Pain Control and Quality of Life after Peripheral Neurectomy in Patients with Refractory Trigeminal Neuralgia

Object There are various surgical treatment alternatives for trigeminal neuralgia (TN), but there is no single scale that can be used uniformly to assess and compare one type of intervention with the others. In this study the objectives were to determine factors associated with pain control, pain-free survival, residual pain, and recurrence after gamma knife surgery (GKS) treatment for TN, and to correlate the patients' self-reported quality of life (QOL) and satisfaction with the aforementioned factors. Methods Between the years 2000 and 2004, the authors treated 81 patients with medically refractory TN by using GKS. Fifty-two patients responded to a questionnaire regarding pain control, activities of daily living, QOL, and patient satisfaction. The median follow-up duration was 16.5 months. Twenty-two patients (42.3%) had complete pain relief, 14 (26.9%) had partial but satisfactory pain relief, and in 16 patients (30.8%) the treatment failed. Seven patients (13.5%) reported a recurrence during the follow-up period, and 25 (48.1%) reported a significant (> 50%) decrease in their pain within the 1st month posttreatment. The mean decrease in the total dose of pain medication was 75%. Patients' self-reported QOL scores improved 90% and the overall patient satisfaction score was 80%. Conclusions The authors found that GKS is a minimally invasive and effective procedure that yields a favorable outcome for patients with recurrent or refractory TN. It may also be offered as a first-line surgical modality for any patients with TN who are unsuited or unwilling to undergo microvascular decompression.

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Gabapentin Supplemented With Ropivacain Block of Trigger Points Improves Pain Control and Quality of Life in Trigeminal Neuralgia Patients When Compared With Gabapentin Alone

Clinical Journal of Pain ◽

10.1097/ajp.0b013e318158011a ◽

2008 ◽

Vol 24 (1) ◽

pp. 64-75 ◽

Cited By ~ 46

Author(s):

Laurinda Lemos ◽

Sara Flores ◽

Pedro Oliveira ◽

Armando Almeida

Keyword(s):

Quality Of Life ◽

Trigeminal Neuralgia ◽

Pain Control ◽

Trigger Points

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Evaluation of Satisfaction with Life and Quality of Life of Elderly People with Trigeminal Neuralgia

The International Annals of Medicine ◽

10.24087/iam.2018.2.5.508 ◽

2018 ◽

Vol 2 (5) ◽

Author(s):

Ahmet Taylan Çebi

Keyword(s):

Quality Of Life ◽

Trigeminal Neuralgia ◽

Elderly People ◽

Satisfaction With Life

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Does the surgical intervention for trigeminal neuralgia refractory to pharmacotherapy improve quality-of-life? – A systematic review

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2021.03.003 ◽

2021 ◽

Author(s):

Dr. Cathrine Diana ◽

Dr. Rudra Deo Kumar ◽

Dr. Ranjeet Bodh ◽

Dr. Saroj Kumari

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Trigeminal Neuralgia ◽

Surgical Intervention ◽

Improve Quality

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What makes CT guided radiofrequency ablation for osteoid osteoma superior to open surgery in terms of pain control and patient’s quality of life?

The Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1016/j.ejrnm.2015.05.015 ◽

2015 ◽

Vol 46 (4) ◽

pp. 949-955 ◽

Cited By ~ 2

Author(s):

Mostafa Mohamed Mostafa Elian ◽

Ahmed Fathy Sadek

Keyword(s):

Quality Of Life ◽

Radiofrequency Ablation ◽

Osteoid Osteoma ◽

Pain Control ◽

Open Surgery ◽

Ct Guided

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A Prospective Multicentre Study to Evaluate the Efficacy and Tolerability of Osmotic Release Oral System (Oros®) Hydromorphone in Opioid-Naive Cancer Patients: Results of the Korean South West Oncology Group Study

Pain Research and Management ◽

10.1155/2015/458389 ◽

2015 ◽

Vol 20 (6) ◽

pp. 293-299 ◽

Cited By ~ 3

Author(s):

Eun-Kee Song ◽

Hyunjeong Shim ◽

Hye-Suk Han ◽

DerSheng Sun ◽

Soon-Il Lee ◽

...

Keyword(s):

Quality Of Life ◽

Pain Relief ◽

Cancer Pain ◽

Pain Intensity ◽

Cancer Patients ◽

Pain Control ◽

Intensity Difference ◽

Front Line ◽

Long Acting

BACKGROUND: Osmotic release oral system (OROS®) hydromorphone is a potent, long-acting opioid analgesic, effective and safe for controlling cancer pain in patients who have received other strong opioids. To date, few studies have examined the efficacy of hydromorphone for pain relief in opioid-naive cancer patients.OBJECTIVES: A prospective, open-label, multicentre trial was conducted to determine the efficacy and tolerability of OROS hydromorphone as a single and front-line opioid therapy for patients experiencing moderate to severe cancer pain.METHODS: OROS hydromorphone was administered to patients who had not previously received strong, long-acting opioids. The baseline evaluation (visit 1) was followed by two evaluations (visits 2 and 3) performed two and 14 weeks later, respectively. The starting dose of OROS hydromorphone was 4 mg/day and was increased every two days when pain control was insufficient. Immediate-release hydromorphone was the only accepted alternative strong opioid for relief of breakthrough pain. The efficacy, safety and tolerability of OROS hydromorphone, including the effects on quality of life, and patients’ and investigators’ global impressions on pain relief were evaluated. The primary end point was pain intensity difference (PID) at visit 2 relative to visit 1 (expressed as %PID).RESULTS: A total of 107 patients were enrolled in the present study. An improvement in pain intensity of >50% (≥50% PID) was observed in 51.0% of the full analysis set and 58.6% of the per-protocol set. The mean pain score, measured using a numerical rating scale, was significantly reduced after two weeks of treatment, and most adverse events were manageable. Quality of life also improved, and >70% of patients and investigators were satisfied with the treatment.CONCLUSIONS: OROS hydromorphone provided effective pain relief and improved quality of life in opioid-naive cancer patients. As a single and front-line treatment, OROS hydromorphone delivered rapid pain control.

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Improving Quality of Life Through Pain Control

Clinical Journal of Oncology Nursing ◽

10.1188/13.cjon.117-118 ◽

2013 ◽

Vol 17 (2) ◽

pp. 117-118

Author(s):

Valerie Burger ◽

James T. D'Olimpio

Keyword(s):

Quality Of Life ◽

Pain Control

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Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain

Pain Research and Management ◽

10.1155/2020/7565962 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8

Author(s):

Yinxia Wang ◽

Ligang Xing

Keyword(s):

Quality Of Life ◽

Side Effects ◽

Cancer Pain ◽

Cancer Patients ◽

Pain Control ◽

Analgesic Drugs ◽

Oxycodone Hydrochloride ◽

Radiation Esophagitis

Radiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from pain flare or radiotherapy-induced side effects such as radiation esophagitis, enteritis, and mucositis. Pain control is reported to be inadequate during the whole course of radiotherapy (before, during, and after radiotherapy), and quality of life is seriously affected. Hence, radiotherapy is suggested to be combined with analgesic drugs in clinical guidelines. Previous studies have shown that radiotherapy combined with oxycodone hydrochloride can effectively alleviate cancer pain. In this review, we firstly presented the necessity of analgesia during the whole course of radiotherapy. We also sketched the role of oxycodone hydrochloride in radiotherapy of bone metastases and radiotherapy-induced oral mucositis. Finally, we concluded that oxycodone hydrochloride shows good efficacy and tolerance and could be used for pain management before, during, and after radiotherapy.

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Application of quality control circle in the treatment of moderate cancer pain in inpatients

Japanese Journal of Clinical Oncology ◽

10.1093/jjco/hyz214 ◽

2020 ◽

Vol 50 (5) ◽

pp. 581-585

Author(s):

Yehuan Liu ◽

Beibei Lin

Keyword(s):

Quality Of Life ◽

Quality Control ◽

Cancer Pain ◽

Pain Control ◽

Management Tool ◽

Control Group ◽

Observation Group ◽

Patients With Cancer ◽

Significant Difference

Abstract Context Pain is one of the most common and intolerable symptoms in cancer patients. But cancer pain control is still negative in China. Objectives This paper explores the application of quality control circle in the treatment of cancer pain in inpatients to improve the quality of life of patients with cancer pain. Method Established a quality control circle group to analyze the current status of cancer pain control in inpatients with moderate cancer pain, set goals, formulate corresponding countermeasures and implement and review them in stages. The plan-do-check-act method was cyclically applied. The Brief Pain Inventory was used to evaluate the cancer pain status of patients with cancer pain hospitalized before (January to April 2016) and after (September to December 2016) the implementation of quality control circle activities. Results The pain control effect of the observation group was significantly better than that of the control group. The mean (standard deviation) of pain severity and pain interference in the observation group were significantly lower than those in the control group (6.21 [2.86] vs 4.31 [2.25], 10.54 [4.10] vs 7.25 [3.77]). There was significant difference after the implementation of quality control circle (P < 0.01). Conclusion Quality control circle activities are used to manage patients with cancer pain, to improve the situation of pain control and to improve the quality of life of patients. This management tool and method is worthy of clinical promotion and application.

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