scholarly journals Intraoperative Ultrasound-guided Excision of Cervical Lymph Nodes for Recurrent Differentiated Thyroid Cancer

2013 ◽  
Vol 5 (2) ◽  
pp. 45-49
Author(s):  
Ian C Bennett ◽  
Magdalena Biggar ◽  
Clement Wong ◽  
Michael Law

ABSTRACT As a result of sensitive thyroglobulin assays and widespread use of cervical ultrasound, endocrine surgeons are encountering patients with impalpable suspicious or frankly metastatic cervical lymph nodes in the follow-up phase after treatment for welldifferentiated thyroid cancer. The surgical excision of impalpable disease of recurrent or persistent thyroid cancer can represent a significant challenge which may require some means of intraoperative localization to ensure that affected nodes are removed. Surgeon-performed intraoperative ultrasound (IOUS) can be used for guiding excision of suspicious but impalpable cervical nodes. The IOUS-guided excision technique is described. The successful application of IOUS to localize and guide resection of impalpable nodal recurrences of papillary thyroid carcinoma in two patients is reported. The utilization of IOUS to guide resection of impalpable pathological nodes in the context of thyroid carcinoma is a safe and practical technique which avoids the need for additional localization procedures and unnecessary potential morbidity for the patient. How to cite this article Biggar M, Wong C, Law M, Bennett IC. Intraoperative Ultrasound-guided Excision of Cervical Lymph Nodes for Recurrent Differentiated Thyroid Cancer. World J Endoc Surg 2013;5(2):45-49.

BMC Surgery ◽  
2019 ◽  
Vol 18 (S1) ◽  
Author(s):  
Andrea Attard ◽  
Nunzia Cinzia Paladino ◽  
Attilio Ignazio Lo Monte ◽  
Nicola Falco ◽  
Giuseppina Melfa ◽  
...  

Thyroid ◽  
2006 ◽  
Vol 16 (2) ◽  
pp. 187-194 ◽  
Author(s):  
John C. Watkinson ◽  
Jayne A. Franklyn ◽  
Julie F.C. Olliff

2019 ◽  
Vol 25 (10) ◽  
pp. 1049-1055
Author(s):  
Berna İmge Aydoğan ◽  
Ugur Ünlütürk ◽  
Funda Seher Özalp Ateş ◽  
Murat Faik Erdoğan

Objective: The aim of this study was to assess and compare the diagnostic power of B-mode ultrasonography (US), power Doppler US (PD), and ultrasound elastography (USE) in detecting malignant lymph nodes (LNs) during follow-up of patients who were operated on for differentiated thyroid cancer (DTC). Methods: In this prospective study, a total of 103 cervical LNs having suspicious malignant features from 72 patients with DTC were examined using US, PD, and USE. USE scores were classified from 1 to 3 according to the presence of elasticity (1, soft; 2, intermediate; 3, hard). The strain ratios (SRs) of all LNs were calculated according to adjacent muscle tissue. Results: The most-sensitive ultrasonographic features were hilum loss and hypoechogenicity, with 94.4% and 80.6% sensitivity and 93.5% and 84.4% negative predictive value, respectively. The most-specific feature was the presence of cystic component, with 98.5% specificity and 85.7% positive predictive value. Presence of diffuse/chaotic or irregular vascularity in PD had 47.2% sensitivity and 83.6% specificity in predicting metastasis. In USE, the sensitivity and specificity of score 3 were 56.7% and 74.2%, respectively. The median SR of metastatic LNs was higher than that of benign LNs (median SR [min–max], 3.0 [0.16 and 29] vs. 1.89 [0.26 and 37.9]), but the difference was not significant ( P = .07). Multivariate logistic regression analyses revealed 4.9-, 6.6-, and 10-fold increases in metastasis risk for short/long axis ratio ≥0.5, nodal vascularity, and score 3 USE, respectively ( P<.05). Conclusion: While USE had higher sensitivity, PD had higher specificity in detecting malignant LNs, but none of these techniques was as sensitive and specific as gray-scale US features. Abbreviations: CI = confidence interval; DTC = differentiated thyroid cancer; LN = lymph node; LN-Tg = lymph node–thyroglobulin; NPV = negative predictive value; PD = power Doppler; PPV = positive predictive value; ROI = region of interest; SR = strain ratio; US = ultrasonography; USE = ultrasound elastography


Surgery ◽  
2002 ◽  
Vol 131 (4) ◽  
pp. 443-449 ◽  
Author(s):  
Ali S. Alzahrani ◽  
Majid Al Mandil ◽  
Mohammad A. Chaudhary ◽  
Mohammed Ahmed ◽  
Gamal Eldin Mohammed

PEDIATRICS ◽  
1973 ◽  
Vol 51 (5) ◽  
pp. 898-902
Author(s):  
Ben Z. Pilch ◽  
C. Ronald Kahn ◽  
Alfred S. Ketcham ◽  
Donald Henson

The authors present a case of mixed papillary and follicular thyroid carcinoma, metastatic to cervical lymph nodes, in a 20-year-old woman who had undergone diagnostic radioactive iodine procedures at 4 and 12 years of age. In this patient, calculation of radiation dose to the thyroid suggests that these procedures may have significantly increased the risk of development of thyroid malignancy.


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