scholarly journals Hypothesis on Glucose Production Communication Model between the Brain and Internal Organs via Investigating the PPG Values of Pan-fried Solid Egg Meal vs. Egg Drop Liquid Soup Meal

2020 ◽  
pp. 1-3
Author(s):  
Gerald C Hsu ◽  

After reviewing the research results for six months, from September 2019 through February 2020, the author identified a probable internal communication model between the nervous system and certain vital internal organs, specifically the stomach and liver regarding postprandial plasma glucose (PPG) production. The author used a continuous glucose monitor device to collect 50,000 glucose data during the past 665 days. He focused on studying the relationships among different food nutritional contents, cooking methods, food material’s physical phases, and different characteristics and variants from his glucose waveform patterns. In this study, he focused on the three major meal groups based on food nutritional ingredients, meal’s preparation, and cooking methods of eggs, squash, and cabbage to create soup-based (liquid) meal and pan-fried (solid) meal. The PPG waveforms from these three meal groups demonstrated that soup-based liquid food produced a much lower glucose value than the pan-fried solid food. Although both liquid and solid meals have similar identical nutritional ingredients, he questions why did this occur? His hypothesis is that his PPG differences are due to specific physical phase of his finished meal either “liquid” or “solid”, which is his ready-to-eat meal’s final physical “phase” that determines his PPG characteristics and waveforms. The author utilized his GH-Method: math-physical medicine (MPM) approach to explore a T2D patient’s glucose production situation from a scientific view of the brain and nervous system’s functionalities. If this specific approach and above interpretation are accurate, we can then “trick” our brain into producing a “lesser” amount of glucose after food intake without altering or sacrificing the needed food nutritional balance. As a result, T2D patients can simply change their cooking method in order to lower both of their peak PPG values and their average PPG levels.


After reviewing the research results for six months, from September 2019 through February 2020, the author identified a probable internal communication model between the nervous system and certain vital internal organs, specifically the stomach and liver regarding postprandial plasma glucose (PPG) production. The author used a continuous glucose monitor device to collect 50,000 glucose data during the past 665 days. He focused on studying the relationships among different food nutritional contents, cooking methods, food material’s physical phases, and different characteristics and variants from his glucose waveform patterns. In this study, he focused on the three major meal groups based on food nutritional ingredients, meal’s preparation, and cooking methods of eggs, squash, and cabbage to create soup-based (liquid) meal and pan-fried (solid) meal. The PPG waveforms from these three meal groups demonstrated that soup-based liquid food produced a much lower glucose value than the pan-fried solid food. Although both liquid and solid meals have similar identical nutritional ingredients, he questions why did this occur? His hypothesis is that his PPG differences are due to specific physical phase of his finished meal either “liquid” or “solid”, which is his ready-to-eat meal’s final physical “phase” that determines his PPG characteristics and waveforms. The author utilized his GH-Method: math-physical medicine (MPM) approach to explore a T2D patient’s glucose production situation from a scientific view of the brain and nervous system’s functionalities. If this specific approach and above interpretation are accurate, we can then “trick” our brain into producing a “lesser” amount of glucose after food intake without altering or sacrificing the needed food nutritional balance. As a result, T2D patients can simply change their cooking method in order to lower both of their peak PPG values and their average PPG levels.


In this paper, the author presents the results of his national segmentation pattern analysis of the sensor PPG data based on both high-carb and low-carb intake amounts. It also verified his earlier findings on the communication model between the brain and internal organs such as the stomach, liver, and pancreas.


2020 ◽  
pp. 1-5
Author(s):  
Gerald C Hsu ◽  

In this paper, the author described the progress on his two-year long special research project, from 5/5/2018 through 8/13/2020, to identify a neural communication model between the brain’s cerebral cortex and certain internal organs such as the stomach, liver, and pancreas. He used a continuous glucose monitor (CGM) sensor collected postprandial plasma glucose (PPG) data to investigate the glucose production amount at different timing and waveform differences between 95 liquid egg meals and 110 solid egg meals


2020 ◽  
Author(s):  
Gerald C. Hsu

In this paper, the author analyzed his 1,707 meals that are segregated into low-carb and high-carb meals. The purpose is to attempt the validation of his hypothesis on the relationship from the directive of the brain to the gastrointestinal functions and liver’s glucose production capability by using PPG value changes over a smaller time segment (each segment with 15 minutes). The author uses the math-physical approach rather than a biochemical one


2020 ◽  
Vol 2 (2) ◽  

In this paper, the author presents the results of two clinical cases of CGM Sensor PPG data to confirm his hypotheses regarding the possible communication model between the brain and stomach/ liver/pancreas as well as the comparison of the health state of the pancreatic beta cells.


2020 ◽  
Vol 3 (3) ◽  

This article address the author’s hypothesis on the neurocommunication model existing between the brain and liver regarding production and glucose secretion in the early morning. This is based on the observation of the difference between glucose at wake up moment in the morning for the fasting plasma glucose (FPG), and glucose at the first bite of breakfast for the glucose at 0-minute or “open glucose” of postprandial plasma glucose (PPG). All of the eight identified glucoses of breakfast PPG are higher than the eight glucoses at time of wake up by a difference of an average of 8 mg/dL. The value difference using Method B of CGM sensor glucoses during the COVID-19 period offers the most accurate picture and credible glucose difference of 8 mg/dL between his FPG at wake-up moment and PPG at the first bite of breakfast. The author believes that the brain senses when a person wakes up due to different kinds of stimuli from many sources, including eye, environment, and even internal organs, which will alert the body to be in “active” mode requiring “energy” through glucose. Even though the person has not eaten anything or is not actively moving, the brain issues a marching order to the liver to produce or release glucose for the body to use in the forthcoming day. This hypothesis can currently explain why his glucose of eating his breakfast is ~8 mg/dL higher than his FPG at wakeup.


2021 ◽  
Author(s):  
Heinz-Josef Schmitt

Enterovirus A71 (EV A71) (genus enterovirus, family pircornaviridae) causes benign vesicular lesions on skin (hand, foot and mouth disease, HFMD) and mucous membranes of the mouth (herpangina), and also severe to life-threatening infections of the brain, the heart, and other internal organs. Disease outbreaks in the Asia-Pacific region regularly involve thousands of children <5 years resulting in many deaths. Such outbreaks are caused by specific EV genotypes that vary by time and place. While there are various promising and innovative options for treatment in development, none are licensed to date. Immunoglobulins may be beneficial through virus neutralization and modulation of the inflammatory response by the host. In China, 3 different highly efficacious and safe vaccines are commercially available; however, none are licensed outside the country. Roughly half a dozen vaccines are in the development pipeline, with some using innovative approaches and trying to broaden strain coverage.


1998 ◽  
Vol 44 (1) ◽  
pp. 40-42
Author(s):  
I. P. Grigoriev

The author hypothesizes a probable causative role of alteration of ascorbic acid concentration in the brain in the development of mental disease in diabetics. In order to verify this hypothesis, ascorbic acid was measured in the brain cortex of rats 21 days after induction of streptozotocin diabetes or 1 h after intraperitoneal injection of glucose in a dose of 5 g/kg. Ascorbic acid level was increased both in diabetes (456+26 yg/g tissue versus 415+37 \vg/g in the control, p<0.01) and in acute hyperglycemia (475+54 \tg/g versus 406+65 \xg/g in the control, p<0.001). This confirmed that changed concentration of ascorbic acid in the brain can promote the development of a mental disease in diabetics. In the liver the concentration of ascorbic acid was decreased in streptozotocin diabetes (by 17%), p<0.001) and increased in acute hypoglycemia (by 24%, p<0.01). The findings permit us to hypothesize that hypoglycemia inhibits the production of ascorbic acid from the liver to the blood in rats and impedes the transport of ascorbic acid through the gut wall into the blood in humans.


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