Efficacy of Palonosetron and Dexamethasone for Prevention of Post-operative Nausea and Vomiting in Female Patients Undergoing Laparoscopic Cholecystectomy: A Prospective Randomised Double-Blind Trial

2021 ◽  
Vol 49 (5) ◽  
pp. 400-406
Author(s):  
Mohd Atesham Khan ◽  
◽  
Anju Gupta ◽  
Nishkarsh Gupta ◽  
Manasij Mitra ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Nausea And Vomiting ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Female Patients ◽  
Post Operative Nausea

scholarly journals A prospective, randomized, double-blind trial to compare body weight-adjusted and fixed doses of palonosetron for preventing postoperative nausea and vomiting in obese female patients

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227490
Author(s):  
Nathalia Gouveia de Araujo Ferreira ◽  
Ismar Lima Cavalcanti ◽  
Alexandra Rezende Assad ◽  
Louis Barrucand ◽  
Estêvão Luiz Carvalho Braga ◽  
...  
Keyword(s):  
Body Weight ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Female Patients ◽  
Obese Female

scholarly journals Evaluating the Effect of Intraoperative Dextrose 10% Administration on Reducing Postoperative Nausea and Vomiting after Laparoscopic Surgery

2019 ◽  
Vol 13 (1) ◽  
pp. 78-85
Author(s):  
Ashraf Nabil Saleh ◽  
Dalia Fahmy Emam ◽  
Mohamed Mohamed Kamal
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Study Groups ◽  
Primary Objective ◽  
Nausea And Vomiting ◽  
Controlled Study ◽  
Double Blind ◽  
Female Patients ◽  
Medication Consumption

Background: Although PONV is usually self-limiting or is treated without sequelae, the incidence of PONV could be as high as 70% to 80% in high-risk populations such as female sex, obese patients, age younger than 40 years, nonsmoker patients, history of PONV or motion sickness. Objectives: The study aimed to investigate whether dextrose 10% decreases the incidence of postoperative nausea and vomiting in female patients undergoing laparoscopic cholecystectomy Materials and Methods: This prospective, double-blind randomized placebo-controlled study comprised 130 ASA physical status I and II nonsmoker female patients, 20-40 years of age, scheduled for laparoscopic cholecystectomy at Ain Sham University – Assembled operating theater from August 2018 to October 2018. Patients were arbitrarily divided into two study groups of 65 patients each. Group LR received lactated Ringer’s solution and group D received 10% dextrose. The primary objective of this study was to compare the incidence of PONV in the study treatment groups. The secondary outcomes included measurement of antiemetic medication consumption as well as blood glucose changes between groups. Results: 50 from a total of 65 participants (76.9%) in Lactated Ringer (LR) group experienced nausea. On the other hand, 30 participants only (46.2%) in dextrose (D) group were nauseated. This dissimilarity was statistically highly significant (P= 0.0003). Conclusion: In this study, dextrose 10% administration resulted in improved postoperative emesis management as explained by the lower incidence of nausea and rescue antiemetic consumption.

scholarly journals Piritramide—A New Long-acting Analgesic

1973 ◽  
Vol 1 (4) ◽  
pp. 308-314 ◽  
Author(s):  
David B. Gibb ◽  
Nicholas Pikler
Keyword(s):  
Nausea And Vomiting ◽  
Double Blind Trial ◽  
Double Blind ◽  
Duration Of Action ◽  
Blind Trial ◽  
Long Acting

Piritramide is a synthetic analgesic of the piperidine group. Reports indicate that it is a potent, long-acting drug and that the incidence of nausea and vomiting following its administration is very low. In this series of 60 cases piritramide 15 mg was compared with morphine 10 mg in a double-blind trial. The drug was found to have a potency similar to that of morphine and a mean duration of action of greater than 6½ hours (morphine 4 ½ hours). The incidence of nausea and vomiting was low with both drugs and piritramide appeared to exert a slight anti-emetic effect.

Short-term outcomes of single-site robotic cholecystectomy versus four-port laparoscopic cholecystectomy: a prospective, randomized, double-blind trial

2015 ◽  
Vol 30 (7) ◽  
pp. 3089-3097 ◽  
Author(s):  
Andrea Pietrabissa ◽  
Luigi Pugliese ◽  
Alessio Vinci ◽  
Andrea Peri ◽  
Francesco Paolo Tinozzi ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Single Site ◽  
Double Blind Trial ◽  
Short Term ◽  
Double Blind ◽  
Blind Trial ◽  
Robotic Cholecystectomy
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