The selection of the optimal target population for spiral CT screening and chemoprevention trials

2010 ◽  
pp. 361-384
Author(s):  
Rob J van Klaveren ◽  
Fred R Hirsch ◽  
Carola A van lersel ◽  
Paul A Bunn
Keyword(s):  
Spiral Ct ◽  
Target Population ◽  
Ct Screening ◽  
Optimal Target ◽  
Selection Of

Lung cancer screening by spiral CT. What is the optimal target population for screening trials?

Lung Cancer ◽  
2002 ◽  
Vol 38 (3) ◽  
pp. 243-252 ◽  
Author(s):  
Rob J van Klaveren ◽  
Harry J de Koning ◽  
James Mulshine ◽  
Fred R Hirsch
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Lung Cancer Screening ◽  
Spiral Ct ◽  
Target Population ◽  
Optimal Target ◽  
Screening Trials

scholarly journals The therapeutic mechanism of epilepsy seizures in different target areas: Research on a theoretical model

2021 ◽  
Vol 29 ◽  
pp. 455-461
Author(s):  
Bing Hu ◽  
Zhizhi Wang ◽  
Minbo Xu ◽  
Luyao Zhu ◽  
Dingjiang Wang
Keyword(s):  
Pyramidal Neurons ◽  
Control Mechanism ◽  
Difficult Problem ◽  
Calculation Model ◽  
Thalamic Reticular Nucleus ◽  
Reticular Nucleus ◽  
Theoretical Support ◽  
Therapeutic Mechanism ◽  
Optimal Target ◽  
Selection Of

BACKGROUND: The selection of optimal target areas in the surgical treatment of epilepsy is always a difficult problem in medicine. OBJECTIVE: We employed a theoretical calculation model to explore the control mechanism of seizures by an external voltage stimulus acting in different nerve nuclei. METHODS: Theoretical analysis and numerical simulation were combined. RESULTS: The globus pallidus, excitatory pyramidal neurons, striatal D1 neurons, thalamic reticular nucleus and specific relay nuclei were selected, we analyzed that the electrical stimulation has different effects in these target areas. CONCLUSIONS: The data selected were reasonable in study, the results may give a theoretical support for similar studies in clinical.

Economic selection of optimal target values

2000 ◽  
Vol 11 (5) ◽  
pp. 369-381 ◽  
Author(s):  
M.A. Rahim ◽  
A.-B. Shaibu
Keyword(s):  
Target Values ◽  
Optimal Target ◽  
Economic Selection ◽  
Selection Of

Detection Failures in Spiral CT Screening for Lung Cancer: Analysis of CT Findings

Radiology ◽  
1999 ◽  
Vol 212 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Ryutaro Kakinuma ◽  
Hironobu Ohmatsu ◽  
Masahiro Kaneko ◽  
Kenji Eguchi ◽  
Tsuguo Naruke ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Spiral Ct ◽  
Ct Screening ◽  
Ct Findings

LONGITUDINAL, QUANTITATIVE EVALUATION OF EMPHYSEMATOUS CHANGES AS SHOWN BY LOW-DOSE SPIRAL CT SCREENING IMAGES AMONG SMOKERS

CHEST Journal ◽  
2006 ◽  
Vol 130 (4) ◽  
pp. 85S
Author(s):  
Takeshi Nawa ◽  
Suzushi Kusano ◽  
Toru Nakagawa ◽  
Masataka Irokawa ◽  
Yuji Oka
Keyword(s):  
Quantitative Evaluation ◽  
Low Dose ◽  
Spiral Ct ◽  
Ct Screening

scholarly journals Design of an Exoskeleton Prototype for Shoulder Rehabilitation

2017 ◽  
Author(s):  
◽  
D. Sosa-Méndez
Keyword(s):  
External Rotation ◽  
Adult Population ◽  
Target Population ◽  
Stress And Strain ◽  
Element Analysis ◽  
Motor Disability ◽  
Shoulder Flexion ◽  
Flexion Extension ◽  
Robotic Devices ◽  
Selection Of

The motor disability is a problem at the global level and according to the census 2010 from INEGI, in Mexico, people with mobility problems represent 58.3 % of the population with disabilities. To face this problem, robotic devices for rehabilitation have emerged which allow to perform therapies with accuracy, efficiency, reduction of physical efforts and the opportunity to perform them in group. However, these devices may not match the mobility of the members to rehabilitate and their adaptation to the mexican anthropometry is limited. In this article, the design of an exoskeleton focused on the Mexican adult population with partial loss of mobility in the shoulder is presented. The objective is to develop an exoskeleton capable of generating the 3 basic movements of the shoulder (flexion-extension, abduction-adduction and internal-external rotation) considering the anthropometric measurements of the target population. For the design of the prototype, an adaptation of the mechatronic design methodology for robots is used. The proposed design is validated kinematically through numerical simulations in Matlab® and ADAMS™, the numerical results prove the range of mobility of each exoskeleton joint. Moreover, a finite element analysis is carried out to quantify the stress and strain levels in the exoskeleton, verifying the selection of materials for its manufacture.

Using a National Register as a Sampling Frame from the Perspective of an Early Career Researcher

2019 ◽  
Vol 5 (1) ◽  
pp. 92-93
Author(s):  
A. Callanan
Keyword(s):  
Representative Sample ◽  
Target Population ◽  
Early Career ◽  
Sampling Frame ◽  
National Register ◽  
Advantages And Disadvantages ◽  
Early Career Researcher ◽  
Nationally Representative ◽  
General Dentists ◽  
Selection Of

Background: Selection of a sampling frame is a key component of conducting survey-based research. This article discusses the use of a national register, the Dental Register, as a sampling frame from the perspective of an early career researcher. Methods: While conducting a survey-based study of a nationally representative sample of general dentists in Ireland, I documented the difficulties I encountered while using a national register. As a research assistant and novice researcher, I recorded the advantages and disadvantages I discovered over the course of the project and its impact on the study. Conclusion: While using a national register has advantages such as a readily available sample of the target population, there are also inherent disadvantages depending on the manner in which records are recorded. Knowledge Transfer Statement: This article can be used as an informative guide to researchers in selecting a sampling frame, with particular emphasis on the use of a national register in selecting a nationally representative sample of dentists.

scholarly journals The Double Burden of Malnutrition: A Systematic Review of Operational Definitions

2020 ◽  
Vol 4 (9) ◽  
Author(s):  
Jennie N Davis ◽  
Brietta M Oaks ◽  
Reina Engle-Stone
Keyword(s):  
Target Population ◽  
Micronutrient Deficiency ◽  
Health Priorities ◽  
Double Burden ◽  
Global Consensus ◽  
Future Assessment ◽  
Frequency Of Use ◽  
Fit For Purpose ◽  
Double Burden Of Malnutrition ◽  
Selection Of

ABSTRACT Background Despite increasing research on the double burden of malnutrition (DBM; i.e., coexisting over- and undernutrition), there is no global consensus on DBM definitions. Objectives To identify published operational DBM definitions, measure their frequency of use, and discuss implications for future assessment. Methods Following a structured search of peer-reviewed articles with terms describing “overnutrition” [e.g., overweight/obesity (OW/OB)] and “undernutrition” (e.g., stunting, micronutrient deficiency), we screened 1920 abstracts, reviewed 500 full texts, and extracted 623 operational definitions from 239 eligible articles. Results We organized three identified DBM dimensions (level of assessment, target population, and forms of malnutrition) into a framework for building operational DBM definitions. Frequently occurring definitions included coexisting: 1) OW/OB and thinness, wasting, or underweight (n = 289 occurrences); 2) OW/OB and stunting (n = 161); 3) OW/OB and anemia (n = 74); and 4) OW/OB and micronutrient deficiency (n = 73). Conclusions Existing DBM definitions vary widely. Putting structure to possible definitions may facilitate selection of fit-for-purpose indicators to meet public health priorities.

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