scholarly journals Comparative Evaluation of Guided Tissue Regeneration with use of Collagen-based Barrier Freeze-Dried Dura Mater Allograft for Mandibular Class 2 Furcation Defects (A Comparative Controlled Clinical Study)

2012 ◽  
Vol 13 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Arvind Agarwal ◽  
Brijesh Ruparelia ◽  
Sandeep Patel ◽  
Ajay Kubavat
Keyword(s):  
Dura Mater ◽  
Tissue Regeneration ◽  
Control Site ◽  
Guided Tissue Regeneration ◽  
Hard Tissue ◽  
Pocket Depth ◽  
Freeze Dried ◽  
Furcation Defects ◽  
Tissue Changes ◽  
Controlled Clinical Study

ABSTRACT Aim The aim of periodontal surgery is complete regeneration. The present study was designed to evaluate and compare clinically soft tissue changes in form of probing pocket depth, gingival shrinkage, attachment level and hard tissue changes in form of horizontal and vertical bone level using resorbable membranes. Materials and methods Twelve subjects with bilateral class 2 furcation defects were selected. After initial phase one treatment, open debridement was performed in control site while freezedried dura mater allograft was used in experimental site. Soft and hard tissue parameters were registered intrasurgically. Nine months reentry ensured better understanding and evaluation of the final outcome of the study. Results Guided tissue regeneration is a predictable treatment modality for class 2 furcation defect. There was statistically significant reduction in pocket depth as compared to control (p < 0.01). There is statistically significant increase in periodontal attachment level within control and experimental sites showed better results (p < 0.01). For hard tissue parameter, significant defect fill resulted in experimental group, while in control group, less significant defect fill was found in horizontal direction and nonsignificant defect fill was found in vertical direction. Conclusion The results showed statistically significant improvement in soft and hard tissue parameters and less gingival shrinkage in experimental sites compared to control site. Clinical significance The use of FDDMA in furcation defects helps us to achieve predictable results. This cross-linked collagen membrane has better handling properties and ease of procurement as well as economic viability making it a logical material to be used in regenerative surgeries. How to cite this article Patel S, Kubavat A, Ruparelia B, Agarwal A, Panda A. Comparative Evaluation of Guided Tissue Regeneration with use of Collagen-based Barrier Freeze-Dried Dura Mater Allograft for Mandibular Class 2 Furcation Defects (A Comparative Controlled Clinical Study). J Contemp Dent Pract 2012;13(1):11-15.

scholarly journals Adjunctive Systemic Antimicrobial Therapy vs Asepsis in Conjunction with Guided Tissue Regeneration: A Randomized, Controlled Clinical Trial

2016 ◽  
Vol 17 (1) ◽  
pp. 3-6 ◽  
Author(s):  
Mahmoud Abu-Ta'a
Keyword(s):  
Clinical Trial ◽  
Tissue Regeneration ◽  
Bone Allograft ◽  
Guided Tissue Regeneration ◽  
Controlled Clinical Trial ◽  
Pocket Depth ◽  
Freeze Dried ◽  
Attachment Level ◽  
Preservation Technique ◽  
Postoperative Discomfort

ABSTRACT Aim This randomized clinical trial compares the usefulness of adjunctive antibiotics, while strict asepsis was followed during periodontal surgery involving guided tissue regeneration. Materials and methods Two groups of 20 consecutive patients each with advanced periodontal disease were randomly assigned to treatment. They displayed one angular defect each with an intrabony component ≥3 mm, probing pocket depth and probing attachment level (PAL) ≥7 mm. Test group included 13 males, mean age 60 years, treated with enamel matrix derivative (EMD) and demineralized freeze-dried bone allograft with modified papilla preservation technique, received oral amoxicillin 1 gm, 1 hour preoperatively and 2 gm for 2 days postoperatively. Control group included 10 males, mean age 57 years, treated with EMD and demineralized freeze-dried bone allograft with modified papilla preservation technique, received no antibiotics. Outcome measures were clinical attachment level (CAL) gain, residual periodontal pocket depth (res. PD), gingival recession (GR), bleeding on probing (BOP), adverse events and postoperative complications. Patients were followed up to 12 months after periodontal surgery involving guided tissue regeneration. Results There were no significant differences between both groups for CAL gain, res. PD, GR, BOP nor other clinical parameters, though patients’ subjective perception of postoperative discomfort was significantly smaller in the group receiving antibiotics. Conclusion Antibiotics do not provide significant advantages concerning clinical periodontal parameters nor concerning postoperative infections in case of proper asepsis. It does, on the contrary, reduce postoperative discomfort. Clinical significance Regarding the results of this study, adjunctive systemic antibiotics in combination with guided tissue regeneration may be useful in reducing postoperative discomfort but may not be helpful for improving periodontal regeneration outcomes. How to cite this article Abu-Ta'a M. Adjunctive Systemic Antimicrobial Therapy vs Asepsis in Conjunction with Guided Tissue Regeneration: A Randomized, Controlled Clinical Trial. J Contemp Dent Pract 2016;17(1):3-6.

scholarly journals Clinical Management of Endo-Perio Lesion Through Guided Tissue Regeneration: a 5 Year Follow-Up

2021 ◽  
pp. 151-156
Author(s):  
Munis Mukhtar ◽  
Maaz Asad ◽  
Asaad Javaid Mirza
Keyword(s):  
Tissue Regeneration ◽  
Bone Allograft ◽  
Clinical Findings ◽  
Guided Tissue Regeneration ◽  
Collagen Membrane ◽  
Pocket Depth ◽  
Radiographic Findings ◽  
Freeze Dried ◽  
Distal Surface

Progressive periodontal disease causes loss of supporting structures of teeth resulting in deep bony defects. In this case a report of 22-year old female patient is being presented with clinical findings of vertical bone loss in two adjacent teeth, on distal surface of  2nd  upper right premolar and mesial surface of upper right 1st molar. Root canal treatment, non-surgical periodontal therapy followed by guided tissue regeneration was carried out using decalcified freeze-dried bone allograft (DFDBA) and collagen membrane. Analysis of clinical and radiographic findings showed marked reduction in pocket depth up to 12mm with hard tissue repair on 3-month, 2-year and 5- year follow ups.

Guided Tissue Regeneration in Human Class II Furcation Defects Using a Diphenylphosphorylazide-Cross-Linked Collagen Membrane: A Consecutive Case Series

2003 ◽  
Vol 74 (7) ◽  
pp. 1071-1079 ◽  
Author(s):  
Charles S. Zahedi ◽  
S. Asghar Miremadi ◽  
Gérard Brunel ◽  
Eric Rompen ◽  
Jean-Pierre Bernard ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Case Series ◽  
Class Ii ◽  
Guided Tissue Regeneration ◽  
Collagen Membrane ◽  
Consecutive Case ◽  
Human Class ◽  
Furcation Defects
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