scholarly journals Changes in Collagen Type 3, Elastin, Fibrosis and Cajal Cell in Congenital Ureteropelvic Junction Obstruction

2014 ◽  
Vol 1 (1) ◽  
pp. 11-13
Author(s):  
Hasan Deliktaş ◽  
Oktay Issı ◽  
Abdullah Gedik ◽  
Hayrettin Şahin
Keyword(s):  
Ureteropelvic Junction Obstruction ◽  
Collagen Type ◽  
Ureteropelvic Junction ◽  
Type 3 ◽  
Cajal Cell

Relation between Cajal Cell Density and Radiological and Scintigraphic Outcomes in Patients with Ureteropelvic Junction Obstruction

2021 ◽  
pp. 1-6
Author(s):  
Eda Tokat ◽  
Serhat Gurocak ◽  
Ozgur Akdemir ◽  
Ipek Isik Gonul ◽  
Mustafa Ozgur Tan
Keyword(s):  
Cell Density ◽  
Ureteropelvic Junction Obstruction ◽  
Ureteropelvic Junction ◽  
Differential Function ◽  
Cajal Cells ◽  
Significant Difference ◽  
The Mean ◽  
Density Regression ◽  
Cajal Cell

<b><i>Introduction:</i></b> In this study, we aimed to investigate the correlation between Cajal cell density and preoperative and postoperative radiological and scintigraphic parameters in ureteropelvic junction obstruction (UPJO). <b><i>Methods:</i></b> The study group consisted of 41 renal units (38 consecutive patients; 13 female and 25 male) surgically treated for UPJO. UPJ specimens from patients were immuno-stained with CD117 (c-kit) antibody for interstitial Cajal cells (ICCs). The relation between Cajal cell density and preoperative and postoperative radiological and scintigraphic parameters was evaluated. <b><i>Results:</i></b> The mean age of the patients was 8.52 ± 8.86 (0–35) years. The density of Cajal cells was defined in 2 groups for convenient analysis as 0–5 cells (low) in 19 (46.3%) patients and &#x3e;5 cells (moderate-high) in 22 (53.6%). There was significant difference between the preoperative and postoperative anteroposterior diameters of the related kidneys in both Cajal groups (<i>p</i> = 0.001-low, <i>p</i> = 0.000-moderate-high) independent of Cajal cell density. Regression in hydronephrosis postoperatively was determined in both Cajal groups (77.8%-low, 64.7%-moderate-high); however, there was no difference between them (<i>p</i> = 0.39). Preoperative T1/2 was significantly longer in the low Cajal group (<i>p</i> = 0.02). Postoperative T1/2 decreased in both low (<i>p</i> = 0.000) and moderate-high (<i>p</i> = 0.001) Cajal groups, but no difference was found between them (<i>p</i> = 0.24). There was significant improvement in the kidney differential function after surgery in the low Cajal density group (<i>p</i> = 0.015) while there was no correlation between the scintigraphic success or improvement and Cajal cell density (<i>p</i> = 0.51). <b><i>Discussion/Conclusion:</i></b> ICC deficiency/density could not be shown as a predictive factor for the determination of success rate of pyeloplasty. Despite the lack of any evidence for the degree of deficiency as an indicator for the severity of obstruction and prediction of surgical success, further studies are needed for confirmation.

Changes in Cajal cell density in ureteropelvic junction obstruction in children

2016 ◽  
Vol 12 (2) ◽  
pp. 89.e1-89.e5 ◽  
Author(s):  
Cem Senol ◽  
Metin Onaran ◽  
Serhat Gurocak ◽  
Ipek Isık Gonul ◽  
Mustafa Ozgur Tan
Keyword(s):  
Cell Density ◽  
Ureteropelvic Junction Obstruction ◽  
Ureteropelvic Junction ◽  
Cajal Cell

840: Laparoscopic Pyeloplasty for Ureteropelvic Junction Obstruction: Comparing Davinci Robotic to Classic Laparoscopic Pyeloplasty

2005 ◽  
Vol 173 (4S) ◽  
pp. 228-228
Author(s):  
Scott V. Burgess ◽  
Michael M. Woods ◽  
Freddy Mendez-Torres ◽  
Erik P. Castle ◽  
Raju Thomas
Keyword(s):  
Ureteropelvic Junction Obstruction ◽  
Ureteropelvic Junction ◽  
Laparoscopic Pyeloplasty

24: Endopyelotomy for Ureteropelvic Junction Obstruction: What Success Rate can the Patient Expect?

2004 ◽  
Vol 171 (4S) ◽  
pp. 7-7
Author(s):  
Hansjoerg Danuser ◽  
Eduard Dobry ◽  
Fiona C. Burkhard ◽  
Werner W. Hochreiter ◽  
Urs E. Studer
Keyword(s):  
Success Rate ◽  
Ureteropelvic Junction Obstruction ◽  
Ureteropelvic Junction

Outcome of Percutaneous Nephrostomy in Children With Ureteropelvic Junction Obstruction

2020 ◽  
Vol 20 (2) ◽  
pp. 61-64
Author(s):  
Mohammad Mahfuzur Rahman Chowdhury ◽  
Rifat Zaman ◽  
Md Amanur Rasul ◽  
Akm Shahadat Hossain ◽  
Shafiqul Alam Chowdhury ◽  
...  
Keyword(s):  
Renal Function ◽  
Low Dose ◽  
Ureteropelvic Junction Obstruction ◽  
Percutaneous Nephrostomy ◽  
Ureteropelvic Junction ◽  
College Hospital ◽  
Medical College ◽  
Split Renal Function

Introduction and objectives: Congenital ureteropelvic junction obstruction (UPJO) is the most common cause of hydronephrosis. Management protocols are based on the presence of symptoms and when the patient is asymptomatic the function of the affected kidney determines the line of treatment. Percutaneous nephrostomy (PCN) became a widely accepted procedure in children in the 1990s. The aim of the study was to evaluate the results of performing percutaneous nephrostomy (PCN) in all patients with UPJO and split renal function (SRF) of less than 10% in the affected kidney, because the management of such cases is still under debate. Methods:This prospective clinical trial was carried out at Dhaka Medical College Hospital from January 2014 to December 2016. Eighteen consecutive patients who underwent PCN for the treatment of unilateral UPJO were evaluated prospectively. In these children, ultrasonography was used for puncture and catheter insertion. Local anesthesia with sedation or general anesthesia was used for puncture. Pig tail catheters were employed. The PCN remained in situ for at least 4 weeks, during which patients received low-dose cephalosporin prophylaxis. Repeat renography was done after 4 weeks. When there was no significant improvement in split renal function (10% or greater) and PCN drainage (greater than 200 ml per day) then nephrectomies were performed otherwise pyeloplasties were performed. The patients were followed up after pyeloplasty with renograms at 3 months and 6 months post operatively. Results: All the patients had severe hydronephrosis during diagnosis and 14 patients with unilateral UPJO were improved after PCN drainage and underwent pyeloplasty. The rest four patients that did not show improvement in the SRF and total volume of urine output underwent nephrectomy. In the patients with unilateral UPJO who improved after PCN drainage, the SRF was increased to 26.4% ±8.6% (mean± SD) after four weeks and pyeloplasty was performed. At three and six months follow-up, SRF value was 29.2% ±8.5% and 30.8.2% ±8.8% respectively. Conclusion: Before planning of nephrectomy in poorly functioning kidneys (SRF < 10%) due to congenital UPJO, PCN drainage should be done to asses improvement of renal function. Bangladesh Journal of Urology, Vol. 20, No. 2, July 2017 p.61-64

PEMERIKSAAN RADIOLOGIS URETEROPELVIC JUNCTION OBSTRUCTION PADA ANAK

2020 ◽  
Vol 4 (1) ◽  
pp. 18-25
Author(s):  
Yarmaniani Miliati Muchtar ◽  
Bambang Soeprijanto ◽  
Indrastuti Normahayu ◽  
Lenny Violetta
Keyword(s):  
Early Detection ◽  
Ureteropelvic Junction Obstruction ◽  
Radiological Examination ◽  
Ureteropelvic Junction ◽  
Common Cause

Ureteropelvic junction obstruction ( UPJO ) is the most common cause of hydronephrosis in children. Hydronephrosis caused by prolongedUPJO will damaged the kidneys. Early detection needed to avoid the complication. In fact, there are cases which is discovered in older child.Therefore it is necessary to carry out appropriate diagnostic steps and support the management of patients. Radiological examination usingvarious modalities can help diagnose UPJO.

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