scholarly journals Intrauterine Growth Restriction: Guidelines for the use of Obstetrical Ultrasound

2016 ◽  
Vol 10 (3) ◽  
pp. 350-351
Author(s):  
Giampaolo Mandruzzato
Keyword(s):  
Fetal Growth ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcome ◽  
Obstet Gynecol ◽  
Growth Restriction ◽  
Perinatal Medicine ◽  
Mortality And Morbidity ◽  
Intrauterine Growth ◽  
The Poor ◽  
Obstetrical Ultrasound

ABSTRACT Intrauterine growth restriction (IUGR) is a major problem in perinatal medicine. It is the second cause of perinatal mortality and morbidity after prematurity and the two conditions are frequently associated. The principal cause of the poor perinatal outcome is represented by the chronic fetal hypoxemia (FCH) that occurs in 30 to 35% of IUGR fetuses. In order to improve significantly the clinical outcome a timely recognition and a proper management is fundamental. Today the method of choice for monitoring the fetal growth and detect any deviation is represented by serial fetal ulrtasound biometry. After suspicion or recogntion of fetal growth restriction it is necessary to assess the characteristics of the maternal-fetal exchanges in order to detedct or exlude the presence of chronic fetal hypoxemia. How to cite this article Mandruzzato G. Intrauterine Growth Restriction: Guidelines for the use of Obstetrical Ultrasound. Donald School J Ultrasound Obstet Gynecol 2016;10(3):350-351

scholarly journals Analysis of fetal growth restriction in pregnancy in subjects attending in an obstetric clinic of a tertiary care teaching hospital

2018 ◽  
Vol 7 (3) ◽  
pp. 973
Author(s):  
Ashish Seal ◽  
Arup Dasgupta ◽  
Mousumi Sengupta ◽  
Rinini Dastider ◽  
Sukanta Sen
Keyword(s):  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
Intrauterine Growth Restriction ◽  
Tertiary Care ◽  
Growth Restriction ◽  
Growth Potential ◽  
Crown Rump Length ◽  
Mortality And Morbidity ◽  
Intrauterine Growth ◽  
In Pregnancy

Background: Intrauterine growth restriction (IUGR) is defined as fetal growth less than the normal growth potential of a specific infant because of genetic or environmental factors. Fetal growth restriction or intrauterine growth restriction is one of the leading causes of perinatal mortality and morbidity in newborns. Fetal growth restriction is a complex multifactorial condition resulting from several fetal and maternal disorders. Objective of present study was to find out incidence of IUGR and assessment and evaluation of different important changes in IUGR.Methods: Women who attended the Obstetric OPD in their 1st trimester of pregnancy and those who were thought would be able to visit the antenatal clinic for their fortnightly check-up regularly were screened for intrauterine foetal growth retardation. Women with irregular and uncertain menstrual history and where the 1st trimester USG foetal crown rump length did not corroborate with the menstrual gestational age were excluded from this study.Results: Incidence of IUGR was 18.2% and 84% were found to be asymmetrical. IUGR was found to be double among primigravids and women above 30 years. It had been observed that IUGR was associated with certain conditions like short stature (52%), pregnancy induced hypertension (24%) and anaemia (12%).Conclusions: Thus, early USG screening along with robust screening for maternal BMI, nutritional status, and anaemia can assist the obstetric team in providing early diagnosis, prompt intervention, and better outcome in pregnancy with fetal growth restriction.

scholarly journals Understanding intrauterine growth restriction (IUGR): a review

2016 ◽  
Vol 2 (4) ◽  
pp. 31-37 ◽  
Author(s):  
Pankaj Verma ◽  
Hema Chaudhary
Keyword(s):  
Intrauterine Growth Restriction ◽  
Normal Growth ◽  
Bed Rest ◽  
Growth Restriction ◽  
Growth Potential ◽  
Biomedical Sciences ◽  
Pharmacological Management ◽  
Mortality And Morbidity ◽  
Intrauterine Growth ◽  
Aryl Hydrocarbon

Intrauterine Growth Restriction (IUGR) is defined as the inability of a fetus to gain the normal growth potential due to maternal-placental-fetal factors. These factors mainly involve metabolic disorders, infections, substance abuse and exposure to harmful substances. Incidence of IUGR is higher in developing countries. Proper diagnosis at suitable time is necessary for proper treatment and management. Although, the mechanism is not clear but oxidative stress, immunological factors, aryl hydrocarbon receptor and adduct formation are some pathways which are involved in IUGR. The aftermaths of IUGR involves post-birth complications, perinatal mortality and morbidity. Therefore, management and treatment involves use of both pharmacological (Tocolytics, Corticosteroids, antibiotics) and non-pharmacological methods (bed rest, cerclage). This review highlights the possible risk factors, mechanisms, other biochemical pathways involved, as well as pharmacological and non-pharmacological management of IUGR.Journal of Biomedical Sciences. 2015;2(4):31-37

Associations of Intrauterine Growth Restriction Among Term Infants and Maternal Pregnancy Intendedness, Initial Happiness About Being Pregnant, and Sense of Control

PEDIATRICS ◽  
2003 ◽  
Vol 111 (Supplement_1) ◽  
pp. 1171-1175
Author(s):  
Sharon Durousseau ◽  
Gilberto F. Chavez
Keyword(s):  
Confidence Interval ◽  
Psychosocial Factors ◽  
Intrauterine Growth Restriction ◽  
Odds Ratio ◽  
Growth Restriction ◽  
Sense Of Control ◽  
Term Infants ◽  
Mortality And Morbidity ◽  
Intrauterine Growth ◽  
Pregnancy Intendedness

Objective. Term infants (≥37 weeks’ gestation) who weigh <2500 g have intrauterine growth restriction (IUGR) and have a higher risk of mortality and morbidity. Little is known about how psychosocial factors affect the risk of IUGR. We examined the association between IUGR and maternal pregnancy intendedness, initial happiness about becoming pregnant, and maternal sense of control. Methods. We analyzed data from a survey of California mothers aged ≥15 years with term live births in 1999 and 2000 (N = 5961). Mothers were asked about pregnancy intendedness before pregnancy, initial happiness about becoming pregnant, and maternal sense of control, assessed by a standardized scale. We examined the association of having an infant with IUGR and these factors in univariate and multivariate analyses. Results. Mothers with low sense of control (3.0%) and average sense of control (2.7%) were more likely to have an infant with IUGR than mothers with high sense of control (1.8%; odds ratio: 1.8; 95% confidence interval: 1.2–2.9; and odds ratio: 1.6; 95% confidence interval: 1.0–2.5). After multivariate analysis, we found no significant association between sense of control and IUGR. We also found no significant association between IUGR and pregnancy intendedness and happiness about becoming pregnant. Conclusions. We found no statistically significant association between IUGR and maternal pregnancy intendedness, initial happiness about becoming pregnant, and maternal sense of control. Although research should continue to explore associations between psychosocial factors and IUGR, prenatal care programs should focus on known risk factors for IUGR.

P07.13: Intrauterine growth restriction: correlation between perinatal outcome and Doppler study of middle cerebral artery

2009 ◽  
Vol 34 (S1) ◽  
pp. 205-206
Author(s):  
L. Almeida Toledano ◽  
L. Pallarès Porta ◽  
L. Lopez ◽  
L. Alué Ponti ◽  
J. Sabrià ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcome ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Doppler Study

Placental expression of the obesity-associated gene FTO is reduced by fetal growth restriction but not by macrosomia in rats and humans

2012 ◽  
Vol 4 (2) ◽  
pp. 134-138 ◽  
Author(s):  
S. Mayeur ◽  
O. Cisse ◽  
A. Gabory ◽  
S. Barbaux ◽  
D. Vaiman ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Fetal Growth ◽  
Genetic Variants ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Intrauterine Growth ◽  
Placental Villi ◽  
Insight Into ◽  
Epigenetic Processes

Genetic variants in the FTO (fat mass- and obesity-associated) gene have the highest association of all obesity-associated genes. Its placental expression was shown to relate to birth weight, suggesting that it may participate in the control of fetal weight gain. To gain more insight into the implication of FTO in fetal growth, we measured its placental expression in samples including extremes of abnormal fetal growth, such as after intrauterine growth restriction (IUGR) or macrosomia in both rats and humans. In rats, fetal growth was modulated by maternal nutritional modifications. In humans, placental villi were collected from pathological pregnancies (i.e. with IUGR or fetal macrosomia). Placental FTO mRNA expression was reduced by IUGR but was not significantly affected by macrosomia in either rats or humans. Our data suggest that placental FTO may participate in interactions between the in utero environment and the control of fetal growth under IUGR conditions by modulating epigenetic processes.

Sign in / Sign up

Export Citation Format

Share Document