scholarly journals Dual Ectopic Thyroid: An Uncommon Imaging Diagnosis

2015 ◽  
Vol 49 (2) ◽  
pp. 83-84
Author(s):  
Nidhi Prabhakar ◽  
Vivek Gupta ◽  
Naresh Panda

ABSTRACT Ectopic thyroid means presence of thyroid gland tissue in abnormal position. Dual ectopic thyroid is the presence of thyroid gland tissue in two different abnormal locations. It is a rare entity. We report a case of 17-year-old girl who presented with a gradually increasing swelling in the upper neck. Her thyroid tests were abnormal, with mildly reduced T3 and T4 levels and increased TSH levels. Ultrasound revealed an isoechoic homogenous lesion in the intermuscular planes, in the infrahyoid neck. Contrast-enhanced computed tomography (CECT) of neck was performed which showed two similarly homogenously enhancing lesions, one in the base of tongue and another in the infrahyoid neck. Thyroid gland was not seen in its normal location. On the basis of these findings, diagnosis of dual ectopic thyroid was made. Patient was managed with thyroid hormone replacement therapy to manage hypothyroidism and decrease the size of swelling. How to cite this article Prabhakar N, Gupta V, Panda N, Khandelwal N. Dual Ectopic Thyroid: An Uncommon Imaging Diagnosis. J Postgrad Med Edu Res 2015;49(2):83-84.

2020 ◽  
Vol 18 (13) ◽  
pp. e157 ◽  
Author(s):  
Mingyu Chen ◽  
Jiahao Hu ◽  
Xiujun Cai

2017 ◽  
Vol 8 (5) ◽  
pp. 30-34
Author(s):  
Olga V. Sokolova ◽  
Orazmurad D. Yagmurov ◽  
Ruslan A. Nasyrov

A retrospective analysis of acts of forensic medical autopsies from the archive of St. Petersburg GBUS BSME and a histological study of thyroid gland tissue in 188 cases (95 women and 93 men) were carried out with statistical processing of the obtained results for the purpose of studying and assessing the morphological changes in the main components of the histohematological barrier of thyroid gland tissue in cases of the sudden cardiac death from alcoholic cardiomyopathy. The decrease in the weight of the thyroid gland in the investigated cases and the revealed morphological signs, indicative of a decrease in the memory function of the thyroid gland were found and can be caused by the prolonged toxic effect of ethanol and its metabolites. Morphological changes in the endothelial lining of the vessels of the microcirculatory bed are caused both by the direct cytotoxic action of ethanol and its metabolites and by the action of mediators, the release of which occurs as a result of stimulation of the reactive cells, which leads to swelling, deformation and increased activity of endothelial cell membranes with the expansion of intercellular spaces and the development of increased permeability of the endothelial lining, which, in its turn, contributes to disruption of electrolyte transport and nutrients transport with changes trophism thyroid gland tissue, which is a substrate for the appearance of dystrophic and necrobiotic processes in main structural components of the histogematogenous barrier of the thyroid gland. The revealed morphological changes in thyroid gland tissue in cases of death from alcoholic cardiomyopathy have a non-specific nature and should be considered in conjunction with other visceral manifestations that are a reflection of alcohol intoxication during the chronic alcoholism.


Author(s):  
Alina Sultanova ◽  
Maksims Èistjakovs ◽  
Egils Cunskis ◽  
Katerina Todorova ◽  
Russy Russev ◽  
...  

Abstract Human herpesvirus-6 (HHV-6) is a ubiquitous betaherpesvirus with immunomodulating properties that have been suggested to play an important role in the development of several autoimmune disorders. Although the primary targets for HHV-6 replication, both in vitro and in vivo, are CD4+ and CD8+ T lymphocytes, some studies have reported the presence of HHV-6 sequences in different solid organs, including in the thyroid gland, showing possible involvement of this herpesvirus in development of autoimmune thyroid disease. The aim of this study was to determine loads of HHV-6 in thyroid gland tissue in comparison to those in peripheral blood of patients with autoimmune thyroiditis. Seven patients [women mean age 45 (28-65)] with histologically confirmed autoimmune thyroiditis were enrolled in this study. Fluorescence-activated cell sorting was used to distinguish and sort lymphocyte populations from peripheral blood mononuclear cells of patients. HHV-6 load was determined by real-time PCR for peripheral blood and thyroid gland tissue samples. Additionally, all results from molecular analyses were compared with histological results obtained by light microscopy. Viral load was detected only in one (46 viral copies/ 1×106cells) blood sample; others were under the detection limit of the used kit. However, in all HHV-6 positive tissue samples viral load was detected in the range of 132-1620 viral copies/106 cells. Substantial HHV-6 load in lymphocyte subpopulations was detected in two of seven patients. HHV-6 load was detected in NK and CD95+ cells of two patients. The obtained results show that thyroid gland cells (tyrocytes) act as target cells for HHV-6.


2021 ◽  
Vol 8 (8) ◽  
pp. 2457
Author(s):  
Ashok Kumar G. ◽  
Murugan Arumugam ◽  
Manoj Karthik S. ◽  
Ananthakrishnan Nilakanta

The ectopic tissue of the thyroid gland along the descent of thyroglossal duct is a rare congenital aberration with or without the presence of normal thyroid gland. Single or dual ectopic thyroid has been reported. Three ectopic focuses at different locations are extremely rare. We present a rare case report of twenty years old female who presented with swelling over the anterior aspect of the neck mimicking thyroglossal cyst. Up on imaging evaluation ectopic thyroid at three different levels were diagnosed by computed tomography (CT) neck. Hence surgery was avoided and patient was managed with thyroxine supplement and follow up.


2018 ◽  
pp. bcr-2018-225506 ◽  
Author(s):  
Claudia Matta-Coelho ◽  
Sara Donato ◽  
Manuel Carvalho ◽  
Helena Vilar

1967 ◽  
Vol 16 (4) ◽  
pp. 410-416
Author(s):  
U. Bigozzi ◽  
M. Bigazzi ◽  
R. Guazzelli ◽  
F. Melani

SUMMARYThe Authors describe the case of juvenile hypothyroidism with goiter caused by a congenital defect in the synthesis of the thyroid hormones. The picture of thyroid uptake curve, cromatographic separation of thyroid hormones in serum and of thyroid gland tissue, and the PBI concentration, suggest to include the case among the iodothyrosine dehalogenase defects. Such a defect, though very attenuate, has been found in the patient's mother too. From a genetic point of view, Authors suggest to consider both cases heterozygous expression of the defect; though in the daugther this defect is more accentuate.


2014 ◽  
Vol 36 (6) ◽  
pp. 556-558 ◽  
Author(s):  
Vinko Marković ◽  
Gordana Glavina ◽  
Davor Eterović ◽  
Ante Punda ◽  
Dubravka Brdar

Author(s):  
Shigenori Nakamura ◽  
Teruyuki Masuda ◽  
Masatoshi Ishimori

Summary We report a case of a 15-year-old girl with a midline neck mass that was first noted 2 or 3 years previously. She had been treated with levothyroxine (L-T4) for congenital hypothyroidism until 11 years of age. Ultrasonography revealed an atrophic right thyroid (1.0 × 1.6 × 2.6 cm in size) and a mass (2.3 × 1.0 × 3.5 cm in size) in the upper part of the neck. No left lobe of the thyroid was detected. On further evaluation, Tc-99m pertechnetate thyroid scintigraphy and CT showed ectopic thyroid tissue in the lingual region and infrahyoid region. Thus, she was diagnosed as having dual ectopic thyroid and thyroid hemiagenesis. The atrophic right thyroid was thought be non-functional. Treatment with L-T4 was started to reduce the size of the dual ectopic thyroid tissue. This may be the first reported case of dual ectopic thyroid associated with hemiagenesis detected only by ultrasonography. Learning points: Ultrasonography can confirm the presence or absence of orthotopic thyroid tissue in patients with ectopic thyroid. The cause of congenital hypothyroidism should be examined. Clinical manifestation of ectopic thyroid may appear when the treatment with L-T4 is discontinued. Annual follow-up is needed in all children when their thyroid hormone replacement is stopped.


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