WuXi STA plans pharmaceutical chemical facility in Delaware

2021 ◽  
pp. 13-13
Author(s):  
Rick Mullin
Keyword(s):  
Pharmaceutical Chemical

scholarly journals Enhancing Pervaporation Membrane Selectivity by Incorporating Star Macromolecules Modified with Ionic Liquid for Intensification of Lactic Acid Dehydration

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1811
Author(s):  
Valeriia Rostovtseva ◽  
Alexandra Pulyalina ◽  
Roman Dubovenko ◽  
Ilya Faykov ◽  
Kseniya Subbotina ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Lactic Acid ◽  
Polymer Matrix ◽  
Separation Factor ◽  
Membrane Structure ◽  
High Performance ◽  
Separation Efficiency ◽  
Pharmaceutical Chemical ◽  
Permeate Flux ◽  
Membrane Components

Modification of polymer matrix by hybrid fillers is a promising way to produce membranes with excellent separation efficiency due to variations in membrane structure. High-performance membranes for the pervaporation dehydration were produced by modifying poly(2,6-dimethyl-1,4-phenylene oxide) (PPO) to facilitate lactic acid purification. Ionic liquid (IL), heteroarm star macromolecules (HSM), and their combination (IL:HSM) were employed as additives to the polymer matrix. The composition and structure of hybrid membranes were characterized by X-ray diffraction and FTIR spectroscopy. Scanning electron microscopy was used to investigate the membranes surface and cross-section morphology. It was established that the inclusion of modifiers in the polymer matrix leads to the change of membrane structure. The influence of IL:HSM was also studied via sorption experiments and pervaporation of water‒lactic acid mixtures. Lactic acid is an essential compound in many industries, including food, pharmaceutical, chemical, while the recovering and purifying account for approximately 50% of its production cost. It was found that the membranes selectively remove water from the feed. Quantum mechanical calculations determine the favorable interactions between various membrane components and the liquid mixture. With IL:HSM addition, the separation factor and performance in lactic acid dehydration were improved compared with pure polymer membrane. The best performance was found for (HSM: IL)-PPO/UPM composite membrane, where the permeate flux and the separation factor of about 0.06 kg m−2 h−1 and 749, respectively, were obtained. The research results demonstrated that ionic liquids in combination with star macromolecules for membrane modification could be a promising approach for membrane design.

Believe they can succeed, and they will: intrapreneurial behavior and leadership

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Muhammad Farrukh ◽  
Fanchen Meng ◽  
Ali Raza
Keyword(s):  
Organizational Climate ◽  
Structural Equation ◽  
Chemical Engineering ◽  
Theoretical Development ◽  
Equation Modeling ◽  
Pharmaceutical Chemical ◽  
Participative Leadership ◽  
Content Type ◽  
Member Exchange

PurposeA leader's job is not to put greatness into people, but rather to recognize that it already exists and to create an environment where that greatness can emerge and grow (Smith, 2014). Based on Brad Smith's quote, the purpose of this study is to investigate the role of the leader's expectations, leader-member exchange (LMX) and organizational climate for innovation in fostering the intrapreneurial behavior (IB) of employees.Design/methodology/approachData were collected from employees and their supervisors working across industries such as pharmaceutical, chemical, engineering and manufacturing. Collected data were then analyzed using the structural equation modeling technique.FindingsThe authors’ results show that LMX and leaders' expectations are positively linked to employees' IB. Moreover, this association is mediated by organizational climate.Practical implicationsThis study's findings contribute to the literature on intrapreneurship and may also help practitioners formulate interventions to foster IB in organizations that will ultimately lead to higher performance.Originality/valueThis study attempted to investigate the effect of LMX and the Pygmalion effect on IB through employees' perception of organizational climate for innovation. The literature in this field is scarce and theoretical development is weak because traditional collaborative or participative leadership approaches are more relevant to an outcome than innovation.

scholarly journals Study on the effect of electrocatalytic oxidation treatment of 2,4,6-Trinitrophenol wastewater

2018 ◽  
Vol 238 ◽  
pp. 03003
Author(s):  
Yaling Li ◽  
Wenqiang Jiang ◽  
Ruyu Li
Keyword(s):  
Current Density ◽  
Electrocatalytic Oxidation ◽  
Electrolyte Concentration ◽  
Removal Rate ◽  
Pharmaceutical Chemical ◽  
Oxidation Treatment ◽  
Titanium Electrode ◽  
First Order Kinetics ◽  
Oxidation Technology ◽  
Aromatic Nitro

2,4,6-Trinitrophenol is a toxic aromatic nitro-compounds that widely used in pharmaceutical, chemical and pesticide production. Due to its stable structure and poor biodegradability, advanced electrocatalytic oxidation technology was selected to treat simulated wastewater. The goal of the present work is to optimize the electrolysis conditions such as current density, electrolysis pH, and electrolyte concentration. A Pt modified TiO2 electrode was chosen as the anode accompanied with a titanium electrode of the same size as the cathode The results showed that the removal efficiency of 2,4,6-Trinitrophenol was the highest when the current density was 20mA/cm2, electrolyte pH=5, electrolyte concentration was 2 g/L. Under the optimal condition, the removal rate of 2,4,6-Trinitrophenol reached 99.76% after 120 minutes electrolysis. The decay of TNP could also be described by the pseudo-first-order kinetics formula with respect to TNP concentration. Therefore, electrocatalytic oxidation technology might provide an effective method for the degradation of nitroaromatic organic compounds.

scholarly journals Consciousness Energy Healing Treatment: Spectroscopic and Calorimetric Evaluation of the Biofield Energy Treated Hydroxypropyl β-Cyclodextrin

2019 ◽  
Vol 2 (2) ◽  
pp. 14-24
Author(s):  
Dahryn Trivedi ◽  
Mahendra Kumar Trivedi ◽  
Alice Branton ◽  
Gopal Nayak ◽  
Snehasis Jana
Keyword(s):  
Weight Loss ◽  
Latent Heat ◽  
Control Sample ◽  
Raw Material ◽  
Heat Of Fusion ◽  
Drug Preparation ◽  
Pharmaceutical Chemical ◽  
Treated Sample ◽  
New Form ◽  
Energy Healing

Hydroxypropyl β-Cyclodextrin (HPBCD) used in food, pharmaceutical, chemical industries, as well as environmental, and agriculture engineering. But the major issue related to HPBCD is the low solubility profile. In this study, the influence of the Consciousness Energy Healing Treatment (the Trivedi Effect®) on the physicochemical properties of HPBCD was evaluated using spectroscopic and calorimetric analytical techniques. The test sample (HPBCD) was divided into control sample and treated sample. The control sample did not receive the Biofield Energy Treatment. Whereas, the treated sample received the Biofield Energy Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi. The particle size values of the treated sample were decreased by 3.28%(d10), 1.36%(d50), 0.45%(d90), and 1.04%{D(4,3)}; therefore, the specific surface area was increased by 1.9% compared with the control sample. The evaporation temperature of the treated HPBCD sample was significantly decreased by 19.89%; however, the latent heat of evaporation and latent heat of fusion were significantly increased by 56.27% and 47.41%, respectively compared with the control sample.The total weight loss in the treated HPBCD was decreased by 5.11%; whereas, the residue amount was significantly 309.67% more compared to the control sample.The results indicated that the Trivedi Effect® might have produced a new form of HPBCD which may show better thermal stability, solubility, dissolution rate, and bioavailability. This new form of HPBCD would be more useful for improvement of solubility of the lipophilic drug, preparation of cholesterol free food products, weight loss supplements, anti-obesity medication, stabilize volatile and unstable compounds, and other manufacturing industry using it as a raw material.

Study of external factors to minimize segregation of granular particles

2020 ◽  
Vol 31 (10) ◽  
pp. 2050147
Author(s):  
Saleema Panda ◽  
Danielle S Tan
Keyword(s):  
Food Processing ◽  
External Factors ◽  
Small Scale ◽  
Pharmaceutical Chemical ◽  
Wall Roughness ◽  
Related Factors ◽  
End Products ◽  
Granular Particles ◽  
Scale Experiment

Segregation of granular particles affects the quality of end products in the pharmaceutical, chemical and food processing industries. Many researchers have worked on controlling the mechanical properties of granular particles to minimize segregation. In this paper, we studied different chute-related factors — inclination angle, friction, fill, channel geometry and base profile — and their effects on segregation. We conducted a small-scale experiment with chute inclined at different angles, and also numerical simulations performed using an open-source discrete element method (DEM) code — LIGGGHTS. We found the optimal condition for minimum segregation of a binary granular mixture. We concluded that segregation is minimized if the stream-wise velocity is low, for example, by keeping the chute at a low inclination [Formula: see text] and increasing the wall roughness to 0.14.

Near-Infrared Spectrophotometry: A New Dimension in Clinical Chemistry

1992 ◽  
Vol 38 (9) ◽  
pp. 1623-1631 ◽  
Author(s):  
J W Hall ◽  
A Pollard
Keyword(s):  
Near Infrared ◽  
Serum Proteins ◽  
Clinical Laboratory ◽  
Clinical Chemistry ◽  
Electronic Transitions ◽  
Chemical Information ◽  
Pharmaceutical Chemical ◽  
Laboratory Measurements ◽  
Nondestructive Technique ◽  
Combination Bands

Abstract The near-infrared (NIR) spectral region (700-2500 nm) is a fertile source of chemical information in the form of overtone and combination bands of the fundamental infrared absorptions and low-energy electronic transitions. This region was initially perceived as being too complex for interpretation and consequently was poorly utilized. Advances in chemometric techniques that can extract massive amounts of chemical information from the highly overlapped, complex spectra have led to extensive use of NIR spectrophotometry (NIRS) in the food, agriculture, pharmaceutical, chemical, and polymer industries. The application of NIRS in clinical laboratory measurements is still in its infancy. NIRS is a simple, quick, nondestructive technique capable of providing clinically relevant analyses of biological samples with precision and accuracy comparable with the method used to derive the NIRS models. Analyses can be performed with little or no sample preparation and no reagents. The success of NIRS in any particular case is determined by the complexity of the sample matrix, relative NIR absorptivities of the constituents, and the wavelengths and regression technique chosen. We describe the general approach to data acquisition, calibration, and analysis, using serum proteins, triglycerides, and glucose as examples.

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