scholarly journals Vulvar Lichen Sclerosus in Female Patients with Localized Scleroderma

2019 ◽  
pp. 101-107
Author(s):  
L. A. Poroshina ◽  
E. I. Rublevskaya ◽  
S. L. Achinovich
Keyword(s):  
Clinical Manifestations ◽  
Lichen Sclerosus ◽  
Diagnosis And Treatment ◽  
Localized Scleroderma ◽  
Female Patients ◽  
Vulvar Lichen Sclerosus ◽  
Clinical Cases

The article presents up-to-date literary data on the etiopathogenesis, prevalence of lichen sclerosus, defines the clinical manifestations and classification of the disease, and considers the issues of its diagnosis and treatment. The article also describes 3 clinical cases of genital lesions in female patients with localized scleroderma. In our opinion, lichen sclerosus is one of the forms of localized scleroderma.

Scleroderma and Related Disorders

2017 ◽  
Author(s):  
Kristine Phillips
Keyword(s):  
Differential Diagnosis ◽  
Antinuclear Antibodies ◽  
Clinical Course ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Localized Scleroderma ◽  
Eosinophilic Fasciitis ◽  
Tomographic Images ◽  
Computed Tomographic

Scleroderma spectrum diseases are a heterogeneous group of disorders that are distinguished by abnormalities of the connective tissue in the skin and, in some cases, other organs. Each disorder may be characterized by the extent of cutaneous and internal involvement, as well as histopathologic features of skin biopsy. Scleroderma spectrum diseases include systemic scleroderma, localized scleroderma, and eosinophilic fasciitis. This chapter reviews the classification, epidemiology, etiology, pathophysiology and pathogenesis, diagnosis, differential diagnosis, treatment, outcome measures, management, and clinical course of scleroderma as well as the definition and classification, etiology/genetics, differential diagnosis, and treatment of localized scleroderma. Also discussed are the definition and classification, epidemiology, etiology/genetics/pathogenesis, diagnosis, differential diagnosis, and treatment of eosinophilic fasciitis. Tables review the classification of—and antinuclear antibodies in—scleroderma as well as the key assessments and interventions in scleroderma management. Figures illustrate the disease's presentation and clinical manifestations, including several images of scleroderma of the hands; face, palmar, and buccal telangiectasias in a patient with scleroderma; a radiograph demonstrating calcinosis of the elbow; Raynaud’s phenomenon; high-resolution computed tomographic images of diffuse cutaneous scleroderma, scleroderma and severe pulmonary hypertension, and limited cutaneous scleroderma; plus an esophagram demonstrating hypomotility. This review contains 11 highly rendered figures, 3 tables, and 72 references.

Scleroderma and Related Disorders

2017 ◽  
Author(s):  
Kristine Phillips
Keyword(s):  
Differential Diagnosis ◽  
Antinuclear Antibodies ◽  
Clinical Course ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Localized Scleroderma ◽  
Eosinophilic Fasciitis ◽  
Tomographic Images ◽  
Computed Tomographic

Scleroderma spectrum diseases are a heterogeneous group of disorders that are distinguished by abnormalities of the connective tissue in the skin and, in some cases, other organs. Each disorder may be characterized by the extent of cutaneous and internal involvement, as well as histopathologic features of skin biopsy. Scleroderma spectrum diseases include systemic scleroderma, localized scleroderma, and eosinophilic fasciitis. This chapter reviews the classification, epidemiology, etiology, pathophysiology and pathogenesis, diagnosis, differential diagnosis, treatment, outcome measures, management, and clinical course of scleroderma as well as the definition and classification, etiology/genetics, differential diagnosis, and treatment of localized scleroderma. Also discussed are the definition and classification, epidemiology, etiology/genetics/pathogenesis, diagnosis, differential diagnosis, and treatment of eosinophilic fasciitis. Tables review the classification of—and antinuclear antibodies in—scleroderma as well as the key assessments and interventions in scleroderma management. Figures illustrate the disease's presentation and clinical manifestations, including several images of scleroderma of the hands; face, palmar, and buccal telangiectasias in a patient with scleroderma; a radiograph demonstrating calcinosis of the elbow; Raynaud’s phenomenon; high-resolution computed tomographic images of diffuse cutaneous scleroderma, scleroderma and severe pulmonary hypertension, and limited cutaneous scleroderma; plus an esophagram demonstrating hypomotility. This review contains 11 highly rendered figures, 3 tables, and 72 references.

Scleroderma and Related Disorders

2018 ◽  
Author(s):  
Kristine Phillips
Keyword(s):  
Differential Diagnosis ◽  
Antinuclear Antibodies ◽  
Clinical Course ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Localized Scleroderma ◽  
Eosinophilic Fasciitis ◽  
Tomographic Images ◽  
Computed Tomographic

Scleroderma spectrum diseases are a heterogeneous group of disorders that are distinguished by abnormalities of the connective tissue in the skin and, in some cases, other organs. Each disorder may be characterized by the extent of cutaneous and internal involvement, as well as histopathologic features of skin biopsy. Scleroderma spectrum diseases include systemic scleroderma, localized scleroderma, and eosinophilic fasciitis. This chapter reviews the classification, epidemiology, etiology, pathophysiology and pathogenesis, diagnosis, differential diagnosis, treatment, outcome measures, management, and clinical course of scleroderma as well as the definition and classification, etiology/genetics, differential diagnosis, and treatment of localized scleroderma. Also discussed are the definition and classification, epidemiology, etiology/genetics/pathogenesis, diagnosis, differential diagnosis, and treatment of eosinophilic fasciitis. Tables review the classification of—and antinuclear antibodies in—scleroderma as well as the key assessments and interventions in scleroderma management. Figures illustrate the disease's presentation and clinical manifestations, including several images of scleroderma of the hands; face, palmar, and buccal telangiectasias in a patient with scleroderma; a radiograph demonstrating calcinosis of the elbow; Raynaud’s phenomenon; high-resolution computed tomographic images of diffuse cutaneous scleroderma, scleroderma and severe pulmonary hypertension, and limited cutaneous scleroderma; plus an esophagram demonstrating hypomotility. This review contains 11 highly rendered figures, 3 tables, and 72 references.

scholarly journals LICHEN SCLEROSUS OF THE VULVA IN PATIENTS WITH LIMITED SCLERODERMA

2020 ◽  
Vol 3 (13) ◽  
pp. 45-52
Author(s):  
T.F. Tatarchuk ◽  
T.V. Protsenko ◽  
V.V. Dunaevskaya
Keyword(s):  
Secondary Infection ◽  
Clinical Manifestations ◽  
Practical Interest ◽  
Calcineurin Inhibitors ◽  
Lichen Sclerosus ◽  
Diagnosis And Treatment ◽  
Infrared Range ◽  
Fluid Loss ◽  
Limited Scleroderma ◽  
Clinical Cases

Modern literature information on the etiopathogenetic prevalence of lichen sclerosus has been presented by the authors; clinical manifestations and classification of the disease have been outlined; diagnosis and treatment issues have been discussed in the article. 3 clinical cases of genital lesions in the form of lichen sclerosus in patients with limited scleroderma have been described. In our opinion, lichen sclerosus is one of the forms of limited scleroderma. Purpose. To investigate the conditions for the diagnosis and treatment of genital lesions in the form of lichen sclerosus in patients with limited scleroderma. Methods. The first line of therapy for lichen sclerosus is the use of super-powerful topical glucocorticoids. Clobetasol propionate 0.05% is to be used for 3 months (1 month daily, then every other day for a month, then 2 times a week for a month). After 3 months of treatment, if a positive effect is declared, maintenance therapy is recommended once a week. Topical calcineurin inhibitors are recommended as a second-line therapy. Effective and safe excipients are emollients that moisturize the skin and mucous membranes, prevent transdermal fluid loss, and reduce subclinical inflammation. The possibility of using triamcinolone (1-2 mg) onto pathologically altered tissue in women with lichen sclerosus where there are hyperkeratotic sites resistant to GCS can be considered after exclusion of intraepithelial neoplasia or malignant transformation. The effectiveness of physiotherapeutic methods, such as low-intensity helium-neon laser radiation in the red or infrared range, treatment with sunlight and radiation generated by medical equipment, photodynamic therapy has been described. Results. One of the important measures is the elimination of irritating factors, as well as careful care of the vulva and the treatment of secondary infection. It consists in adherence to a diet (exclusion of spicy, salty, sweet foods, caffeine-containing products, alcohol) and intimate hygiene rules (limitation / exclusion of soap-containing products, deodorants, synthetic underwear, pads, tampons). The underwear should not be very tight. In addition, patients should exclude mechanical irritation of the affected area, including shaving. With extreme manifestation of itching, it is recommended to prescribe desensitizing therapy and sedatives. Conclusions. Clinical cases of practical interest in connection with the clinical manifestations of limited scleroderma on the skin and genitals have been considered. Frequent lesions of the genital organs in the form of a typical clinic of lichen sclerosus in women suffering from limited scleroderma, the similarity of their clinic, histological picture and pathogenesis have been noted. All this gives a reason to consider lichen sclerosus as a manifestation of limited scleroderma.

scholarly journals 310 A new proposal for the clinical classification of vulvar lichen sclerosus: an observational prospective study

2020 ◽  
Author(s):  
Veronica Boero ◽  
Carlo A Liverani ◽  
Massimiliano Brambilla ◽  
Ermelinda Monti ◽  
Filippo Murina ◽  
...  
Keyword(s):  
Prospective Study ◽  
Lichen Sclerosus ◽  
Clinical Classification ◽  
Observational Prospective Study ◽  
Vulvar Lichen Sclerosus

scholarly journals OBSTETRICAL HEMATOMAS (clinical lecture, part I)

2016 ◽  
pp. 4-9
Author(s):  
O. A. Teslova
Keyword(s):  
Health Status ◽  
Soft Tissues ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Birth Canal ◽  
The Third ◽  
Maternity Hospitals ◽  
Clinical Lecture ◽  
Clinical Cases

The clinical lecture deals with topical emergency problem in obstetrical practice, i.e. hematomas of soft tissues of the birth canal. The first part of the lecture presents modern data on the epidemiology and etiopathogenesis, classification approaches, clinical manifestations, modern facilities for diagnosis and treatment of obstetrical hematomas of different localization. The second part of the lecture will describe and analyze clinical cases of hematomas of the birth canal that occurred at maternity hospitals of Gomel region, as well as rare cases of obstetric hematomas according to foreign publications. The third part of the lecture will present data on health status of children whose mothers developed obstetrical hematomas during their delivery.

A Comprehensive Review on Classification of Oral Ulcerative Lesions

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Hina Handa
Keyword(s):  
Oral Cavity ◽  
Soft Tissues ◽  
Clinical Manifestations ◽  
Diagnosis And Treatment ◽  
Diagnostic Skills ◽  
Oral Mucosal Lesions ◽  
Treatment Plans ◽  
Common Group ◽  
Ulcerative Lesions

Oral mucosal lesions are a broad group of lesions which are located in the soft tissues of the oral cavity identified by its specific etiology, clinical manifestations, differential diagnosis and treatment. White lesions of the oral cavity constitute a rather common group of lesions that are encountered during routine clinical dental practice. The process of clinical diagnosis and treatment planning is of great concern to the patient as it determines the prognosis. There should be in-depth knowledge to the consultant about the varied clinical features, etiology of the disease and various treatment plans. Clinical diagnostic skills and ideal judgment forms the key to successful management of white lesions of the oral cavity This review will discuss many of the most common intraoral white lesions including their clinical presentation, how to make an accurate diagnosis

scholarly journals Hereditary Dental Diseases – Clinical Diagnosis and Strategies for Treatment and Rehabilitation

2020 ◽  
Vol 8 (F) ◽  
pp. 293-303
Author(s):  
Susanna Sergeevna Sologova ◽  
Aidan Elchin kizi Rzaeva ◽  
Olga Ivanovna Tereshkina ◽  
Diana Igorevna Sologova ◽  
Natalia Nikolaevna Vlasova ◽  
...  
Keyword(s):  
Treatment Strategies ◽  
Relevant Information ◽  
Diagnosis And Treatment ◽  
Systematic Analysis ◽  
Treatment And Prevention ◽  
Prevention And Treatment ◽  
Dental Diseases ◽  
And Cluster Analysis ◽  
Clinical Cases

AIM: The research has been aimed at optimization of approaches to diagnosis, prevention, and treatment strategies to the hereditary dental diseases based on the analysis of modern relevant information. METHODS: Using the methods of content analysis and cluster analysis, the information included in periodicals, as well as educational and non-regulatory publications for the period of 2011–2019, was systematized and structured; the analysis of sources devoted to modern approaches to the diagnosis, prevention, and treatment of hereditary dental diseases, their genetic etiology, with the description of clinical cases and illustrations for each example, was conducted; hereditary dental diseases were classified; based on a comparative analysis, approaches to the diagnosis, treatment, and prevention of these diseases were optimized. RESULTS: The most significant hereditary dental diseases have been identified, the classification of approaches to their diagnosis and treatment has been presented, the scheme of drug therapy has been optimized depending on the pathology. CONCLUSION: The systematic analysis of information on hereditary dental diseases with the description of clinical cases for each nosology has been carried out for the 1st time, and the approaches to their diagnosis and treatment have been optimized with due consideration of domestic and foreign experience.

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