scholarly journals Comparison of Neural Network and Machine Learning Approaches in Prediction of Chronic Kidney Disease

2021 ◽  
Vol 10 (3) ◽  
Author(s):  
Shreya Nag ◽  
Nimitha Jammula

The diagnosis of a disease to determine a specific condition is crucial in caring for patients and furthering medical research. The timely and accurate diagnosis can have important implications for both patients and healthcare providers. An earlier diagnosis allows doctors to consider more methods of treatment, allowing them to have a greater flexibility of tailoring their decisions, and ultimately improving the patient’s health. Additionally, a timely detection allows patients to have a greater control over their health and their decisions, allowing them to plan ahead. As advancements in computer science and technology continue to improve, these two factors can play a major role in aiding healthcare providers with medical issues. The emergence of artificial intelligence and machine learning can aid in addressing the challenge of completing timely and accurate diagnosis. The goal of this research work is to design a system that utilizes machine learning and neural network techniques to diagnose chronic kidney disease with more than 90% accuracy based on a clinical data set, and to do a comparative study of the performance of the neural network versus supervised machine learning approaches. Based on the results, all the algorithms performed well in prediction of chronic kidney disease (CKD) with more that 90% accuracy. The neural network system provided the best performance (accuracy = 100%) in prediction of chronic kidney disease in comparison with the supervised Random Forest algorithm (accuracy = 99%) and the supervised Decision Tree algorithm (accuracy = 97%).

Author(s):  
Pooja Sharma ◽  
Saket J Swarndeep

According the 2010 global burden of disease study, Chronic Kidney Diseases (CKD) was ranked 18th in the list of causes of total no. of deaths worldwide. 10% of the population worldwide is affected by CKD. The prediction of CKD can become a boon for the population to predict the health. Various method and techniques are undergoing the research phase for developing the most accurate CKD prediction system. Using Machine Learning techniques is the most promising one in this area due to its computing function and Machine Learning rules. Existing Systems are working well in predicting the accurate result but still more attributes of data and complicity of health parameter make the root layer for the innovation of new approaches. This study focuses on a novel approach for improving the prediction of CKD. In recent time Neural network system has discovered its use in disease diagnoses, which is depended upon prediction from symptoms data set. Chronic kidney disease detection system using neural network is shown here. This system of neural network accepts disease-symptoms as input and it is trained according to various training algorithms. After neural network is trained using back propagation algorithms, this trained neural network system is used for detection of kidney disease in the human body.


2021 ◽  
Vol 44 (4) ◽  
pp. 1-12
Author(s):  
Ratchainant Thammasudjarit ◽  
Punnathorn Ingsathit ◽  
Sigit Ari Saputro ◽  
Atiporn Ingsathit ◽  
Ammarin Thakkinstian

Background: Chronic kidney disease (CKD) takes huge amounts of resources for treatments. Early detection of patients by risk prediction model should be useful in identifying risk patients and providing early treatments. Objective: To compare the performance of traditional logistic regression with machine learning (ML) in predicting the risk of CKD in Thai population. Methods: This study used Thai Screening and Early Evaluation of Kidney Disease (SEEK) data. Seventeen features were firstly considered in constructing prediction models using logistic regression and 4 MLs (Random Forest, Naïve Bayes, Decision Tree, and Neural Network). Data were split into train and test data with a ratio of 70:30. Performances of the model were assessed by estimating recall, C statistics, accuracy, F1, and precision. Results: Seven out of 17 features were included in the prediction models. A logistic regression model could well discriminate CKD from non-CKD patients with the C statistics of 0.79 and 0.78 in the train and test data. The Neural Network performed best among ML followed by a Random Forest, Naïve Bayes, and a Decision Tree with the corresponding C statistics of 0.82, 0.80, 0.78, and 0.77 in training data set. Performance of these corresponding models in testing data decreased about 5%, 3%, 1%, and 2% relative to the logistic model by 2%. Conclusions: Risk prediction model of CKD constructed by the logit equation may yield better discrimination and lower tendency to get overfitting relative to ML models including the Neural Network and Random Forest.  


2020 ◽  
Author(s):  
Ada Admin ◽  
Jialing Huang ◽  
Cornelia Huth ◽  
Marcela Covic ◽  
Martina Troll ◽  
...  

Early and precise identification of individuals with pre-diabetes and type 2 diabetes (T2D) at risk of progressing to chronic kidney disease (CKD) is essential to prevent complications of diabetes. Here, we identify and evaluate prospective metabolite biomarkers and the best set of predictors of CKD in the longitudinal, population-based Cooperative Health Research in the Region of Augsburg (KORA) cohort by targeted metabolomics and machine learning approaches. Out of 125 targeted metabolites, sphingomyelin (SM) C18:1 and phosphatidylcholine diacyl (PC aa) C38:0 were identified as candidate metabolite biomarkers of incident CKD specifically in hyperglycemic individuals followed during 6.5 years. Sets of predictors for incident CKD developed from 125 metabolites and 14 clinical variables showed highly stable performances in all three machine learning approaches and outperformed the currently established clinical algorithm for CKD. The two metabolites in combination with five clinical variables were identified as the best set of predictors and their predictive performance yielded a mean area value under the receiver operating characteristic curve of 0.857. The inclusion of metabolite variables in the clinical prediction of future CKD may thus improve the risk prediction in persons with pre- and T2D. The metabolite link with hyperglycemia-related early kidney dysfunction warrants further investigation.


Terminology ◽  
2022 ◽  
Author(s):  
Ayla Rigouts Terryn ◽  
Véronique Hoste ◽  
Els Lefever

Abstract As with many tasks in natural language processing, automatic term extraction (ATE) is increasingly approached as a machine learning problem. So far, most machine learning approaches to ATE broadly follow the traditional hybrid methodology, by first extracting a list of unique candidate terms, and classifying these candidates based on the predicted probability that they are valid terms. However, with the rise of neural networks and word embeddings, the next development in ATE might be towards sequential approaches, i.e., classifying each occurrence of each token within its original context. To test the validity of such approaches for ATE, two sequential methodologies were developed, evaluated, and compared: one feature-based conditional random fields classifier and one embedding-based recurrent neural network. An additional comparison was added with a machine learning interpretation of the traditional approach. All systems were trained and evaluated on identical data in multiple languages and domains to identify their respective strengths and weaknesses. The sequential methodologies were proven to be valid approaches to ATE, and the neural network even outperformed the more traditional approach. Interestingly, a combination of multiple approaches can outperform all of them separately, showing new ways to push the state-of-the-art in ATE.


Geophysics ◽  
2020 ◽  
Vol 85 (4) ◽  
pp. WA41-WA52 ◽  
Author(s):  
Dario Grana ◽  
Leonardo Azevedo ◽  
Mingliang Liu

Among the large variety of mathematical and computational methods for estimating reservoir properties such as facies and petrophysical variables from geophysical data, deep machine-learning algorithms have gained significant popularity for their ability to obtain accurate solutions for geophysical inverse problems in which the physical models are partially unknown. Solutions of classification and inversion problems are generally not unique, and uncertainty quantification studies are required to quantify the uncertainty in the model predictions and determine the precision of the results. Probabilistic methods, such as Monte Carlo approaches, provide a reliable approach for capturing the variability of the set of possible models that match the measured data. Here, we focused on the classification of facies from seismic data and benchmarked the performance of three different algorithms: recurrent neural network, Monte Carlo acceptance/rejection sampling, and Markov chain Monte Carlo. We tested and validated these approaches at the well locations by comparing classification predictions to the reference facies profile. The accuracy of the classification results is defined as the mismatch between the predictions and the log facies profile. Our study found that when the training data set of the neural network is large enough and the prior information about the transition probabilities of the facies in the Monte Carlo approach is not informative, machine-learning methods lead to more accurate solutions; however, the uncertainty of the solution might be underestimated. When some prior knowledge of the facies model is available, for example, from nearby wells, Monte Carlo methods provide solutions with similar accuracy to the neural network and allow a more robust quantification of the uncertainty, of the solution.


Author(s):  
Christoph Böhm ◽  
Jan H. Schween ◽  
Mark Reyers ◽  
Benedikt Maier ◽  
Ulrich Löhnert ◽  
...  

AbstractIn many hyper-arid ecosystems, such as the Atacama Desert, fog is the most important fresh water source. To study biological and geological processes in such water-limited regions, knowledge about the spatio-temporal distribution and variability of fog presence is necessary. In this study, in-situ measurements provided by a network of climate stations equipped, inter alia, with leaf wetness sensors are utilized to create a reference fog data set which enables the validation of satellite-based fog retrieval methods. Further, a new satellite-based fog detection approach is introduced which uses brightness temperatures measured by the Moderate Resolution Imaging Spectroradiometer (MODIS) as input for a neural network. Such a machine learning technique can exploit all spectral information of the satellite data and represent potential non-linear relationships. Compared to a second fog detection approach based on MODIS cloud top height retrievals, the neural network reaches a higher detection skill (Heidke skill score of 0.56 compared to 0.49). A suitable representation of temporal variability on subseasonal time scales is provided with correlations mostly greater than 0.7 between fog occurrence time series derived from the neural network and the reference data for individual climate stations, respectively. Furthermore, a suitable spatial representativity of the neural network approach to expand the application to the whole region is indicated. Three-year averages of fog frequencies reveal similar spatial patterns for the austral winter season for both approaches. However, differences are found for the summer and potential reasons are discussed.


2020 ◽  
Author(s):  
Ada Admin ◽  
Jialing Huang ◽  
Cornelia Huth ◽  
Marcela Covic ◽  
Martina Troll ◽  
...  

Early and precise identification of individuals with pre-diabetes and type 2 diabetes (T2D) at risk of progressing to chronic kidney disease (CKD) is essential to prevent complications of diabetes. Here, we identify and evaluate prospective metabolite biomarkers and the best set of predictors of CKD in the longitudinal, population-based Cooperative Health Research in the Region of Augsburg (KORA) cohort by targeted metabolomics and machine learning approaches. Out of 125 targeted metabolites, sphingomyelin (SM) C18:1 and phosphatidylcholine diacyl (PC aa) C38:0 were identified as candidate metabolite biomarkers of incident CKD specifically in hyperglycemic individuals followed during 6.5 years. Sets of predictors for incident CKD developed from 125 metabolites and 14 clinical variables showed highly stable performances in all three machine learning approaches and outperformed the currently established clinical algorithm for CKD. The two metabolites in combination with five clinical variables were identified as the best set of predictors and their predictive performance yielded a mean area value under the receiver operating characteristic curve of 0.857. The inclusion of metabolite variables in the clinical prediction of future CKD may thus improve the risk prediction in persons with pre- and T2D. The metabolite link with hyperglycemia-related early kidney dysfunction warrants further investigation.


2021 ◽  
Author(s):  
Nahid Hossain Taz ◽  
Abrar Islam ◽  
Ishrak Mahmud ◽  
Ehtashamul Haque ◽  
Md. Raqibur Rahman

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