scholarly journals Constanza Romero on August Wilson's Legacy: Past, Present, and Future

2019 ◽  
Vol 1 ◽  
Author(s):  
Sandra G. Shannon

The following interview occurred on Tuesday, December 4, 2018 at 5:00 p.m. EST (2:00 p.m. PST).  Dr. Sandra Shannon, Professor Emerita, Howard University, conducted the interview from Washington, DC, on behalf of the Journal.  Constanza Romero, Director of the August Wilson Estate and August Wilson's widow, spoke from Seattle, Washington.

1998 ◽  
Vol 72 (3-4) ◽  
pp. 297-304
Author(s):  
Bill Maurer

[First paragraph]We Paid Our Dues: Women Trade Union Leaders of the Caribbean. A. LYNN BOLLES. Washington DC: Howard University Press, 1996. xxxviii + 250 pp. (Paper US$21.95)Gender: A Caribbean Multi-Disciplinary Perspective. ELSA LEO-RHYNIE, BARBARA BAILEY & CHRISTINE BARROW (eds.). Kingston: Ian Randle, 1997. xix + 358 pp. (Paper n.p.)Daughters of Caliban: Caribbean Women in the Twentieth Century. CONSUELO LOPEZ SPRINGFIELD (ed.). Bloomington: Indiana University Press, 1997. xxi + 316 pp. (Cloth US$ 35.00, Paper US$ 17.95)Two weeks before I began writing this review essay, I had the misfortune to contract food poisoning while visiting New York. I was admitted to St. Vincent's Hospital in Greenwich Village where I found myself under the capable care of a team of West Indian nurses. At the time, I didn't give this much thought; I was simply happy to be getting good care far from home. The day before I was released, my right arm swelled up from the intravenous drip that had been delivering fluids and antibiotics into my body. It was first noticed by one of the Jamaican nurses, who told me that the IV had "infiltrated" my arm and that, as a result, my "fluids were out of balance," and this was keeping me from getting well. She promptly pointed this out to another nurse, who took out the IV and stuck another one into my left arm.


2005 ◽  
Vol 5 (4) ◽  
pp. 1850076
Author(s):  
Kwame Bawuah-Edusei

An African commentary on the Doha Development Round. Kwame Bawuah-Edusei is Ambassador of Ghana to Switzerland and Austria and Permanent Representative of Ghana to the UN offices and international organizations in Geneva, including the WTO. He obtained his MD degree in 1982 at the University of Science and Technology, School of Medical Sciences, Kumasi Ghana, worked in Ghana for two years, and later studied in the United States. He specialized in Family Medicine at Howard University Hospital, Washington DC, and worked as a physician for the Dewitt Army Hospital in Fort Belvoir, Virginia. He subsequently practiced at Educe Medical Center in Alexandria, Virginia. During this period he was active in promoting business in his native Ghana and extensively involved in humanitarian work in the deprived Northern part of his country. He became a community leader in North America and was instrumental in institutionalizing democracy in Ghana. He became a Director of the EO group, an energy Company, and President of Educe Incorporated in Ghana.


2022 ◽  
pp. 000313482110679
Author(s):  
Don K. Nakayama

The tens of thousands of enslaved Blacks liberated by union forces during the American Civil War were considered seized property and thus were referred to as contraband. As wartime refugees they sought protection in federal military installations, popularly known as contraband camps, located throughout the occupied South. One of the largest was Camp Baker in the rural northwestern sector of Washington, DC, where about 40,000 persons were sheltered. To provide basic medical care, the military outfitted, in 1863, an infirmary called the Contraband Hospital, later renamed Freedmen’s Hospital. From its founding in 1867 the medical department of Howard University was attached to Freemen’s Hospital, which in 1975 was renamed the Howard University Hospital, the two institutions establishing a long partnership of medical education and hospital care that continues to the present day.


Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Navya Lakkappa ◽  
Clara Berdasco ◽  
Catalin Filipeanu ◽  
Eric D Lazartigues

UBR1 and BRCC36 regulate ACE2 Ubiquitination and Deubiquitination in Ang-II induced Hypertension. Navya Lakkappa 1 , Clara Berdasco 1 , Catalin Filipeanu 2 , Eric Lazartigues 1 1. Pharmacology, LSUHSC, New Orleans, LA; 2. Pharmacology, Howard University, Washington, DC. ACE2 is undergoing Ang-II-mediated internalization, ubiquitination and degradation, contributing to hypertension. Using proteomics and bioinformatic analysis, we identified UBR1 and BRCC36 and evaluated their role in ACE2 ubiquitination in hypertension. Following gonadectomy, blood pressure (BP, telemetry) was recorded in C57BL6/J mice (3-month-old, n=10/group) infused with Ang-II (490 ng/Kg/min/4 weeks sc). UBR1, BRCC36 and ACE2 expression was assessed in heart and kidneys (capillary western). Ang-II infusion induced a significant mean BP increase in all groups (sham males: 133 ±0.6; castrated: 141 ±0.6; sham females: 134 ±0.7; ovariectomized: 130 ±0.3 mmHg; n=6, one-way ANOVA, P<0.001). UBR1 levels were similar between sexes while cardiac BRCC36 was 2-fold higher in females (P<0.001). Ang-II-mediated hypertension led to a 4-fold increase in UBR1 in males heart and kidneys (P<0.001) and a 2-fold increase in females (P<0.01) while gonadectomy blunted this effect by 50%. Castration did not affect BRCC36 levels while ovariectomy reduced them by 5-fold. Males infused with Ang-II showed no significant change in BRCC36 expression while hypertensive females had a dramatic reduction (5-fold, P<0.001) in the heart. Overall, UBR1 was associated with a reduction and BRCC36 was associated with an increase of ACE2 levels. Endothelial cells (HAEC) exposed to Ang-II (100 nM for 4h) had a 2-fold increase in UBR1 and a 10-fold reduction in ACE2 (n=3: one-way ANOVA, P< 0.01). Complete knockdown of UBR1 resulted in a 10-fold increase in ACE2 levels (n=3: one-way ANOVA, P<0.05). In HEK293T cells transfection with BRCC36 reversed the Ang-II effects (72533.5 ±4432.2 vs. 42204.2 ±4338.7; FU/min/μg protein, n=3, one-way ANOVA, P<0.05). Together, we show that ACE2 expression in hypertension is differentially regulated by URB1 and BRCC36 and depends on sex hormones. Inhibition of UBR1 and upregulation of BRCC36 could be a new therapeutic strategy to prevent ACE2 ubiquitination in hypertension.


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