scholarly journals Seminal Fluid Analysis And Biophysical Profile: Findings And Relevance In Infertile Males In Ilorin, Nigeria

2004 ◽  
Vol 5 (3) ◽  
Author(s):  
EK Oghagbon ◽  
AAG Jimoh ◽  
SA Adebisi
Keyword(s):  
Seminal Fluid ◽  
Fluid Analysis ◽  
Biophysical Profile

Seminal Fluid Analysis and Sperm Function Testing

1994 ◽  
Vol 23 (4) ◽  
pp. 725-748 ◽  
Author(s):  
D. Stewart Irvine ◽  
R. John Aitken
Keyword(s):  
Seminal Fluid ◽  
Sperm Function ◽  
Fluid Analysis ◽  
Function Testing

scholarly journals Relationship Between Post-Pubertal Mumps Infection In Males With Infertilityand Its Effect on The Result of Seminal Fluid Analysis and Occurrence of Immunological Infertility

2020 ◽  
Vol 19 (2) ◽  
pp. 118-128
Author(s):  
Sahar Mohammed Zaki Abdullah ◽  
Keyword(s):  
Seminal Fluid ◽  
Testicular Atrophy ◽  
Enzyme Linked Immunosorbent Assay ◽  
Adult Males ◽  
Cross Sectional ◽  
Fluid Analysis ◽  
Immunological Infertility ◽  
History Of ◽  
Sperm Antibodies ◽  
Mumps Infection

Background: Mumps caused by paramyxovirus in the same group as parainfluenza and Newcastle disease virus, orchitis is the widely recognized complication in post-pubertal males. Approximately 50% of patients with orchitis have some degree of testicular atrophy, but sterility is rare. Objective: To demonstrate the effect of the post-pubertal mumps infection on the result of seminal fluid analysis and to know if infection by mumps after puberty can lead to immunological infertility and production of anti-sperm antibodies. Patients and Methods: Cross-sectional study in which 300 infertile males attending microbiology laboratory in Rizgary teaching hospital in Erbil city in Iraqi Kurdistan from November 2017- September 2018. Questionnaire was prepared for each male which included: name, age, occupation, history of mumps infection after puberty. Seminal fluid collected from each patient after 3 days of abstinence and analyzed according to WHO guidelines. Seminal fluid and serum obtained from each infertile male for the detection of anti-sperm antibodies by ELISA (enzyme-linked immunosorbent assay). Results: The mean age of the participant in the study was (32.805 year) with the maximum and minimum age was (50, 18) years respectively. The incidence of post-pubertal mumps was (13.3%) and the incidence of abnormal seminal fluid analysis was (10%) and the highest abnormal seminal fluid variables among infertile males with post-pubertal mumps was oligoasthenozoospermia (43%) and the anti-sperm antibodies in the semen of infertile males with post-pubertal mumps infection was (60%) while the frequency of anti-sperm antibodies in the serum in infertile males with a history of post-pubertal mumps was (40%) which was higher than those with no history of post-pubertal mumps with highly significant relation statistically. Conclusion: Abnormal seminal fluid analysis result may be due to post-pubertal mumps and it can lead to (Asthenozoospermia, Oligospermia, and Teratozoospermia). The highest percentage of abnormal seminal fluid variables was Oligoasthenozoospermia the occurrence of anti-sperm antibodies can be the sequence of post-pubertal mumps and by itself can lead to abnormality in the seminal fluid analysis. Mumps can lead to male infertility by affecting the seminal fluid parameters and also by the production of anti-sperm antibodies which can lead to subfertility in adult males. Keywords: Paramyxovirus, post-pubertal mumps, anti-sperm antibodies

Seminal fluid analysis changes after testicular varicocelectomy in a sample of Iraqi patients

2021 ◽  
Vol 3 (1) ◽  
pp. 13-25
Author(s):  
Anwar Majed ◽  
Manal Rasheed ◽  
Mohammed Jasim
Keyword(s):  
Seminal Fluid ◽  
Sperm Count ◽  
Semen Analysis ◽  
Statistical Significance ◽  
Sperm Concentration ◽  
P Value ◽  
Factors Affecting ◽  
Fluid Analysis ◽  
Medical City ◽  
Fluid Parameters

Background: Semen analysis measures ejaculate volume, pH, sperm count, motility, forward progression, and morphology. Although semen analysis is not a test for infertility, it is considered the most important laboratory test in the evaluation of male fertility. There are many factors affecting the seminal fluid parameters and testicular varicocele is one of them. Varicoceles are the most commonly seen and correctable male infertility factor. Varicocelectomy is a common operation performed for infertile males with clinical varicocele. The aim of study to evaluate the seminal fluid parameters changes after testicular varicocelectomy. Patients and Method: A prospective cohort study was done at the Al Sader Medical City in Najaf during the period from (March-October 2019). The study include 30 males with age between 18 and 32 years old who had a clinical varicocele. Seminal fluid analysis was done one before surgery and another one three months after surgery and compare between the two tests to evaluate the changes in the parameters was done, which include seminal fluid liquefaction, volume, color, PH, sperm concentration, motility and morphology. Results: There were 30 patients enrolled in this study with a mean age of 23.8 ± 3.36. Seminal fluid concentration was 19.1 ± 7.2 million/ml and it was significantly increased postoperatively by almost 84% than preoperative concentration to reach 35.1 ± 11.3 (P ≤ 0.001). The changes in progressive motile sperms’ percent improved after varicocelectomy but not reach the statistical significance (P≥0.935). The mean ± SD percent of normal morphology sperms percent preoperatively was 46.9 ± 22.9 %, and after operation, it elevated to 50.9 ± 18.6 (p value≥ 0.336 ).The patients is divided in to two subgroups (normospermic and oligospermic subgroup). Conclusion: There is a significant improvement in sperm concentration. While there is significant improvement in sperm concentration in oligospermic subgroup, so the infertile patient who has oligospermia with varicocele will get better outcome after varicocelectomy. Keywords: Seminal fluid, analysis changes, testicular varicocelectomy.

The effect of Cannabis sativa on testosterone level and seminal fluid analysis of male Wistar rats

2008 ◽  
Vol 3 (2) ◽  
pp. 223-226
Author(s):  
E.K. Nwangwa ◽  
Q.e. Arigi ◽  
A.O. Naiho ◽  
E. Jeroh
Keyword(s):  
Testosterone Level ◽  
Wistar Rats ◽  
Cannabis Sativa ◽  
Seminal Fluid ◽  
Fluid Analysis ◽  
Male Wistar Rats

Seminal fluid analysis and testicular volume in adults with epilepsy receiving valproate

2015 ◽  
Vol 22 (3) ◽  
pp. 508-512 ◽  
Author(s):  
Sherifa A. Hamed ◽  
Ehab M.M. Moussa ◽  
Amal M. Tohamy ◽  
Khaled O. Mohamed ◽  
Mohamad E. Mohamad ◽  
...  
Keyword(s):  
Seminal Fluid ◽  
Testicular Volume ◽  
Fluid Analysis

scholarly journals Evaluation of sex hormone profiles and seminal fluid analysis in psoriatic patients and their correlation with psoriasis severity

2021 ◽  
Keyword(s):  
Sexual Dysfunction ◽  
Seminal Fluid ◽  
Sperm Concentration ◽  
Sex Hormone ◽  
Case Group ◽  
Healthy Controls ◽  
Hormonal Profile ◽  
Fluid Analysis ◽  
Normal Sperm ◽  
The Mean

Background and objective: Psoriasis is a chronic inflammatory skin condition characterized by thick silvery plaques, commonly involving the elbow, knees, lower back, and scalp. Psoriasis also affects the reproductive systems of patients. Males with untreated psoriasis are at risk of impaired fertility due to chronic systemic inflammation, which might affect the hormonal profile and sexual accessory glands. In females, having psoriasis does not affect the chances of getting pregnant. This study aims to assess the effect of psoriasis, as a chronic inflammatory condition, on sex hormone profiles and seminal fluid parameters. Methods: 87 male patients aged 18−50 with psoriasis who fulfilled the inclusion criteria were included in the study and matched with healthy controls. Demographic and clinical data, including age, severity, duration, and body mass index (BMI) were recorded. All patients underwent a complete physical exam, including a skin and andrological exam, in addition to ultrasound scrotum and seminal fluid analysis. Blood sample tests were conducted for a complete hormonal profile, including luteinizing hormone (LH), follicular stimulating hormone (FSH), testosterone, and estradiol. Results: The mean age of the case group was 39.5 ± 5.6 years, and the mean BMI was 24.0 ± 2.2. The mean duration of psoriasis was 6.5 ± 3.5 years. The mean levels of testosterone and LH of cases were lower than those of controls, whereas FSH and estradiol were abnormally higher among case groups. Sperm concentration, normal sperm motility, and normal sperm morphology were also found to be lower than in the case group. Age, psoriasis area, and severity index (PASI) scores were significant predictors of sperm concentration (P = 0.000). The BMI was negatively correlated with sperm concentration (−0.249, P = 0.01), motility (−0.198, P = 0.05), and morphology (−0.205, P = 0.05). A negative correlation was found between the PASI score and sperm concentration (−0.519, P = 0.01). Conclusion: The evaluation of seminal fluid analysis and hormone profiles among psoriasis patients showed marked variability. However, it was evident that the levels of sex hormones and seminal parameters were lower among patients with psoriasis than the healthy controls; this may indicate the possibility of developing sexual dysfunction and infertility among patients with untreated psoriasis. The level of estradiol was found to be abnormally high among psoriasis cases, which may account for a possible compensatory mechanism in ongoing sexual dysfunction among psoriasis patients.

scholarly journals Lactate dehydrogenase C4 (LDH-C4) is essential for the sperm count and motility: A case-control study

2021 ◽  
Vol 2 (03) ◽  
pp. 152-165
Author(s):  
Baraa Saeed ◽  
Rayah Baban ◽  
Usama Al-Nasiri
Keyword(s):  
Lactate Dehydrogenase ◽  
Kinetic Parameters ◽  
Seminal Fluid ◽  
Sperm Count ◽  
Maximum Velocity ◽  
Fluid Analysis ◽  
Infertile Men ◽  
Km Value ◽  
Motility Of Sperm ◽  
Important Enzyme

Background: The lactate dehydrogenase C4 (LDH-C4) isoenzyme is an important enzyme involved in metabolic processes that are needed for spermatogenesis and sperm motility. Objectives: This study aims to assess the activity and kinetic parameters (maximum velocity, Vmax and Michaelis constant, Km) of LDH-C4 in fertile and infertile (azoospermia and oligospermia) men in Baghdad City, Iraq. Methods: A total of 120 participants (80 infertile and 40 healthy fertile men) were included in the current study. The patients were sub-grouped into: 40 infertile men with oligospermia, and 40 infertile men with azoospermia. The oligospermia patients were further subdivided into subgroups based on sperm count and motility. Semen samples were obtained by masturbation after 3-5 days abstain for seminal fluid analysis. The microscopic test included the assessment of the count, motility and morphology of the sperms. In addition, the coulometric assay was used for measuring the activity and kinetic parameters of LDH-C4 enzyme. Results: The activity of LDH-C4 is significantly higher in fertile men when compared with infertile subjects (fertile: 403.13±189.90, oligospermia: 110.01±58.13, azoospermia: 39.06±28.15; p≤0.01). Statistically significant differences in LDH-C4 activity were also noted among patients with oligospermia based on sperms count and motility. Based on sperms’ count in patients with oligospermia, a significantly higher LDH-C4 activity (p≤0.01) was noted in those with higher sperm count (10-15 million/ml) when compared to others who have lesser count. Significant elevation in enzyme activity (p≤0.01) was also observed in oligospermia patients with higher percentages of motile sperms when compared with others who have fewer percentages of motile sperms. Moreover, the highest Vmax value (0.483 mmol/L.min) and the lowest Km value (0.39 mmol/L.min) were recorded in fertile men. While, the lowest Vmax value (0.174 mmol/L.min) and the lowest Km value (0.75 mmol/L.min) were detected in azoospermia patients. Conclusions: Our results suggest that LDH-C4 is essential for the count and motility of sperm and may be considered as a therapeutic approach for infertility.

scholarly journals Sperm DNA Fragmentation Among Smokers and Non-Smokers as Measured by Sperm Chromatin Dispersion Test

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Azha Syahril Azizan ◽  
Kamarul Bahyah Mustafa ◽  
Azantee Yazmie Abdul Wahab ◽  
Roszaman Ramli ◽  
Nurkhairulnisa Abu Ishak
Keyword(s):  
Dna Fragmentation ◽  
Seminal Fluid ◽  
Sperm Concentration ◽  
Sperm Chromatin ◽  
Sperm Dna Fragmentation ◽  
Cross Sectional ◽  
Fluid Analysis ◽  
Sperm Dna ◽  
Dispersion Test ◽  
Sperm Chromatin Dispersion Test

Introduction: Traditionally, seminal fluid analysis is done to assess male infertility particularly sperm concentration, morphology and motility. Sperm chromatin dispersion test explores the quality of the sperm DNA structures. High sperm DNA fragmentation is associated with unexplained infertility, failure of assisted reproduction and recurrent miscarriages. Smoking has been associated with high sperm DNA fragmentation in some studies but not in others. Materials and Methods: A comparative cross-sectional study, involving 32 smokers and 32 non-smokers to determine the association between cigarette smoking and sperm DNA fragmentation. Semen samples were collected from patients undergoing seminal fluid analysis (SFA) at the IIUM Fertility Centre and IIUM Medical Centre O&G Clinic from January 2017 to June 2018. Sperm chromatin dispersion test was done and level of 15% is considered upper limit of normal. Results: 53.1% in the smoker group have abnormal level of sperm DNA fragmentation compared to 34.4% of nonsmokers. The median and interquartile range for smokers were 15.30 and 19.0 (10.425 - 29.375) respectively while for non-smokers were 8.25 and 17.8 (4.075 - 21.850) which was statistically significant (p= 0.012). It was also noted that three participants in the smoker group (9.4%) has very high sperm DNA fragmentation index of more than 80% even though they have normal seminal fluid analysis. Conclusion: There is an association between smoking and high sperm DNA fragmentation. There is a trend of increased in DNA fragmentation in smokers even though their SFA results were normal.

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