scholarly journals Acceptance of illness as a mediator of the relationship between neurological disability and health-related quality of life of people with multiple sclerosis

2020 ◽  
Vol 15 (1-2) ◽  
pp. 13-20
Author(s):  
Joanna Dymecka ◽  
Rafał Gerymski
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Health Related Quality ◽  
Disability And Health ◽  
Neurological Disability ◽  
Related Quality ◽  
Health Related ◽  
Acceptance Of Illness ◽  
The Relationship

scholarly journals Biomedical Variables and Adaptation to Disease and Health-Related Quality of Life in Polish Patients with MS

2018 ◽  
Vol 15 (12) ◽  
pp. 2678 ◽  
Author(s):  
Joanna Dymecka ◽  
Mariola Bidzan
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Mood Disorders ◽  
Upper Limb ◽  
Lower Limb ◽  
Health Related Quality ◽  
Neurological Disability ◽  
Related Quality ◽  
Health Related

The aim of this research was to assess the level of adaptation to multiple sclerosis (Sclerosis multiplex; MS) and health-related quality of life (HRQoL) of the study population as well as to determine the relationship between biomedical factors related to the course of multiple sclerosis, adaptation to the disease, and HRQoL. Analysis of medical records, clinical and psychological interviews, the Extended Disability Status Scale (EDSS), Guy’s Neurological Disability Scale (GNDS), the Acceptance of Illness Scale (AIS), and the Multiple Sclerosis Impact Scale 29 (MSIS-29) were collected from 137 patients with MS. It was found that there was a relation between motor impairment, neurological disability, adaptation to illness, and HRQoL; it was also found that there were negative correlations between adaptation to illness and the severity of lower-limb disability, fatigue, mood disorders, other problems related to MS, and upper-limb disability. Of all the symptoms, lower-limb disability, fatigue, and mood disorders had the strongest relation with adaptation. All of the analysed symptoms were found to correlate with HRQoL. Of all the symptoms, HRQoL was most affected by lower- and upper-limb disability, fatigue, other MS problems, and mood disorders.

Relating health-related Quality of Life to disability progression in multiple sclerosis, using the 5-level EQ-5D

2013 ◽  
Vol 19 (9) ◽  
pp. 1190-1196 ◽  
Author(s):  
Emer Fogarty ◽  
Cathal Walsh ◽  
Roisin Adams ◽  
Christopher McGuigan ◽  
Michael Barry ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Resource Allocation ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Anxiety Depression ◽  
The Relationship ◽  
Inform Resource Allocation

Background: Increasing use of the Quality-Adjusted Life-Year to inform resource allocation decision-making has highlighted the importance of relating clinical and health-related quality of life (HRQoL) outcomes in multiple sclerosis (MS) patients. Objective and Methods: To investigate the relationship between the Expanded Disability Status Scale (EDSS) and HRQoL utility, using the 5-level EQ-5D (EQ-5D-5L). The discriminatory power of the EQ-5D-5L was assessed using Shannon’s indices. Results: A linear decline in utility was observed with changes in EDSS score from 0 to 6, after which point the relationship exhibited greater variability. Mean utility values ranged from −0.22 at EDSS 9 to 0.88 at EDSS 0. We found that the discriminative capacity of the EQ-5D-5L was considerably lower for the domains self-care and anxiety/depression, compared with other health-related domains. Conclusion: In its first reported use in an MS population, the EQ-5D-5L displayed good discriminatory capacity, although performance differed between the various domains of health, with evidence of a ceiling effect present in the domains of self-care and anxiety/depression. The EQ-5D-5L demonstrated a high correlation with EDSS in our MS cohort up to EDSS 6, after which point the utility valuation of severe health states exhibited much greater variability. Utility estimates from this study may be used in economic evaluations of disease-modifying therapies in MS, to inform resource-allocation decisions.

scholarly journals Depression mediates the relationship between fatigue and mental health-related quality of life in multiple sclerosis

2021 ◽  
Vol 47 ◽  
pp. 102620
Author(s):  
Alexander Fidao ◽  
Alysha De Livera ◽  
Nupur Nag ◽  
Sandra Neate ◽  
George A Jelinek ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Multiple Sclerosis ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

scholarly journals The Relationships between Physical Activity, Self-Efficacy, and Quality of Life in People with Multiple Sclerosis

2019 ◽  
Vol 9 (12) ◽  
pp. 121 ◽  
Author(s):  
Marco Guicciardi ◽  
Maria Carta ◽  
Massimiliano Pau ◽  
Eleonora Cocco
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Multiple Sclerosis ◽  
Goal Setting ◽  
Self Efficacy ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Relationship

Regular physical activity (PA) can enhance the physical and mental health of people with Multiple Sclerosis (MS) because of its impact on muscular strength, mobility, balance, walking, fatigue, pain and health-related quality of life (HRQoL). Previous studies have hypothesized that the relationship between PA and HRQoL is mediated by self-efficacy. The aim of this research is to evaluate whether self-efficacy in goal setting and self-efficacy in the management of symptoms, mediate the relationship between PA and HRQoL, in a similar way to exercise self-efficacy. A sample of 28 participants with MS (18 females) and different levels of physical activity have been recruited and completed the following measures: (a) physical activity (GLTEQ); (b) health-related quality of life (SF-12); (c) self-efficacy in the management of Multiple Sclerosis (SEMS) and, (d) exercise self-efficacy (EXSE). The statistical analysis highlighted that self-efficacy in goal setting mediated the relationship between PA and mental health better than exercise self-efficacy. Our findings suggest that self-efficacy in goal setting can contribute to the adoption and maintenance of regular physical activity for long-lasting times, supporting and increasing the mental quality of life of people suffering from MS.

scholarly journals Fatigue, Physical Disability and Self-Efficacy as Predictors of the Acceptance of Illness and Health-Related Quality of Life in Patients with Multiple Sclerosis

2021 ◽  
Vol 18 (24) ◽  
pp. 13237
Author(s):  
Joanna Dymecka ◽  
Rafał Gerymski ◽  
Rafał Tataruch ◽  
Mariola Bidzan
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Self Efficacy ◽  
Neurological Symptoms ◽  
Health Related Quality ◽  
Permanent Disability ◽  
Related Quality ◽  
Health Related ◽  
Acceptance Of Illness

Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central nervous system that leads to permanent disability and many neurological symptoms, making everyday functioning difficult. The predictors of the acceptance of illness and the health-related quality of life in people with MS include the degree of disability, neurological symptoms and psychosocial factors, such as personal resources. The aim of our study is to determine the relationships among disability, fatigue, self-efficacy, acceptance of illness and quality of life. The study group consisted of 137 people diagnosed with multiple sclerosis—73 women and 64 men. EDSS, GNDS, LSES, AIS and MSIS-29 were used in the present study. The results show that all tested variables were significantly correlated with each other. Disability and fatigue were significant predictors of both the physical and psychological aspects of patients’ quality of life. Self-efficacy was a significant predictor of both the acceptance of illness and the psychological aspect of patients’ quality of life. Based on the current research study, it can be concluded that factors of a biomedical nature explain other aspects of struggling with the disease, rather than psychological resources.

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