scholarly journals Frozen Tissue Examination: Is It really no Longer of Use in Parathyroid Surgery? Single-center Retrospective Study on 97 Patients treated by minimally Invasive Approach

2017 ◽  
Vol 9 (2) ◽  
pp. 55-60
Author(s):  
Thomas Furderer, ◽  
Nicolas Bouviez, ◽  
Brice Paquette, ◽  
Gerard Landecy, ◽  
Bruno Heyd ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Minimally Invasive ◽  
Preoperative Imaging ◽  
Parathyroid Surgery ◽  
Single Center ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
Surgical Specimen ◽  
Frozen Tissue ◽  
The Mean

ABSTRACT Introduction Surgery, by minimally invasive approach, has become the gold standard in the treatment of primary hyperparathyroidism. However, the preoperative and intraoperative examinations to be performed are still subject to debate. The frozen tissue examination of the parathyroidectomy specimen is often criticized, as it is deemed difficult and noninformative in case of multiglandular disease. The primary objective was to study the result of the frozen tissue examination and its benefit in the operative strategy in minimally invasive surgery. Materials and methods This is a single-centre retrospective descriptive study on patients who underwent surgery for primary hyperparathyroidism between January 2011 and September 2013 at Besançon Centre Hospitalier Régional Universitaire (CHRU) [Regional University Hospital Center]. Inclusion criteria consisted of: At least one contributory preoperative imaging test, a focused approach, and an intraoperative frozen tissue examination with microscopic analysis of the surgical specimen. Results A total of 157 patients were treated for hyperparathyroidism and 97 were enrolled in the study. The mean age was 62.3 ± 13.7 years, mean serum calcium was 2.81 ± 0.24 mmol/L and the mean parathyroid hormone (PTH) level was 175 ± 120 pg/mL. Around 53 patients (54.6%) had concordant scintigraphic and ultrasound examinations while 20 patients (20.6%) had an isolated contributory scintigraphic examination, 21 patients (21.6%) had an isolated contributory cervical ultrasound and 3 patients had discordant examinations. The sensitivity of the preoperative imaging in case of concordance was 84.9% for the location of the diseased gland, and 92.4% for its lateralization. The sensitivity to ultrasound alone and scintigraphy alone was 61.9% and 65% respectively. Nearly 23 false positive imaging results were found in which 11 were corrected during surgery by the surgeon based on the macroscopic appearance. The frozen tissue examination of the surgical specimen changed the surgical strategy in 12 cases (12.4%): Six results of normal parathyroid gland (50%), four results of thyroid tissue (33.3%), and two cases of hyperplastic gland (16.7%). The results of the frozen tissue examination thus led to 12 exploratory cervicotomies, which revealed three ipsilateral adenomas (25%), six contralateral adenomas, and one adenoma included in the thyroid lobe, and enabled the surgeon to perform two subtotal parathyroidectomies for parathyroid hyperplasia. The mean duration of the frozen tissue examination was 24.2 ± 8.6 minutes and the cure rate is 100% for the population treated by minimally invasive approach. Conclusion In our experience, the frozen tissue examination enabled the surgeon to intraoperatively correct 12 erroneous imaging diagnoses, including two cases of parathyroid hyperplasia and thus to continue the exploration of other glands and immediately carry out the appropriate treatment. This is an interesting technique, but it is conditioned by the pathologist’s expertise. How to cite this article Furderer T, Bouviez N, Paquette B, Landecy G, Heyd B, Vienney G, Lakkis Z, Tauziede M. Frozen Tissue Examination: Is It really no Longer of Use in Parathyroid Surgery? Single-center Retrospective Study on 97 Patients treated by minimally Invasive Approach. World J Endoc Surg 2017;9(2):55-60.

Sutureless Aortic Valve Implantation through an Upper V-Type Ministernotomy: An Innovative Approach in High-Risk Patients

2013 ◽  
Vol 8 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Giovanni Concistrè ◽  
Antonio Miceli ◽  
Francesca Chiaramonti ◽  
Pierandrea Farneti ◽  
Stefano Bevilacqua ◽  
...  
Keyword(s):  
High Risk ◽  
Aortic Valve ◽  
Minimally Invasive ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
High Risk Patients ◽  
Risk Patients ◽  
The Mean ◽  
Valve Implantation

Objective Aortic valve replacement in minimally invasive approach has shown to improve clinical outcomes even with a prolonged cardiopulmonary bypass and aortic cross-clamp (ACC) time. Sutureless aortic valve implantation may ideally shorten operative time. We describe our initial experience with the sutureless 3f Enable (Medtronic, Inc, ATS Medical, Minneapolis, MN USA) aortic bioprosthesis implanted in minimally invasive approach in high-risk patients. Methods Between May 2010 and May 2011, thirteen patients with severe aortic stenosis underwent aortic valve replacement with the 3f Enable bioprosthesis through an upper V-type ministernotomy interrupted at the second intercostal space. The mean ± SD age was 77 ± 3.9 years (range, 72–83 years), 10 patients were women, and the mean ± SD logistic EuroSCORE was 15% ± 13.5%. Echocardiography was performed preoperatively, at postoperative day 1, at discharge, and at follow-up. Clinical data, adverse events, and patient outcomes were recorded retrospectively. The median follow-up time was 4 months (interquartile range, 2–10 months). Results Most of the implanted valves were 21 mm in diameter (19–25 mm). The CPB and ACC times were 100.2 ± 25.3 and 66.4 ± 18.6 minutes. At short-term follow-up, the mean ± SD pressure gradient was 14 ± 4.9 mm Hg; one patient showed trivial paravalvular leakage. No patients died during hospital stay or at follow-up. Conclusions The 3f Enable sutureless bioprosthesis implanted in minimally invasive approach through an upper V-type ministernotomy is a feasible, safe, and reproducible procedure. Hemodynamic and clinical data are promising. This innovative approach might be considered as an alternative in high-risk patients. Reduction of CPB and ACC time is possible with increasing of experience and sutureless evolution of actual technology.

scholarly journals Relevant Insertion Site Anatomy of the Conventus Distal Radius System

Hand ◽  
2017 ◽  
Vol 13 (3) ◽  
pp. 341-345
Author(s):  
Jacob Duncan ◽  
Marc Trzeciak
Keyword(s):  
Patient Satisfaction ◽  
Minimally Invasive ◽  
Distal Radius ◽  
Kirschner Wire ◽  
Insertion Site ◽  
Minimally Invasive Approach ◽  
Lateral Aspect ◽  
Invasive Approach ◽  
The Mean ◽  
Application Methods

Background: The Conventus Distal Radius System (DRS) is an intramedullary fixation scaffold inserted into the lateral aspect of the distal radius. The purpose of this study was to identify insertion site anatomy to illustrate risks associated with the minimally invasive nature of radial-sided implant application. Methods: Ten cadavers were utilized. Using fluoroscopy, the 1.1-mm Kirschner wire and template was introduced per manufacturer’s guidelines, access guide assembled, and dissection carried out to the superficial radial nerve (SRN) with preservation of the native location. The access guide marked the insertion location for the side-cut drill. This point was measured in relationship to structures nearby, including the SRN, brachioradialis (BR), lateral antebrachial cutaneous nerve (LABCN), and radial styloid (RS). Results: The large guide contacted the SRN in 4 of 10 cadavers and was volar to it in 6 of 10. When volar, the mean distance was 1.7 mm. The tip of the RS to the large access guide averaged 44.5 mm. The small guide contacted the SRN in 2 of 10, was volar to it in 4 of 10, and between the bifurcation in 4 of 10. When volar, the distance averaged 3.25 mm. When bifurcated, the distance from the small guide to both the dorsal and volar branches was 3.5 mm. The distance from the RS to the small guide averaged 37.8 mm. The LABCN was found in the field of dissection in 4 of 10 cadavers. Conclusions: Several structures are at risk during insertion of the Conventus DRS; thus, knowledge of the relevant anatomy of this minimally invasive approach is crucial to optimize outcomes and patient satisfaction, and to avoid nerve injury.

scholarly journals Primary Hyperparathyroidism in Older People: Surgical Treatment with Minimally Invasive Approaches and Outcome

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Chiara Dobrinja ◽  
Marta Silvestri ◽  
Nicolò de Manzini
Keyword(s):  
Primary Hyperparathyroidism ◽  
Minimally Invasive ◽  
Elderly Patients ◽  
Average Length ◽  
The Elderly ◽  
Preoperative Imaging ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
Average Length Of Stay ◽  
Operative Findings

Introduction. Elderly patients with primary hyperparathyroidism (pHPT) are often not referred to surgery because of their associated comorbidities that may increase surgical risk. The aim of the study was to review indications and results of minimally invasive approach parathyroidectomy in elderly patients to evaluate its impact on outcome.Materials and Methods. All patients of 70 years of age or older undergoing minimally approach parathyroidectomy at our Department from May 2005 to May 2011 were reviewed. Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies.Results and Discussion. 37 patients were analysed. The average length of stay was 2.8 days. 11 patients were discharged within 24 hours after their operation. Morbidity included 6 transient symptomatic postoperative hypocalcemias while one patient developed a transient laryngeal nerve palsy. Time elapsed from pHPT diagnosis to first surgical visit evidences that the elderly patients were referred after their disease had progressed.Conclusions. Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

Magnetic resonance imaging localization with cod liver oil capsules for the minimally invasive approach to small intradural extramedullary tumors of the thoracolumbar spine

2014 ◽  
Vol 21 (6) ◽  
pp. 882-885 ◽  
Author(s):  
Mazda K. Turel ◽  
Vedantam Rajshekhar
Keyword(s):  
Minimally Invasive ◽  
Operating Time ◽  
Thoracolumbar Spine ◽  
Cost Effective ◽  
Cod Liver Oil ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
Accurate Localization ◽  
Intradural Extramedullary ◽  
The Mean

Object Accurate intraoperative localization of small intradural extramedullary thoracolumbar (T-1 to L-3 level) spinal cord tumors is vital when minimally invasive techniques, such as hemilaminectomy, are used to excise these lesions. In this study, the authors describe a simple and effective method of preoperative MRI localization of small intradural extramedullary tumors using cod liver oil capsules. Methods Thirty-five patients with intradural tumors underwent preoperative MRI localization the evening prior to surgery. Patients were positioned prone in the MRI gantry, mimicking the intraoperative position. Nine capsules were placed in 3 rows to cover the lesion. This localization was used to guide the level for a minimally invasive approach using a hemilaminectomy to excise these tumors. Results The mean patient age was 51.5 ± 14.3 years, and the mean body mass index was 24.1 ± 3.5 kg/m2. Twenty-two tumors involved the thoracic spine, and 13 involved the upper lumbar spine from L-1 to L-3. The mean tumor size was 2.2 ± 1.0 cm. Localization was accurate in 34 patients (97.1%). Conclusions Accurate localization with the described method is quick, safe, cost-effective, and noninvasive with no exposure to radiation. It also reduces operating time by eliminating the need for intraoperative fluoroscopy.

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