scholarly journals THE Assesssment of PARAMETERS OF LONG-TERM METABOLIC control in children WITH DIABETES TYPE I using UNDERGOING different types of insulin THerapy and using different means of its introduction

2015 ◽  
pp. 41-45
Author(s):  
N. V. Volkova ◽  
H. G. Mikhno ◽  
A. V. Solntseva
Keyword(s):  
Glycosylated Hemoglobin ◽  
Diabetes Type ◽  
Type I ◽  
Diabetes Type 1 ◽  
Complications Of Diabetes ◽  
Acute Complications ◽  
Different Types ◽  
Diabetes Type I

Objective: to carry out comparative analysis of long-term compensation of carbohydrate metabolism in children with diabetes type 1 undergoing different types of insulin therapy and using different means of its introduction. Material and methods . We analyzed data of 77 medical histories of children with diabetes type 1. The patients were divided into 3 groups depending on the type of insulin and the way of its introduction. We analyzed both initial and current for the moment of the experiment parameters of glycosylated hemoglobin levels, frequency of blood glucose self-testing, presence of acute complications of diabetes mellitus. Results . The children undergoing continuous subcutaneous insulin introduction revealed significant decrease of glycosylated hemoglobin levels and absence of acute complications of diabetes. The group of children using insulin analogues for a long time had significantly lower glycemia variability and revealed no acute complications of diabetes. Conclusions . We revealed long-term compensation of carbohydrate metabolism in the children with diabetes type I who used insulin pump therapy.

Multi-collector ICP-mass spectrometry reveals changes in the serum Mg isotopic composition in diabetes type I patients

2019 ◽  
Vol 34 (7) ◽  
pp. 1514-1521 ◽  
Author(s):  
Rosa Grigoryan ◽  
Marta Costas-Rodríguez ◽  
Steven Van Laecke ◽  
Marijn Speeckaert ◽  
Bruno Lapauw ◽  
...  
Keyword(s):  
Isotopic Composition ◽  
Reference Population ◽  
Diabetes Type ◽  
Type I ◽  
Diabetes Type 1 ◽  
Age And Gender ◽  
Diabetes Type I ◽  
And Gender ◽  
Icp Mass Spectrometry

Serum Mg shows a lighter isotopic composition in diabetes type-1 patients than in an age- and gender-matched reference population.

Overestimation of Risk and Increased Fear of Long-term Complications of Diabetes in People with Type 1 and 2 Diabetes

2019 ◽  
Vol 127 (10) ◽  
pp. 645-652 ◽  
Author(s):  
Florian Arend ◽  
Ulrich A. Müller ◽  
Andreas Schmitt ◽  
Margarete Voigt ◽  
Nadine Kuniss
Keyword(s):  
Diabetes Complications ◽  
Metabolic Diseases ◽  
Population Based ◽  
Diabetes Type ◽  
Complications Of Diabetes ◽  
Personal Risk ◽  
Disease Management Programmes

AbstrAct Objective The quality report of the disease management programmes of North Rhine Westphalia 2016 showed prevalences for long-term complications (neuropathy, nephropathy, retinopathy) of less than 30% for people with diabetes type 1 (DM1) and type 2 (DM2). The aim of this study was to assess risk expectations and fear regarding long-term complications of diabetes in people with DM1 and DM2. Methods We assessed risk expectations and fear regarding diabetes complications in people with DM1 (n=110) and DM2 (n=143 without insulin, n=249 with insulin) visiting an University outpatient department of metabolic diseases. Fear of long-term complications was measured with the “Fear of Complications Questionnaire (FCQ)” (range 0–45 points, scores ≥30 suggest elevated fear). Participants were asked to estimate general and personal risks of long-term complications 10 years after developing diabetes in %. Results Elevated fear of complications (FCQ scores ≥30) was observed in 34.5, 25.9, and 43.0% of those with DM1, DM2 without insulin and DM2 with insulin, respectively. Participants estimated a mean general risk of diabetes-related complications after 10 years amounting to 45.9±15.8% (DM1), 49.7±15.4% (DM2 without insulin), and 52.5±16.4% (DM2 with insulin) and personal risk with 52.5±24.4% (DM1), 45.8±22.7% (DM2 without insulin), and 54.1±23.4% (DM2 with insulin), respectively. Higher risk expectations were associated with higher fear of complications (p<0.001). Conclusion Risk estimations regarding long-term complications were exaggerated in people with DM1 and DM2. About one third of the participants reported elevated fear of complications. Participants’ risk expectations and fear regarding diabetes complications appear excessive compared to population-based prevalence rates.

Exceptional case of disseminated necrobiosis lipoidica similar to a sarcoidosis form at the child affected by diabetes type I

2016 ◽  
Vol 19 (4) ◽  
pp. 227-230
Author(s):  
V. T Bazaev ◽  
M. B Tseboeva ◽  
M. S Tsarueva
Keyword(s):  
Diabetes Mellitus ◽  
Short Review ◽  
Exceptional Case ◽  
Diabetes Type ◽  
Type I ◽  
Necrobiosis Lipoidica ◽  
Modern Methods ◽  
Diabetes Type I ◽  
Methods Of Treatment

The article describes the infrequent disseminated necrobiosis lipoidica similar to a sarcoidosis form which developed at the five-year-old child affected by type 1 diabetes mellitus. The short review concerns the questions of an etiology, pathogenesis, clinical forms, diagnostics and the modern methods of treatment of the described pathology. In the review 26 sources of literature are used. The case is of interest to dermatovenereologists, endocrinologists, pediatricians.

Continuous Glucose Monitoring for Glycemic Control in Children and Adolescents Diagnosed with Diabetes Type 1: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Elena Dorando ◽  
Thomas Haak ◽  
Dawid Pieper
Keyword(s):  
Systematic Review ◽  
Glycemic Control ◽  
Children And Adolescents ◽  
Meta Analysis ◽  
Glucose Monitoring ◽  
Diabetes Type ◽  
Diabetes Type 1 ◽  
Meta Analyses

Abstract Aim The aim of this meta-analysis was to evaluate the impact of continuous glucose monitoring (CGM) systems on short- and long-term glycemic control in children and adolescents diagnosed with diabetes type 1. Methods The review was registered in PROSPERO (CRD42019135152). We partly updated a formerly published systematic review and searched several databases (Ovid MEDLINE, Embase, CENTRAL, and Clinicaltrials.gov) in May 2019. Summary measures were estimated as relative risks (RR) and standardized mean differences (SMD). The primary endpoint of our analysis was frequency of hypoglycemic events. Quality of evidence was evaluated using the GRADE approach. Results Eleven studies with a total number of 818 patients were included in our review. Meta-analyses indicated a potential benefit of CGM systems regarding the relative risk of a severe hypoglycemic event (RR 0.78; 95% CI 0.29 to 2.04) and mean level of HbA1c at end of study (SMD -0.23; 95% CI -0.46 to 0.00). Certainty of evidence for effect estimates of these meta-analyses was low due to risk of selection bias and imprecision of the included studies. Qualitative analyses of the secondary outcomes of user satisfaction and long-term development of blood glucose supported these findings. Conclusion CGM systems may improve glycemic control in children and adolescents diagnosed with diabetes type 1, but the imprecision of effects is still a problem. Only a few studies examined and reported data for pediatric populations in sufficient detail. Further research is needed to clarify advantages and disadvantages of CGM systems in children and adolescents.

Reduced iron parameters and cognitive processes in children and adolescents with DM1 compared to those with standard parameters

2016 ◽  
Vol 64 (3) ◽  
pp. 782-785 ◽  
Author(s):  
Ewa Mojs ◽  
Maia Stanisławska–Kubiak ◽  
Rafał W Wójciak ◽  
Julita Wojciechowska ◽  
Sabina Przewoźniak
Keyword(s):  
Children And Adolescents ◽  
Glycosylated Hemoglobin ◽  
Blood Parameters ◽  
Diabetes Type ◽  
Mean Corpuscular Hemoglobin ◽  
Diabetes Type 1 ◽  
Flame Atomic Absorption ◽  
Patients With Diabetes ◽  
Iron Parameters

Anemia in patients with diabetes is not scarce and may contribute to the complications of the disease. The risk of iron deficiency parameters in child sufferers of diabetes type 1, observed in studies, can lead to cognitive impairment. The aim of the study was to determine whether children and adolescents with diabetes type 1, in whom reduced ferric parameters are observed in control tests, may also show reduced cognitive performance. The study included 100 children with diabetes type 1 at the age of 6–17 years. During control tests, patients’ morphological blood parameters were measured: red blood cells (RBC), hemoglobin, glycosylated hemoglobin, hematocrit, RBC volume, the molar mass of hemoglobin in RBC (MCH), mean corpuscular hemoglobin in RBC and iron concentrations in serum using flame atomic absorption spectroscopy and the Wechsler Intelligence Scale for Children (WISC-R). Results in the group of children with a diabetes type 1 significantly lower concentration of three ferric parameters affect the non-verbal intelligence measured with WISC-R. The prevalence of reduced ferric parameters justifies further screening in all children with diabetes type 1 and taking up appropriate preventive measures to reduce the risk of their occurrence.

scholarly journals Glycemic Variability in Type 1 Diabetes—Does It Matter?

2014 ◽  
Vol 10 (01) ◽  
pp. 20 ◽  
Author(s):  
Frank L Schwartz ◽  
Cynthia R Marling ◽  
◽  
Keyword(s):  
Type 1 Diabetes ◽  
Clinical Assessment ◽  
Predictive Power ◽  
Glycosylated Hemoglobin ◽  
Glycemic Variability ◽  
Complications Of Diabetes ◽  
Patients With Diabetes ◽  
Clinical Research Trials

Clinical assessment of glycemic variability (GV) attempts to measure factors that may be contribute to tissue damage and the complications of diabetes that are not measured in glycosylated hemoglobin (HbA1C). Physicians managing patients with diabetes immediately understand the concept of GV; however, how it is assessed in clinical research trials and whether it has any predictive power in patients with type 1 diabetes is controversial and uncertain. This review is intended to help the reader understand the various GV metrics currently being reported in the literature, the potential mechanisms by which GV may contribute to the pathogenesis of the long-term complications of diabetes, and, finally, the evidence that reducing GV is beneficial to patients with type 1 diabetes.

Pediatric Self-Efficacy for Diabetes-Type-1 Scale--German Version

2020 ◽  
Author(s):  
Dominik Sethe ◽  
Arndt Büssing ◽  
Dörte Hilgard ◽  
Bettina Berger
Keyword(s):  
Self Efficacy ◽  
Diabetes Type ◽  
Diabetes Type 1 ◽  
German Version
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