scholarly journals The result of using Steriod during cardiopulmonary bypass in children undergoing cardiac surgery

2021 ◽  
Vol 35 ◽  
pp. 42-47
Author(s):  
Doan Phuc Hai ◽  
Ha Mai Huong ◽  
Vuong Hoang Dung
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Postoperative Infection ◽  
Pediatric Patients ◽  
Troponin T ◽  
Controlled Clinical Trial ◽  
High Dose ◽  
Randomized Controlled Clinical Trial ◽  
Randomized Controlled ◽  
Heart Hospital

The results of steroid in pediatric after cardiac surgery with steroid during extracorporeal circulation.  Objectives: Evaluating the clinical and laboratory characteristics in pediatric patients after cardiac surgery using steroid. Methods: A prospective, randomized, controlled clinical trial on 106 pediatric patients who underwent surgery requiring cardiopulmonary bypass at Hanoi Heart Hospital. Results: The rate of postoperative infection of the group using corticosteroids was 85.5%, the group not using corticosteroids was 96%. The rate of fever after surgery of the group using corticosteroids was 32.7%, the group not using corticosteroids was 35.3%. Troponin T concentration of group using corticosteroids was 1729.3 ± 1874.8 ng/L, group not using corticosteroids was 1855.0 ± 2658.0 ng/L. The time of mechanical ventilation and the time of recovery of the group using corticosteroids was 19.7 ± 23.6 hours and 61.8 ± 53.0 hours, the group not using corticosteroids was 19.8 ± 25.0 hours and 52 ,5 ± 39.1 hours. Conclusion: High-dose corticosteroids in this research did not cause adverse effects as mentioned in some studies, but did not bring any significant benefit to pediatric patients after cardiac surgery.

scholarly journals High-dose intravenous versus oral iron in blood donors with iron deficiency: The IronWoMan randomized, controlled clinical trial

2020 ◽  
Vol 39 (3) ◽  
pp. 737-745 ◽  
Author(s):  
Camilla Drexler ◽  
Susanne Macher ◽  
Ines Lindenau ◽  
Magdalena Holter ◽  
Martina Moritz ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Iron Deficiency ◽  
Blood Donors ◽  
Oral Iron ◽  
Controlled Clinical Trial ◽  
High Dose ◽  
Randomized Controlled Clinical Trial ◽  
Randomized Controlled

scholarly journals Comparison of Patient-Controlled Analgesia and Nurse-Controlled Infusion Analgesia after Cardiac Surgery

1994 ◽  
Vol 22 (6) ◽  
pp. 672-678 ◽  
Author(s):  
Paul S. Myles ◽  
Mark R. Buckland ◽  
Graham B. Cannon ◽  
Michael A. Bujor ◽  
Mark Langley ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Serum Cortisol ◽  
Tracheal Extubation ◽  
Morphine Consumption ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Patient Controlled Analgesia ◽  
Elective Cardiac Surgery ◽  
Randomized Controlled ◽  
Pain Scores

A randomized, controlled clinical trial was conducted on 72 patients undergoing elective cardiac surgery to compare patient-controlled analgesia (PCA) to nurse-titrated infusion of morphine. Pain and nausea scores were assessed at 5, 20, 32 and 44 hours after cardiopulmonary bypass. Serum cortisol estimations were performed at 24 and 48 hours, and morphine consumption was measured at 0-24 and 24-48 hours. There was no difference between pain scores (P=0.72), nausea scores (P=0.52), serum cortisol at 24 and 48 hours (P=0.32 and P=0.34), and morphine consumption at 0-24 and 24-48 hours (P=0.16 and P=0.12). There was also no difference in the time to tracheal extubation (P=0.79) and discharge from ICU (P=0.64). There was a significant association between pain and serum cortisol at 48 hours (P=0.023). This study also found a tenfold difference in the amount of morphine used (range = 11 to 108 mg), with no significant association with patient age or sex. We could find no significant benefit from the routine use of PCA in cardiac surgical patients.

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