Effects of Paracetamol and Tenoxicam on Postoperative Pain and Need for Rescue Analgesia in Root Canal Treatments Performed Under General Anesthesia: A Retrospective Study

Abstract BackgroundThe present study aimed to compare the safety and efficacy of intravenous oxycodone with fentanyl in geriatric patients undergoing general anesthesia for ophthalmic surgeries.Methods107 geriatric patients (age 65-79 years old) with the ASA physical status 1 or 2 undergoing general anesthesia for glaucoma or retina surgeries between May 2016 and November 2017 were divided into three groups: Group O1, Group O2, and Group F. After exclusion, 105 patients were included for the final analysis, with 35 patients in each group. Oxycodone (0.1 mg/kg in Group O1, or 0.2 mg/kg in Group O2) or fentanyl (2 mcg/kg in Group F) was administered intravenously during induction of general anesthesia. Patient demographics, surgical time and anesthesia time, perioperative hemodynamic parameters and requirement of vasoactive medication, postoperative pain and requirement of rescue analgesics, postoperative sedation level and recovery time, and perioperative complications were recorded.ResultsPatients in Group O1 experienced less clinically significant hypotension compared to either Group F or Group O2. Consistently, patients in Group O1 required less intraoperative vasoactive medication (ephedrine) than those in Group F. The postoperative pain on extubation was more severe and more patients required rescue analgesia in Group F compared to Group O2, but not Group O1. The recovery time was longer and sedation level was higher in Group O2 than Group F or O1. The incidence of hypoxia during postoperative recovery was higher in Group O2 than Group F or O1.ConclusionOxycodone at 0.1mg/kg can be a safe and effective application for geriatric patients undergoing general anesthesia for ophthalmic surgeries, with adequate pain control and less side effects.

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Effect of preoperative anxiety, depression, and insomnia on acute postoperative pain after non-cardiac surgery

10.21203/rs.3.rs-429163/v1 ◽

2021 ◽

Author(s):

Dandan Lin ◽

Xiao Huang ◽

Jing Wang ◽

Yanan Hao ◽

Mengwen Geng ◽

...

Keyword(s):

Cardiac Surgery ◽

Retrospective Study ◽

Postoperative Pain ◽

Mental Disease ◽

Disease Group ◽

Acute Postoperative Pain ◽

Rescue Analgesia ◽

Mental Diseases ◽

Vas Scores ◽

Anxiety Depression

Abstract Background The mental diseases especially anxiety, depression, and insomnia are common in patients at perioperative period. This study aims to investigate the association of preoperative mental diseases with acute postoperative pain of patients undergoing non-cardiac surgery. Method: The patients undergoing non-cardiac surgery from August 1, 2019 to January 23, 2020 at Capital Medical University, Beijing Chao-Yang Hospital were included in this retrospective study. The demographics, clinical data and assessments of depression, anxiety, and insomnia by Insomnia Severity Index (ISI), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) were collected and analyzed. The patients with any of depression, anxiety or insomnia were divided into mental disease group, and others were in non-mental disease group according to the. We compared the postoperative visual analog score between patients in mental diseases group with propensity score matching cohort from patients in non-mental diseases. The primary outcome was acute postoperative pain according to the Visual Analog Scale (VAS) 24h after surgery. Secondary outcomes included VAS at other time points and incidence of postoperative nausea and vomiting (PONV), rescue analgesia, and length of hospital stay (LOS). Results The analysis included 397 patients (274 in the group and 123 in the mental disease group). Patients in mental disease group (anxiety, depression and insomnia) were associated with higher VAS scores and increased times of rescue analgesia. Each of the 3 mental diseases was associated with higher VAS scores independently. Conclusion In this retrospective study, preoperative anxiety, depression and insomnia were associated with increased the level of acute postoperative pain and increased times of rescue analgesia of patients undergoing non-cardiac surgery.

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Safety and efficacy of intravenous oxycodone in geriatric patients undergoing general anesthesia for ophthalmic surgeries:a randomized controlled trial

10.21203/rs.2.13244/v1 ◽

2019 ◽

Author(s):

Shuangshuang Li ◽

Dongdong Yao ◽

Xiao Hu ◽

Wenxian Li ◽

Fang Tan

Keyword(s):

Postoperative Pain ◽

General Anesthesia ◽

Recovery Time ◽

Geriatric Patients ◽

Perioperative Complications ◽

Controlled Trial ◽

Rescue Analgesia ◽

Safety And Efficacy ◽

Sedation Level ◽

Vasoactive Medication

Abstract Abstract Background: The present study aimed to compare the safety and efficacy of intravenous oxycodone with fentanyl in geriatric patients undergoing general anesthesia for ophthalmic surgeries. Methods: 107 geriatric patients (age 65-79 years old) with the ASA physical status 1 or 2 undergoing general anesthesia for glaucoma or retina surgeries between May 2016 and November 2017 were divided into three groups: Group O1, Group O2, and Group F. After exclusion, 105 patients were included for the final analysis, with 35 patients in each group. Oxycodone (0.1 mg/kg in Group O1, or 0.2 mg/kg in Group O2) or fentanyl (2 mcg/kg in Group F) was administered intravenously during induction of general anesthesia. Patient demographics, surgical time and anesthesia time, perioperative hemodynamic parameters and requirement of vasoactive medication, postoperative pain and requirement of rescue analgesics, postoperative sedation level and recovery time, and perioperative complications were recorded. Results: Patients in Group O1 experienced less clinically significant hypotension compared to either Group F or Group O2. Consistently, patients in Group O1 required less intraoperative vasoactive medication (ephedrine) than those in Group F. The postoperative pain on extubation was more severe and more patients required rescue analgesia in Group F compared to Group O2, but not Group O1. The recovery time was longer and sedation level was higher in Group O2 than Group F or O1. The incidence of hypoxia during postoperative recovery was higher in Group O2 than Group F or O1. Conclusion: Oxycodone at 0.1mg/kg can be a safe and effective application for geriatric patients undergoing general anesthesia for ophthalmic surgeries, with adequate pain control and less side effects. Trial registration: The study was registered at http://www.chictr.org.cn , Clinical Trial Number: ChiCTR-IPR-16007927. Date of registration: February 15, 2016. Keywords: Oxycodone, Fentanyl, Geriatric, Ophthalmology, General anesthesia

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Faculty Opinions recommendation of Regional versus general anesthesia and the incidence of unplanned health care resource utilization for postoperative pain after wrist fracture surgery: results from a retrospective quality improvement project.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726000784.793518000 ◽

2016 ◽

Author(s):

Jan Jakobsson

Keyword(s):

Health Care ◽

Quality Improvement ◽

Postoperative Pain ◽

General Anesthesia ◽

Resource Utilization ◽

Wrist Fracture ◽

Health Care Resource ◽

Improvement Project ◽

Health Care Resource Utilization ◽

Fracture Surgery

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Clinical and radiographic outcome of the root canal treatment of infected teeth with associated sinus tract: A retrospective study

Australian Endodontic Journal ◽

10.1111/aej.12526 ◽

2021 ◽

Author(s):

Liliana Artaza ◽

Andrea Campello ◽

Giuliana Soimu ◽

Flávio R. F. Alves ◽

Isabela N. Rôças ◽

...

Keyword(s):

Retrospective Study ◽

Root Canal ◽

Sinus Tract ◽

Root Canal Treatment ◽

Radiographic Outcome

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Impact on Quality of Life of Patients Treated by Different File Systems for Root Canal Treatment

Journal of Health and Allied Sciences NU ◽

10.1055/s-0040-1722108 ◽

2021 ◽

Author(s):

L.S. Priyanka ◽

Lakshmi Nidhi Rao ◽

Aditya Shetty ◽

Mithra N. Hegde ◽

Chitharanjan Shetty

Keyword(s):

Quality Of Life ◽

Oral Health ◽

Postoperative Pain ◽

Root Canal ◽

File Systems ◽

Study Groups ◽

Significant Difference ◽

Related Quality ◽

The Impact

Abstract Introduction The outcomes of oral health conditions and therapy for those conditions are described by the term “oral health-related quality of life.” Oral health-related quality of life is recognized by the World Health Organization as an important part of the Global Oral Health Program. The study aims to compare the impact of three root canal preparation systems on patients’ quality of life and correlate postoperative pain with the impact on the quality of life. Materials and Methods A survey was performed in which 90 patients were randomly assigned to three groups based on the root canal preparation system: (1) ProTaper Gold (Dentsply, Tulsa Dental Specialties, Tulsa, Oklahoma, United States), (2) Neoendo flex (Neoendo, India),and (3) Hyflex EDM/CM (Coltene Whaledent) that included 30 participants in each group. Data collection included the implementation of a demographic data questionnaire, Oral Health Impact Profile 14 (quality of life), and visual analogue scale(pain). The questionnaire was given after root canal treatment in the first 24 hours. The data obtained were statistically analyzed. Results No significant differences were found in the quality of life among study groups. Group 1 demonstrated a highly significant difference in the postoperative pain with p value of 2.67. Conclusion Within the limitations of the present study, Protaper Gold showed a highly significant difference in postoperative pain when compared with other file systems. No significant differences were found in the quality of life among the study groups.

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Comparison of the Effects of a Bioceramic and Conventional Resin-Based Sealers on Postoperative Pain after Nonsurgical Root Canal Treatment: A Randomized Controlled Clinical Study

Materials ◽

10.3390/ma14102661 ◽

2021 ◽

Vol 14 (10) ◽

pp. 2661

Author(s):

Kiche Shim ◽

Young-Eun Jang ◽

Yemi Kim

Keyword(s):

Postoperative Pain ◽

Postoperative Period ◽

Root Canal ◽

Continuous Wave ◽

Root Canal Treatment ◽

Root Canals ◽

Anterior Teeth ◽

Significant Difference ◽

Ah Plus ◽

Group 2

Background: This clinical trial aimed to compare the effects of bioceramic sealer and resin-based sealer on the incidence and intensity of postoperative pain. Methods: Patients with anterior teeth or premolars requiring root canal treatment were assigned to group 1 (n = 51). Those with molars requiring treatment were assigned to group 2 (n = 57). In groups 1En and 2En, root canals were obturated with Endoseal MTA using the single-cone technique. In groups 1AH and 2AH, the sealer used was AH Plus with the continuous wave technique. On the day of canal filling, each patient was instructed to indicate their pain intensity over the 7 day postoperative period, at rest and, while biting, using a visual analog scale. Results: There was no significant difference in the incidence or intensity of postoperative pain between the Endoseal MTA and AH Plus groups during the 7 day postoperative period (p > 0.05). Less time was needed to seal the root canals with Endoseal MTA, especially in group 2 (p < 0.05). Conclusions: Endoseal MTA and AH Plus had similar effects on the incidence and intensity of postoperative pain. The obturation time was shorter when using Endoseal MTA compared to AH Plus.

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A retrospective study of electroencephalography burst suppression in children undergoing general anesthesia

Pediatric Investigation ◽

10.1002/ped4.12287 ◽

2021 ◽

Author(s):

Zhengzheng Gao ◽

Jianmin Zhang ◽

Xiaoxue Wang ◽

Mengnan Yao ◽

Lan Sun ◽

...

Keyword(s):

Retrospective Study ◽

General Anesthesia ◽

Burst Suppression

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Incorporation of an intercostal catheter into a multimodal analgesic strategy for uniportal video-assisted thoracoscopic surgery: a feasibility study

Journal of Cardiothoracic Surgery ◽

10.1186/s13019-021-01590-z ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Jian Wei Tan ◽

Jameelah Sheik Mohamed ◽

John Kit Chung Tam

Keyword(s):

Postoperative Pain ◽

Length Of Stay ◽

Urinary Retention ◽

Feasibility Study ◽

Thoracoscopic Surgery ◽

Early Recovery ◽

Rescue Analgesia ◽

Video Assisted ◽

Pain Scores ◽

Video Assisted Thoracoscopic Surgery

Abstract Background Well-controlled postoperative pain is essential for early recovery after uniportal video-assisted thoracoscopic surgery (UVATS). Conventional analgesia like opioids and thoracic epidural anaesthesia have been associated with hypotension and urinary retention. Intercostal catheters are a regional analgesic alternative that can be inserted during UVATS to avoid these adverse effects. This feasibility study aims to evaluate the postoperative pain scores and analgesic requirements with incorporation of an intercostal catheter into a multimodal analgesic strategy for UVATS. Methods In this observational study, 26 consecutive patients who underwent UVATS were administered a multilevel intercostal block and oral paracetamol. All of these patients received 0.2% ropivacaine continuously at 4 ml/h via an intercostal catheter at the level of the incision. Rescue analgesia including etoricoxib, gabapentin and opioids were prescribed using a pain ladder approach. Postoperative pain scores and analgesic usage were assessed. The secondary outcomes were postoperative complications, days to ambulation and length of stay. Results No technical difficulties were encountered during placement of the intercostal catheter. There was only one case of peri-catheter leakage. Mean pain score was 0.31 (range 0–2) on post-operative day 1 and was 0.00 by post-operative day 5. 16 patients (61.6%) required only oral rescue analgesia. The number of patients who required rescue non-opioids only increased from 1 in the first 7 months to 8 in the next 7 months. There were no cases of hypotension or urinary retention. Median time to ambulation was 1 day (range 1–2). Mean post-operative length of stay was 4.17 ± 2.50 days. Conclusions Incorporation of an intercostal catheter into a multimodal analgesia strategy for UVATS is feasible and may provide adequate pain control with decreased opioid usage.

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