scholarly journals Association of haematological and biochemical parameters, ultrasonographic and upper GI endoscopic findings with sero prevalence of HBV and HCV among chronic liver disease patients in a tertiary care hospital

2020 ◽  
Vol 1 (5) ◽  
pp. 52-61
Author(s):  
Richmond Ronald Gomes ◽  
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Biochemical Parameters ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Liver ◽  
Care Hospital ◽  
Endoscopic Findings ◽  
Upper Gi

Hematological, Biochemical and Etiological factors of Chronic Liver Disease in a tertiary care Hospital of Lahore

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Sami Ullah Mumtaz ◽  
Amna Akbar ◽  
Humaira Waseem ◽  
Tayyeba Komal ◽  
Somia Iqtadar ◽  
...  
Keyword(s):  
Liver Disease ◽  
Hepatic Encephalopathy ◽  
Hepatitis C ◽  
Chronic Liver Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Liver ◽  
Care Hospital ◽  
Alcoholic Fatty Liver ◽  
Etiological Factors

Chronic Liver Disease (CLD) progresses from hepatocyte inammation to brosis, regeneration, cirrhosis and in some cases to Hepatocellular Carcinoma (HCC). In general, the main etiologies of Liver Cirrhosis (LC) are viral infections (hepatitis C and B viruses), chronic alcohol abuse and Non-Alcoholic Fatty Liver Disease (NAFLD), including Non-Alcoholic Steato Hepatitis (NASH). Major complications of CLD are ascites, upper gastrointestinal bleeding, jaundice (acute or chronic) and hepatic encephalopathy. Abstract:Study Design: Cross-sectional.Conclusions: This study assesses the etiological factors and complications of CLD in a tertiary care hospital of Lahore, Pakistan. Objectives: Methods: Study was carried out in indoor and Accident & Emergency Departments of Mayo Hospital Lahore. 100 clinically diagnosed CLD cases were chosen through “Convenient Sampling” technique during 3 months. Observations: Most common complications of CLD were upper GI variceal Bleeding (48%) & hepatic encephalopathy (34%) and acute or chronic hepatitis (AVH) (33%). Other less common complications observed were hepatorenal syndrome (10%), Spontaneous bacterial peritonitis (15%), Ascites (5%) and HCC (10%). Hepatitis C was found as main etiological factor of CLD. Bleeding and hepatic encephalopathy are the common complications. Awareness programmes regarding CLD and its complications are mandatory in our society to improve human health.

scholarly journals Upper Gi Endoscopy-indications and Findings at Tertiary Care Hospital Hyderabad/Jamshoro

2021 ◽  
pp. 46-50
Author(s):  
Jalpa Devi ◽  
Muhammad Akram Bajwa ◽  
Nasrullah Aamer ◽  
Rabia Farooque ◽  
Hira Laghari ◽  
...  
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Esophageal Varices ◽  
Chronic Liver ◽  
Care Hospital ◽  
Gi Endoscopy ◽  
Endoscopic Findings ◽  
Upper Gi ◽  
Upper Gi Endoscopy ◽  
Gi Bleed

Objective: To document different indications and findings of upper GI Endoscopy in our endoscopy suite. Methods: A descriptive study of 500 patients who underwent upper gastrointestinal (UGI) endoscopy was conducted in the Endoscopy Unit of PNS DRIGH LUMHS Jamshoro and Civil Hospital Hyderabad from April to September 2020. Included patients underwent UGI endoscopy. Demographic data including indications and endoscopic findings of the patients was collected via study proforma. Results: Total five hundred patients were studied; their mean age was 42.4±16.8 years. Out of all 52.8% were males. Upper GI bleed was the commonest indication (33.2%) followed by dysphagia (21.6%), epigastrium pain (10%), surveillance and screening of varices (9% and 8.2% respectively).  The most common endoscopic findings were esophageal varices (32.2 %), gastritis (18.8%), and normal (11.4%). In patients with esophageal varices, 77.4% had chronic liver disease with positive serology for HCV and HBV in 63.4% and 23% respectively. Conclusion: The most common indication was upper GI bleed with esophageal varices for upper GI endoscopy. The underlying etiology of varices reflects the high burden of chronic liver disease due to viral hepatitis.

scholarly journals Severity of thrombocytopenia with different grades of esophageal varices in chronic liver disease patients undergoing gastroscopy’s in a Tertiary Care Hospital.

2019 ◽  
Vol 26 (10) ◽  
pp. 1742-1747
Author(s):  
Raj Kumar Lohana ◽  
Riaz Hussain Awan ◽  
Seema Nayab ◽  
Khadim Hussain Awan ◽  
Faqir Muhammad Awan
Keyword(s):  
Platelet Count ◽  
Liver Disease ◽  
Chronic Liver Disease ◽  
Esophageal Varices ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Liver ◽  
High Yield ◽  
Care Hospital ◽  
The Mean

Objectives: To correlate severity of thrombocytopenia with different grades of esophageal varices in chronic liver disease patients undergoing EGD in a tertiary care hospital. Study Design: Cross sectional study. Setting: Gastroenterology & Hepatology Department at Liaquat National. Period: Six months from Jan to June 2016. Material and Methods: Seventy six subjects of chronic liver disease were recruited and studied for correlation between platelet count and esophageal varices by gastroscopy while the data was analyzed in SPSS version 17. Period: From July 2016 to Dec 2016. Results: There were 55 (72.4%) males and 21 (27.6%) females. The mean age was 45.6 ± 14.7 years. 10 (13.2%) had Hepatitis B, 58 (76.3%) Hepatitis C, 01 (1.3%) Wilson’s disease, 03 (3.9%) Autoimmune disease and 04 (5.3%) Alcoholic liver disease. 09 (11.8%) had Child-Pugh Class A, 41 (53.9%) Class B and 26 (34.2%) had Class C. The mean platelet count was 85/µl ± 40.2/µl. Out of 76 patients 70 (92.1%) had esophageal varices. 23 (30.3%) had grade III varices, 19 (25%) had grade II, 14 (18.4%) each had grade I & IV and 06 (7.9%) had grade 0 varices. Conclusion: thrombocytopenia can predict the occurrence of esophageal varices in cirrhotic population while gastroscopy has high yield for varices.

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