rendón-Macías ◽  
Mardia López-Alarcón

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Erika Ibarra-Pastrana ◽  
Maria del Carmen Candia Plata ◽  
Gerardo Alvarez ◽  
Mauro E. Valencia

Objective. To evaluate the efficacy of the [13C]glucose breath test for measuring insulin resistance in Mexican adults with different glycemic states.Research Design and Methods. Fifty-eight adults underwent a [13C]glucose breath test with simultaneous measurement of total CO2production by indirect calorimetry, at baseline and 90 minutes after the ingestion of 15 g of dextrose and 25 mg of [13C]glucose. HOMA was used as a marker of insulin resistance.Results. We found an inverse correlation between HOMA and the breath testδ13CO2(‰),r=-0.41(P=0.001). After adjusting for total CO2production, correlations between HOMA and fasting glucose were less strong but remained significant. An ROC curve was constructed usingδ13CO2(‰) and HOMA values; the cut-off point was 9.99‰δ13CO2, corresponding to a sensitivity of 80.0 (95% CI: 51.9, 95.7) and a specificity of 67.4 (95% CI: 51.5, 80.9).Conclusions. The [13C]glucose breath test is a simple noninvasive procedure but was not sufficiently robust for an accurate diagnosis of insulin resistance. Our findings suggest that the test might be helpful in identifying individuals who are not IR, which in turn may contribute to improved diabetes prevention.


2013 ◽  
Vol 162 (3) ◽  
pp. 191-200 ◽  
Author(s):  
Ken Tanaka ◽  
Tomokazu Matsuura ◽  
Daisuke Shindo ◽  
Yuta Aida ◽  
Yoshihiro Matsumoto ◽  
...  

RADIOISOTOPES ◽  
2019 ◽  
Vol 68 (2) ◽  
pp. 59-64
Author(s):  
Tomokazu Matsuura ◽  
Hirotaka Ezaki ◽  
Mariko Nakamura ◽  
Yoshihiro Mezaki ◽  
Takahiro Masaki

2014 ◽  
Vol 16 (6) ◽  
pp. 385-391 ◽  
Author(s):  
Jorge Maldonado-Hernández ◽  
Azucena Martínez-Basila ◽  
María Guadalupe Matute-González ◽  
Mardia López-Alarcón

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