scholarly journals Bilateral Bizarre Vulvar Swellings in a Teenager: A very rare Entity of Aggressive Angiomyxoma

2020 ◽  
Vol 3 (3) ◽  
pp. 82-88
Author(s):  
Rana Tashhir ◽  
◽  
Yasin Abeer ◽  

Background: Aggressive angiomyxoma (AA) is a rare mesenchymal neoplasm that commonly occurs in perineal region of females. Case Report: A 17 years female presents with bilateral bizarre vulvar swellings, gradually increasing in size for 2 years, painful for 1 week. Sonographic evaluation revealed bilateral well-defined hypoechoic lesions with internal vascularity and cystic areas. Magnetic resonance imaging (MRI) demonstrated these lesions to be iso-intense to skeletal muscles on T1-weighted images (T1WI) and hyperintense on T2-weighted images (T2WI). These were surgically excised and sent for histopathology that confirmed these lesions to be AA. Discussion: AA is an uncommon neoplasm of mesenchymal origin that arises mainly in the perineal soft tissue of adults. It occurs predominantly in females with a peak incidence in fourth decade. [1] In our case the patient was a teenager. In females it may present as a vulvar nodule, polyp or may even be mistaken for a Bartholin’s or labial cyst. In males it involves analogous sites including inguino-scrotal region. [4] Most of the reported cases include solitary unilateral lesions. Conclusion: Our case is unique because the patient was in her teenage and presented with bilateral vulvar angiomyxomas that showed internal vessels on colour doppler imaging.

2021 ◽  
Vol 70 (4) ◽  
pp. 243-245
Author(s):  
Jozef Šulhin ◽  
Jakub Mičaník ◽  
Jakub Lubojacký ◽  
Adam Kopecký ◽  
Petr Matoušek ◽  
...  

Mucocele of the paranasal sinuses are benign cystic lesions filled with mucus. They occur in the sphenoid sinus in 1–2% of all paranasal sinuses, most often in the fourth decade of life. Clinical manifestations are non-specific, caused by pressure expansion into anatomical structures immediately adjacent to the sphenoid sinus. They are manifested by headaches, dropped eyelids, impaired movement of the globe, and impaired vision. In the differential dia­gnosis, it is necessary to distinguish them from tumour processes and processes propagating from the intracranium. Computed tomography (CT) and Magnetic Resonance Imaging (MRI) play an important role in the dia­gnosis, the definitive dia­gnosis is determined by perioperative findings and histological examination. Curative surgical options include endoscopic transnasal sphenoidotomy with marsupialization. In this article, we present a case of a patient with a mucocele of the sphenoid sinus, which was the cause of unilateral blindness. Keywords: marsupialization – mucocele – sphenoid sinus – endoscopic transnasal sphenoidotomy


2014 ◽  
Vol 4 ◽  
pp. 23 ◽  
Author(s):  
Seema Narang ◽  
Supreethi Kohli ◽  
Vinod Kumar ◽  
Raj Chandoke

Aggressive angiomyxoma is a rare mesenchymal tumor involving the pelvic-perineal region. It occurs during the third and fourth decade of life and is predominantly seen in females. It presents clinically as a soft tissue mass in variable locations such as vulva, perianal region, buttock, or pelvis. Assessment of extent of the tumor by radiological evaluation is crucial for surgical planning; however, biopsy is essential to establish diagnosis. We present the radiological and pathological features seen in a 43-year-old female diagnosed with abdominal angiomyxoma with an unusual extension to the perineum.


2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Wei-Xia Peng ◽  
Ryuichi Wada ◽  
Shoko Kure ◽  
Masaharu Fukunaga ◽  
Zenya Naito

Background: Superficial myofibroblastoma (SMF) is a very rare benign mesenchymal tumor in the female lower genital tract. Only 46 cases have been reported in the English language literature, among which only 7 cases arose in the vulva. Sometimes SMF histologically mimics aggressive angiomyxoma (AA) in which massive myxoid change in stroma is characteristic. We herein report a case of vulvar SMF with prominent myxoid stroma and review the literature with the emphasis on the differential diagnosis of SMF and AA. Case presentation: a 37-year-old woman presented with a painless mass in the vulva. Magnetic resonance imaging (MRI) showed a well-circumscribed 7 cm mass in the subcutis of the vulva. The tumor was resected. Histopathologically, the tumor was characterized by sparsely populated spindle-shaped cells in the fibromyxoid stroma. Thin-walled blood vessels were detected. Mitoses or pleomorphism was not found. Tumor cells were positive for vimentin, ER, PgR, and desmin. Some cells were positive for alpha-SMA and CD34. All cells were negative for S100 protein. Conclusions: because SMF and AA show different clinical prognoses, distinguishing SMF from AA is important. However, SMF may share many common histological features with AA: superficial localization (above fascia), sharp borderline from adjacent tissue, expansive growth pattern; a specific vascular pattern will lead to an accurate diagnosis of SMF. Familiarization with the histological characteristics of the two entities will help to make a prognostic prediction.


2019 ◽  
Vol 05 (02) ◽  
pp. 078-081
Author(s):  
Sumit Pandita ◽  
Irfan Bashir ◽  
Manish Sharma ◽  
Swarnita Sahu

AbstractAngiomyxomas are soft tissue tumors that are exceedingly rare with very few cases described in literature. They are classified into a less aggressive superficial variant and a deeper aggressive variant commonly called aggressive angiomyxomas (AA). The cross-sectional imaging, particularly magnetic resonance imaging (MRI), plays an essential role in the diagnosis and management of AA. We report a rare case of Aggressive angiomyxoma in a 28-year-old female.


2012 ◽  
Vol 25 (2) ◽  
pp. 200-205 ◽  
Author(s):  
K. Gangadhar ◽  
D. Santhosh

Disseminated cysticercosis is a rare form of cysticercosis in which the cysticerci spread throughout the body. We describe the case of a seven-year-old child with disseminated cysticercosis. He presented with a one month history of swelling of the whole body, unable to walk for one month and swelling of both eyes for 20 days. After extensive investigation from superficial musculoskeletal ultrasound B-scan of eye, brain computed tomography, brain magnetic resonance imaging (MRI), whole body MRI and pathologic biopsy, the child was diagnosed as having cysticercosis involving the brain, retina and skeletal muscles throughout the whole body.


2021 ◽  
Vol 16 (2) ◽  
pp. 168-173
Author(s):  
Mihai Leonard C. GRECESCU ◽  
◽  

The diagnosis of Graves’ ophtalmopathy (GO) is based on clinical examination, laboratory tests (indicating thyroid dysfunction and inflammatory and autoimmune unbalance) and imaging studies (such computed tomography, magnetic resonance imaging, ultrasound and colour Doppler imaging). Imaging studies can be helpful in establishing the certain diagnosis of GO, because they provide objective morphological findings of the orbital structures. An important role of imaging studies is revealed in differential diagnosis versus other orbital diseases and can be also used to evaluate the progression of the disease and follow-up after clinical or surgical treatment.


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