BLOOD FLOW IN CORONARY ARTERY BIFURCATION CALCULATED BY TURBULENT FINITE ELEMENT MODEL

2021 ◽  
Author(s):  
Aleksandar Nikolić ◽  
◽  
Marko Topalović ◽  
Milan Blagojević ◽  
Vladimir Simić
Keyword(s):  
Finite Element ◽  
Blood Flow ◽  
Kinetic Energy ◽  
Finite Element Model ◽  
Fluid Velocity ◽  
Fluid Pressure ◽  
Element Model ◽  
Viscous Sublayer ◽  
Flow Problems ◽  
Analysis Of Results

Simulation of blood flow in this paper is analyzed using two-equation turbulent finite element model that can calculate values in the viscous sublayer. Implicit integration of the equations is used for determining the fluid velocity, fluid pressure, turbulence, kinetic energy, and dissipation of turbulent kinetic energy. These values are calculated in the finite element nodes for each step of incremental- iterative procedure. Developed turbulent finite element model, with the customized generation of finite element meshes, is used for calculating complex blood flow problems. Analysis of results showed that a cardiologist can use proposed tools and methods for investigating the hemodynamic conditions inside bifurcation of arteries.

scholarly journals Development and analytical validation of a finite element model of fluid transport through osteochondral tissue

2020 ◽  
Author(s):  
Brady D. Hislop ◽  
Chelsea M. Heveran ◽  
Ronald K. June
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Fluid Transport ◽  
Fluid Pressure ◽  
Viscoelastic Model ◽  
Element Model ◽  
Pressure Gradients ◽  
Superficial Zone ◽  
Bone Interface ◽  
Osteochondral Tissue

AbstractFluid transport between cartilage and bone is critical to joint health. The objective of this study was to develop and analytically validate a finite element model of osteochondral tissue capable of modeling cartilage-bone fluid transport. A biphasic viscoelastic model using an ellipsoidal fiber distribution was created with three distinct layers of cartilage (superficial zone, middle zone, and deep zone) along with a layer of subchondral bone. For stress-relaxation in unconfined compression, our results for compressive stress, radial stress, effective fluid pressure, and elastic recoil were compared with established biphasic analytical solutions. Our model also shows the development of fluid pressure gradients at the cartilage-bone interface during loading. Fluid pressure gradients developed at the cartilage-bone interface with consistently higher pressures in cartilage following initial loading to 10% strain, followed by convergence towards equal pressures in cartilage and bone during the 400s relaxation period. These results provide additional evidence that fluid is transported between cartilage and bone during loading and improves upon estimates of the magnitude of this effect through incorporating a realistic distribution and estimate of the collagen ultrastructure. Understanding fluid transport between cartilage and bone may be key to new insights about the mechanical and biological environment of both tissues in health and disease.

Description and Validation of a Finite Element Model of Backflow During Infusion Into a Brain Tissue Phantom

2012 ◽  
Vol 8 (1) ◽  
Author(s):  
José J. García ◽  
Ana Belly Molano ◽  
Joshua H. Smith
Keyword(s):  
Finite Element ◽  
Hydraulic Conductivity ◽  
Finite Element Model ◽  
Brain Tissue ◽  
Nonlinear Boundary ◽  
Fluid Pressure ◽  
Element Model ◽  
Analytical Models ◽  
External Boundary ◽  
Forward Flow

An axisymmetric biphasic finite element model is proposed to simulate the backflow that develops around the external boundary of the catheter during flow-controlled infusions. The model includes both material and geometric nonlinearities and special treatments for the nonlinear boundary conditions used to represent the forward flow from the catheter tip and the axial backflow that occurs in the annular gap that develops as the porous medium detaches from the catheter. Specifically, a layer of elements with high hydraulic conductivity and low Young’s modulus was used to represent the nonlinear boundary condition for the forward flow, and another layer of elements with axial hydraulic conductivity consistent with Poiseuille flow was used to represent the backflow. Validation of the model was performed by modifying the elastic properties of the latter layer to fit published experimental values for the backflow length and maximum fluid pressure obtained during infusions into agarose gels undertaken with a 0.98-mm-radius catheter. Next, the finite element model predictions showed good agreement with independent experimental data obtained for 0.5-mm-radius and 0.33-mm-radius catheters. Compared to analytical models developed by others, this finite element model predicts a smaller backflow length, a larger fluid pressure, and a substantially larger percentage of forward flow. This latter difference can be explained by the important axial flow in the tissue that is not considered in the analytical models. These results may provide valuable guidelines to optimize protocols during future clinical studies. The model can be extended to describe infusions in brain tissue and in patient-specific geometries.

A 3D Biphasic Finite Element Model of the Human Knee Joint for the Study of Tibiofemoral Contact and Fluid Pressurization

2013 ◽  
Author(s):  
Hongqiang Guo ◽  
Suzanne A. Maher ◽  
Robert L. Spilker
Keyword(s):  
Finite Element ◽  
Fluid Flow ◽  
Knee Joint ◽  
Contact Problem ◽  
Finite Element Model ◽  
Soft Tissues ◽  
Fluid Pressure ◽  
Element Model ◽  
Human Knee Joint ◽  
Biphasic Finite Element

Biphasic theory which considers soft tissue, such as articular cartilage and meniscus, as a combination of a solid and a fluid phase has been widely used to model their biomechanical behavior [1]. Though fluid flow plays an important role in the load-carrying ability of soft tissues, most finite element models of the knee joint consider cartilage and the meniscus as solid. This simplification is due to the fact that biphasic contact is complicated to model. Beside the continuity conditions for displacement and traction that a single-phase contact problem consists of, there are two additional continuity conditions in the biphasic contact problem for relative fluid flow and fluid pressure [2]. The problem becomes even more complex when a joint is being modeled. The knee joint, for example, has multiple contact pairs which make the biphasic finite element model of this joint far more complex. Several biphasic models of the knee have been developed [3–9], yet simplifications were included in these models: (1) the 3D geometry of the knee was represented by a 2D axisymmetric geometry [3, 5, 6, 9]; (2) no fluid flow was allowed between contact surfaces of the soft tissues [4, 8] which is inconsistent with the equation of mass conservation across the contact interface [10]; (3) zero fluid pressure boundary conditions were inaccurately applied around the contact area [7].

scholarly journals A Computational Simulation of the Effect of Hemodilution on Oxygen Transport in Middle Cerebral Artery Vasospasm

2011 ◽  
Vol 31 (11) ◽  
pp. 2209-2217 ◽  
Author(s):  
Prashant Chittiboina ◽  
Bharat Guthikonda ◽  
Christian Wollblad ◽  
Steven A Conrad
Keyword(s):  
Finite Element ◽  
Blood Flow ◽  
Finite Element Model ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Oxygen Transport ◽  
Stokes Equations ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Computational Simulation ◽  
Element Model

Cerebral vasospasm after aneurysmal subarachnoid hemorrhage is a potentially severe sequel. The induction of hypertension, hypervolemia, and hemodilution is advocated for vasospasm, but it is unclear whether hemodilution confers any benefit. A finite element model of oxygen transport in the proximal middle cerebral artery (MCA) was used to evaluate the complex relationship among hematocrit, viscosity, oxygen content, and blood flow in the setting of vasospasm. A single-phase non-Newtonian finite element model based on three-dimensional incompressible Navier–Stokes equations was constructed of the M1 segment. The model was solved at vessel stenoses ranging from 0% to 90% and hematocrit from 0.2 to 0.6. A small area of poststenotic recirculation was seen with mild (30%) stenosis. Poststenotic eddy formation was noted with more severe (60% to 90%) stenosis. Volumetric flow was inversely related to hematocrit at mild stenosis (0% to 30%). With near-complete stenosis (90%), a paradoxical increase in flow was seen with increasing hematocrit. Oxygen transport across the segment was related to hematocrit at all levels of stenosis with increasing oxygen transport despite a reduction in blood flow, suggesting that with clinically significant vasospasm in the MCA, hemodilution does not improve oxygen transport, but to the contrary, that ischemia may be worsened.

scholarly journals Computational Investigation on the Biomechanical Responses of the Osteocytes to the Compressive Stimulus: A Poroelastic Model

2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Liping Wang ◽  
Jianghui Dong ◽  
Cory J. Xian
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Pore Pressure ◽  
Bone Cells ◽  
Fluid Velocity ◽  
Bone Matrix ◽  
Element Model ◽  
Major Type ◽  
Biomechanical Responses ◽  
Osteocyte Lacunar

Osteocytes, the major type of bone cells embedded in the bone matrix and surrounded by the lacunar and canalicular system, can serve as biomechanosensors and biomechanotranducers of the bone. Theoretical analytical methods have been employed to investigate the biomechanical responses of osteocytes in vivo; the poroelastic properties have not been taken into consideration in the three-dimensional (3D) finite element model. In this study, a 3D poroelastic idealized finite element model was developed and was used to predict biomechanical behaviours (maximal principal strain, pore pressure, and fluid velocity) of the osteocyte-lacunar-canalicular system under 150-, 1000-, 3000-, and 5000-microstrain compressive loads, respectively, representing disuse, physiological, overuse, and pathological overload loading stimuli. The highest local strain, pore pressure, and fluid velocity were found to be highest at the proximal region of cell processes. These data suggest that the strain, pore pressure, and fluid velocity of the osteocyte-lacunar-canalicular system increase with the global loading and that the poroelastic material property affects the biomechanical responses to the compressive stimulus. This new model can be used to predict the mechanobiological behaviours of osteocytes under the four different compressive loadings and may provide an insight into the mechanisms of mechanosensation and mechanotransduction of the bone.

Analysis on Oil Extraction Progressing Cavity Pump Three-Dimensional Finite Element Model

2014 ◽  
Vol 644-650 ◽  
pp. 670-673
Author(s):  
Guo You Han ◽  
Ming Qi Wang ◽  
Yu Hou ◽  
Qiang Li
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Finite Element Model ◽  
Fluid Pressure ◽  
Three Dimensional ◽  
Element Model ◽  
Uniaxial Tensile ◽  
Uniaxial Tensile Test ◽  
Analysis Model ◽  
Element Analysis

The finite element analysis of PCP involves three nonlinear of geometry, material and contact, and the load of PCP is diversity, leading to it difficult to establish the finite element model and calculate by finite method. This article takes GLB120-27 as an example, to establish 3D solid model of PCP by using SolidWorks; to determine M-R model constant of stator rubber by using the data of uniaxial tensile test: to separate the seal band from the stator chamber by using Boolean operation and set up contact pairs, to achieve the correct simulation of stator chamber fluid pressure; to correctly simulate the interference fit between stator and rotor through setting correlation parameters; to establish 3D finite element analysis model and verify the correctness by using the experiment data of hydraulic characteristics of PCP.

Sign in / Sign up

Export Citation Format

Share Document