scholarly journals Perbandingan Efektivitas Anestesi Spinal Menggunakan Bupivakain 0,5% Hiperbarik Dosis 7,5 Mg dengan 5 Mg pada Seksio Sesarea

2020 ◽  
Vol 3 (1) ◽  
pp. 1-8
Author(s):  
Muh. Zulkifli ◽  
Andi Salahuddin ◽  
Muh. Ramli Ahmad
Keyword(s):  
Clinical Trial ◽  
Caesarean Section ◽  
Spinal Anesthesia ◽  
T Test ◽  
Double Blind ◽  
Double Blind Clinical Trial

Latar Belakang: Teknik anestesi yang efektif adalah tujuan utama dari teknik anestesi spinal, yang bertujuan meminimalkan efek samping pada ibu dan bayi baru lahir. Tujuan: Membandingkan ketinggian blok, onset dan durasi, efek samping antara Bupivakain 0,5% Hiperbarik dosis 7,5 Mg + Fentanyl 25 Mcg dan dosis 5 Mg + Fentanyl 25 Mcg pada seksio sesarea.Metode: Penelitian ini menggunakan pendekatan uji klinis acak tersamar ganda (Randomized double blind clinical trial). Sampel terdiri atas 2 kelompok yakni LD (Kelompok yang mendapatkan anestesi spinal bupivakain 0,5% hiperbarik 5 mg + fentanil 25 μg ) dan CD (Kelompok yang mendapatkan anestesi spinal bupivakain 0,5% hiperbarik 7,5 mg + fentanil 25 μg) dengan jumlah sampel masing-masing 20 orang. Data dianalisis menggunakan uji statistik Independen Sample T Test dengan tingkat kemaknaan α=0.05. Hasil: Ada perbedaan onset blok motorik (p=0,004), durasi motorik (p=0,000), durasi blok sensoris (p=0,000) antara kelompok LD dan kelompok CD. Sedangkan durasi operasi (p= 0,769), selisih perubahan TD Sistole (p> 0,05), selisih perubahan TD Diatole (p> 0,05), selisih perubahan nadi (p> 0,05), selisih perubahan MAP (p> 0,05), efek samping mual/muntah (p> 0,05) dan rescue (p> 0,05) menunjukkan tidak ada perbedaan.Simpulan: Onset blok sensorik lebih lama, dan durasi blok sensoris dan motorik lebih singkat pada kelompok LD dibanding CD sehingga ada perbedaan efektifitas bupivakain antara kedua kelompok. Tidak perbedaan yang bermakna untuk efek samping dan perubahan hemodinamik pada kedua kelompok. The Effectiveness of Spinal Anesthesia Using Bupivacaine 0.5% Hyperbaric Dosage 7.5 Mg with 5 Mg in Caesarean Section Surgery Abstract Latar Belakang: Teknik anestesi yang efektif adalah tujuan utama dari teknik anestesi spinal, yang bertujuan meminimalkan efek samping pada ibu dan bayi baru lahir. Tujuan: Membandingkan ketinggian blok, onset dan durasi, efek samping antara Bupivakain 0,5% Hiperbarik dosis 7,5 Mg + Fentanyl 25 Mcg dan dosis 5 Mg + Fentanyl 25 Mcg pada seksio sesarea.Metode: Penelitian ini menggunakan pendekatan uji klinis acak tersamar ganda (Randomized double blind clinical trial). Sampel terdiri atas 2 kelompok yakni LD (Kelompok yang mendapatkan anestesi spinal bupivakain 0,5% hiperbarik 5 mg + fentanil 25 μg ) dan CD (Kelompok yang mendapatkan anestesi spinal bupivakain 0,5% hiperbarik 7,5 mg + fentanil 25 μg) dengan jumlah sampel masing-masing 20 orang. Data dianalisis menggunakan uji statistik Independen Sample T Test dengan tingkat kemaknaan α=0.05. Hasil: Ada perbedaan onset blok motorik (p=0,004), durasi motorik (p=0,000), durasi blok sensoris (p=0,000) antara kelompok LD dan kelompok CD. Sedangkan durasi operasi (p= 0,769), selisih perubahan TD Sistole (p> 0,05), selisih perubahan TD Diatole (p> 0,05), selisih perubahan nadi (p> 0,05), selisih perubahan MAP (p> 0,05), efek samping mual/muntah (p> 0,05) dan rescue (p> 0,05) menunjukkan tidak ada perbedaan.Simpulan: Onset blok sensorik lebih lama, dan durasi blok sensoris dan motorik lebih singkat pada kelompok LD dibanding CD sehingga ada perbedaan efektifitas bupivakain antara kedua kelompok. Tidak perbedaan yang bermakna untuk efek samping dan perubahan hemodinamik pada kedua kelompok.

scholarly journals A comparison of the effect of dexamethasone and pethidine for prevention of shivering after spinal anesthesia in caesarean section: randomization clinical trial

2018 ◽  
Vol 5 (9) ◽  
pp. 2646-2650 ◽  
Author(s):  
Hamideh Gholami ◽  
Yousef Moradi ◽  
Zaher Khazaei ◽  
Shahrzad Tehrani
Keyword(s):  
Clinical Trial ◽  
Caesarean Section ◽  
Spinal Anesthesia ◽  
Normal Saline ◽  
Saline Group ◽  
Elective Cesarean Section ◽  
Double Blind ◽  
Dexamethasone Group ◽  
Postanesthetic Shivering ◽  
Significant Difference

Background: Postanesthetic shivering is one of the most common complications and problems after operations. Medications and drugs can be used to prevent postanesthetic shivering. The aim of this study is to compare the effects of Dexamethasone and Pethidine in preventing postanesthetic shivering after spinal anesthesia in Iranian women undergoing caesarean section. Method: This double-blind randomized clinical trial was performed in 66 pregnant women who were referred to Ayatollah Moosavi Hospital in Zanjan, Iran for elective cesarean section, from December 2011 to November 2012. All participants who have ASA I-II were randomly classified into three groups: Dexamethasone receivers (Group A), Pethidine receivers (Group B), and Normal Saline receivers (Group C). Data were collected and analyzed using SPSS16 software. IRCT registration number of this study is IRCT201112198469N1. Conclusion: Although statistically there was no significant difference between the three groups of Dexamethasone, Pethidine and Normal Saline receivers regarding shivering reduction; clinical complication rate in Dexamethasone group was lower comparedto Pethidine and Normal Saline groups. Results: There was no significant difference between three groups regarding shivering reduction. There were 11 (72.5%) trembling cases in Normal Saline group, 6 cases (27.3%) in Dexamethasone group, and 12 cases (54.5%) in Pethidine group.

scholarly journals Effect of Neem containing Toothpaste on Plaque and Gingivitis—A Randomized Double Blind Clinical Trial

2015 ◽  
Vol 16 (11) ◽  
pp. 880-883 ◽  
Author(s):  
S Supreetha ◽  
KN Abhishek ◽  
S Nubesh Khan ◽  
KH Chaithanya ◽  
Nishad Abdul
Keyword(s):  
Clinical Trial ◽  
Oral Hygiene ◽  
Dental Students ◽  
T Test ◽  
Control Group ◽  
First Year ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
And Control

ABSTRACT Aim The present study was designed to assess the effect of toothpaste containing neem on plaque and gingivitis. Materials and methods Randomized, double blind clinical trial was designed. Thirty first year dental students volunteered to participate in the study. Neem containing tooth paste was used as an intervention. Clinical examination was carried out using Silness and Loe plaque index (PI) and Loe and Silness gingival index (GI). Independent t-test and paired t-test was used for the intergroup and the intragroup comparison. Results Out of 30 participants, 22 (73.3%) were females and eight (26.7%) were males. A statistically significant difference was found between the test and control group after intervention with respect to the PI and GI. Conclusion Neem containing toothpaste can be used as an adjunct for maintenance of oral hygiene. Clinical significance Regular brushing with neem toothpaste might act as an adjunct to maintenance of good oral hygiene, and thus improve oral health. How to cite this article Abhishek KN, Supreetha S, Sam G, Khan SN, Chaithanya KH, Abdul N. Effect of Neem containing Toothpaste on Plaque and Gingivitis—A Randomized Double Blind Clinical Trial. J Contemp Dent Pract 2015;16(11):880-883.

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