scholarly journals Early surgical outcomes after total hip replacement in systemic lupus erythematosus patients

2020 ◽  
Vol 58 (4) ◽  
pp. 451-455
Author(s):  
V. V. Mukhanov ◽  
S. A. Makarov ◽  
M. A. Makarov ◽  
T. V. Popkova
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Pain Intensity ◽  
Total Hip Replacement ◽  
Lupus Erythematosus ◽  
Surgical Outcomes ◽  
Hip Replacement ◽  
Systemic Lupus ◽  
Total Hip ◽  
Hip Function ◽  
One Year

Objective. To analyze early surgical outcomes after total hip replacement in systemic lupus erythematosus (SLE) patients.Subjects and Methods. The study included 42 SLE patients with femoral head osteonecrosis (ON) undergoing 59 total hip replacement (THR) surgeries at the traumatology and orthopedics department of VA Nasonova Research Institute of Rheumatology during 1998-2013 yy. All patients were thoroughly evaluated at baseline and one year after surgery using the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K), damage index (DI) of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) to assess the degree of irreversible organ damage, Harris hip function scale, and VAS for pain intensity to assess early results of THR procedure.Results. Significant improvement of pain intensity was documented based on VAS assessments, as well as hip function improvement from 40,0±14,9 (13,8 – 82,7) to 80,8±12 (46,7-96,0) scores based on Harris scale, improvement of SLE activity based on SLEDAI-2K assessment: from 0 -20 scores (median 4[4;8]) at baseline to 0 – 43 scores (median 0[0;4]) at one year, and DI – from 0-12 (median 3[2;5]) to 0 -15 scores one year after THR procedure. Complications including dislocation of femoral component, peroneal nerve paralysis, periprosthetic fracture, venous thrombosis, and delayed wound healing were documented totally in 10,2% of patients. No post-surgery deaths occurred.Conclusion. The results obtained are indicative of better pain control and improved hip function following THR in SLE patients. 

scholarly journals Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation

2021 ◽  
Vol 15 (2) ◽  
pp. 69-76
Author(s):  
F. A. Cheldieva ◽  
I. G. Kushnareva ◽  
V. V. Babak ◽  
A. E. Khramov ◽  
T. M. Reshetnyak
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Total Hip Replacement ◽  
Lupus Erythematosus ◽  
Hip Replacement ◽  
Factor V Leiden ◽  
Clotting Factor ◽  
Homozygous Mutation ◽  
Factor V ◽  
Systemic Lupus ◽  
Total Hip

The article provides a description of the systemic lupus erythematosus patient with multiple avascular bone necrosis (ABN), homozygous mutation in clotting factor V (Leiden) gene, who successfully underwent the total hip replacement. The role of high doses of glucocorticoids and coagulation disorders, in particular the homozygous mutation in factor V (Leiden) gene, in the development of ABN is discussed.

scholarly journals Total Hip Replacement in a Systemic Lupus Erythematosus Patient

2020 ◽  
Vol 19 (2) ◽  
pp. 322-325
Author(s):  
Mohd Shaffid Md Shariff ◽  
Hanizah Ngadiron ◽  
Nornazirah Azizan ◽  
Firdaus Hayati ◽  
Affirul Chairil Ariffin
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Avascular Necrosis ◽  
Total Hip Replacement ◽  
Lupus Erythematosus ◽  
Hip Replacement ◽  
Medical Science ◽  
Clinical Findings ◽  
Systemic Lupus ◽  
Total Hip ◽  
Radiological Features

Patients with systemic lupus erythematosus (SLE) going for surgery have put challenges to the treating surgeon, anaesthetist and physician as the patients can present with various medical complications perioperatively. It can be associated with polyarticular involvement especially avascular necrosis of the head of femur. The patients may present young with severe clinical findings and abnormal radiological features. The surgery in young SLE patients revolves on the longevity of the prosthesis used.We report a case of a 26-year-old lady with SLE going for right total hip replacement for her avascular necrosis of right hip. Bangladesh Journal of Medical Science Vol.19(2) 2020 p.322-325

scholarly journals Profiles of Biomarkers of Excess Alcohol Consumption in Patients Undergoing Total Hip Replacement: Correlation with Function

2011 ◽  
Vol 11 ◽  
pp. 1804-1811 ◽  
Author(s):  
Paul J. Jenkins ◽  
Andrew D. Duckworth ◽  
Francis P. C. Robertson ◽  
Colin R. Howie ◽  
James S. Huntley
Keyword(s):  
Total Hip Replacement ◽  
Hip Replacement ◽  
Alcohol Misuse ◽  
Future Research ◽  
Total Hip ◽  
Increased Risk ◽  
Functional Scores ◽  
Hip Function ◽  
One Year ◽  
General Physical

Aims. Patients who misuse alcohol may be at increased risk of surgical complications and poorer function following hip replacement. Identification and intervention may lead to harm reduction and improve the outcomes of surgery. The aim of this study was to determine the prevalence of biomarker elevation in patients undergoing hip replacement and to investigate any correlation with functional scores and complications.Methods. We performed a retrospective study that examined the profile of biomarkers of alcohol misuse in 1049 patients undergoing hip replacement.Results. Gamma-glutamyltransferase was elevated in 150 (17.6%), and mean corpuscular volume was elevated in 23 (4%). At one year general physical health was poorer where there was elevation ofγGT, and the mental health and hip function was poorer with elevation of MCV. There were no differences in complications.Discussion. Raised biomarkers can alert clinicians to potential problems. They also provide an opportunity to perform further investigation and offer intervention. Future research should focus on the use in orthopaedic practice of validated screening questionnaires and more sensitive biomarkers of alcohol misuse.Conclusion. This study demonstrates a potential substantial proportion of unrecognised alcohol misuse that is associated with poorer functional scores in patients after total hip replacement.

scholarly journals Hip tuberculosis at stage IV: Outcomes and some conditions for total hip replacement

2021 ◽  
Author(s):  
Hoan Do Dang ◽  
Xuan Thanh Dao ◽  
Trang Nguyen Khac ◽  
Ngo Van Toan
Keyword(s):  
Logistic Regression ◽  
Total Hip Replacement ◽  
Surgical Outcomes ◽  
Hip Replacement ◽  
Stage Iv ◽  
Sinus Tract ◽  
Tuberculosis Infection ◽  
Harris Hip Score ◽  
Total Hip ◽  
Hip Function

Abstract Background : Total hip replacement during active hip tuberculosis has been a controversial issue for a long time. Some authors advocate hip replacement during the healed stage, while others believe it should be done in active hip tuberculosis. The purpose of this study was to describe the surgical outcomes, a suitable time and necessary conditions for the total hip replacement in active hip tuberculosis. Methods: We conducted a quasi-experimental study. The study enrolled 40 patients with 42 active tuberculosis hips at stage IV treated by total hip replacement strategy between October 2016 and December 2019 at the National Lung Hospital, Vietnam. The patients had been done total hip replacement by either one- or two-stage depending on hip abscesses to assess surgical outcomes and some factors associated with the logistic regression analysis model. The patients were then evaluated based on Harris hip score and sinus tract formation. Results: The average follow-up was 30 months (range, 14-50 months). Surgical outcomes showed that 37 cases (88.1%) had an excellent hip function and no abscess or sinus tract formation. Four cases (9.5%) had sinus tract formations, but the hip function was still in the excellent class by Harris hip-score (HHS). One case (2.4%) had a good hip function with a Harris hip score of 86 points, without sinus tract formation. The binary logistic regression models revealed that sinus tract formation was associated with preoperative tuberculosis infection syndrome but not associated with pulmonary tuberculosis, acetabular osteomyelitis, trans-trochanteric osteomyelitis, a history of diabetes, rheumatoid arthritis, or corticosteroid dependence. The average time from patients getting antituberculosis treatment to hip replacement was 4.6 weeks. Conclusion: Total hip replacement for active hip tuberculosis was a practical and promised treatment method (excellent result: 88.1% and good: 11.9%). The surgery should be considered to improve patients' conditions pre-operation in taking anti-tubercular drugs, eliminating all abscesses, diminishing tuberculosis infection syndrome, inflammatory response, and choosing a suitable time of getting tuberculosis treatment.

Libman-Sacks endocarditis in a Bangladeshi patient suffering from rhupus

2019 ◽  
Vol 49 (4) ◽  
pp. 309-311 ◽  
Author(s):  
Shahana Zaman ◽  
Muhammad Abdur Rahim ◽  
Lima Asrin Sayami ◽  
Shaila Nabi ◽  
AKM Monwarul Islam ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Cardiac Lesions ◽  
One Year ◽  
Echocardiographic Evidence

Libman-Sacks endocarditis (LSE) is one of the most characteristic cardiac lesions in systemic lupus erythematosus (SLE). Patients may remain asymptomatic, while symptomatic patients often suffer with systemic emboli. These commonly test positive for anti-phospholipid antibody (aPA). The association of LSE with an overlap of rheumatoid arthritis (RA) and lupus (also known as ‘rhupus’) is rare. We report such a patient, who had been diagnosed as having RA seven years before and had suffered an acute ischaemic stroke one year previously and had echocardiographic evidence of LSE found during routine evaluation. However, she tested negative for aPA.

Outcomes of Primary Total Hip Arthroplasty in Systemic Lupus Erythematosus With a Proximally-Coated Cementless Stem

2013 ◽  
Vol 28 (9) ◽  
pp. 1663-1666 ◽  
Author(s):  
Kimona Issa ◽  
Qais Naziri ◽  
Vijay J. Rasquinha ◽  
Tiffany Tatevossian ◽  
Bhaveen H. Kapadia ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Lupus Erythematosus ◽  
Cementless Stem ◽  
Systemic Lupus ◽  
Total Hip ◽  
Primary Total Hip Arthroplasty

scholarly journals Relationship between remission, disease activity and patient-reported outcome measures in patients with recent-onset systemic lupus erythematosus

Lupus ◽  
2020 ◽  
Vol 29 (6) ◽  
pp. 625-630
Author(s):  
Rebecca Heijke ◽  
Mathilda Björk ◽  
Martina Frodlund ◽  
Laura McDonald ◽  
Evo Alemao ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Pain Intensity ◽  
Lupus Erythematosus ◽  
Well Being ◽  
Patient Reported Outcome Measures ◽  
Patient Reported Outcome ◽  
Systemic Lupus ◽  
Recent Onset ◽  
Patient Reported

Objective Definitions of remission in systemic lupus erythematosus (SLE; DORIS (1A/1B/2A/2B)), disease activity assessments and patient-reported outcome measures (PROMs) are useful in shared decision making between patients with SLE and physicians. We used longitudinal registry data from well-characterized Swedish patients with recent-onset SLE to explore potential correlations between DORIS status or disease activity, and PROMs. Methods Patients from the Clinical Lupus Register in North-Eastern Gothia, Sweden, who fulfilled the 1982 American College of Rheumatology and/or the 2012 Systemic Lupus International Collaborating Clinics classification criteria without prior organ damage, were enrolled at diagnosis. Data on treatments, serology, remission status (DORIS), disease activity (SLE Disease Activity Index-2000 (SLEDAI-2K)) and PROMs (quality of life: EuroQoL-5 Dimensions (EQ-5D); pain intensity, fatigue and well-being: visual analog scale (VAS) 0–100 mm) were collected during rheumatology clinic visits at months 0 (diagnosis), 6, 12, 24, 36, 48 and 60. Correlations were assessed using Pearson correlation and/or beta regression coefficients. Results A total of 41 patients were enrolled (median age = 39 years, 80% female, 85% white). Achievement of DORIS 1A and 2A (neither of which includes serology) significantly correlated with all PROMs (EQ-5D: p ≤ 0.02; pain: p = 0.0001; fatigue: p = 0.0051; well-being: p < 0.0001). Disease activity measures were correlated with VAS pain intensity ( p < 0.03) and VAS well-being ( p < 0.04). Conclusions Our findings illustrate the importance of the interplay between remission, disease activity assessments and PROMs. PROMs may be a useful tool in clinical practice, being administered prior to patient visits to streamline clinical care.

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