scholarly journals Prevalence of Diabetes Mellitus among Pulmonary TB Patients in a Tertiary Care Hospital of Ahmedabad City, Gujarat

Healthline ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 49-53
Author(s):  
Nirali Patel ◽  
Shikha Jain ◽  
Shraddha Khirid ◽  
Radhika Sharma

Introduction: Diabetes Mellitus and Tuberculosis are two major diseases that often present together and complicate each other at many levels. The epidemic growth of Diabetes Mellitus has occurred in developing countries where Tuberculosis (TB) is highly endemic. As a result, Diabetes Mellitus and TB are increasingly present together. Objectives: To estimate the prevalence of diabetes in tuberculosis patients currently on DOTS treatment and to determine the socio-demographic factors associated with it. Method: A cross sectional study was carried out among pulmonary TB patients receiving DOTS treatment. Total 340 patients were included using convenient sampling who received treatment between August and October 2018. Results: Out of 340 patients, 208 (61%) were males and 132 (39%) were females. The prevalence of diabetes in patients of tuberculosis was found to be 11.5%. Among diabetics, 59% had only diabetes and 41% had other co-morbid disease apart from it. About 56.4% of diabetic TB patients were consuming tobacco. Age, Illiteracy, re-treatment regime were significantly associated with presence of diabetes among TB patients.Conclusion: Diabetes was found to be prevalent in 11.5% of the patients of tuberculosis. Diabetes is significantly associated with the severity of TB, old age and literacy of the TB patients in this study.

Author(s):  
Sujeet A. Divhare ◽  
Satyashil Ingale

Background: Potential importance of drug –drug interactions (DDIs) is increasing as polypharmacy becomes more prevalent. Because additional data on the incidence and pattern of potential DDIs among diabetic patients are lacking in India, and supplemental pharmacodynamic or clinical outcome information is needed to address importance of a drug- drug interaction. Aim and objectives: To identify and analyze the pattern of DDIs in patients being prescribed anti-diabetic drugs in a tertiary care hospital. Material and Methods: This prospective cross-sectional study was carried out for a period of three months in 200 Type 2 diabetes mellitus (Type 2 DM) patients who were taking at least one antidiabetic agent during the period of past six months, of any age and either sex admitted in medicine ward of a tertiary care teaching hospital. Only one prescription was included for each patient on his/her 3rd day of hospitalization in the ward. Results: A total of 1217 drugs were prescribed in 200 prescriptions, resulting in an average of 6.1 drugs per prescription. A total of 637 potential DDIs were noted. The majority were seen in middle aged and elderly people. No overall difference was detected in the patients on insulin or metformin therapy taking or not taking additional drugs with the potential to interact. Worse control was found in the group of patients on sulphonylurea therapy taking interacting drugs (P <0.05). This difference was most marked in the group of patients over 60 years of age, who also had the highest intake of potentially interacting drugs (57%; <35 years-37%). Conclusion: Antidiabetic drugs have numerous interactions. A good practice is to use a drug­–drug interaction checker if any questions arise, several are available online. Quality care starts with the clinician obtaining a complete medication list for each patient at the start of each visit. Keywords: diabetes mellitus, drug interactions, hypoglycemic agents, drug therapy, co-morbidity, polypharmacy


2021 ◽  
Vol 17 (2) ◽  
pp. 125-128
Author(s):  
Hamna Javed ◽  
Haider Zaigham Baqai ◽  
Saadia Khan Baloch

ABSTRACT: Objective:           To determine the prevalence of the recurrence rate of Pulmonary tuberculosis (TB) in successfully treated patients in a tertiary care hospital in Pakistan. Methodology:           This cross-sectional study was conducted at Benazir Bhutto Hospital Rawalpindi. The study duration was from 01-January-2019 to 01-August-2020. During the study period, a total number of ten thousand nine hundred ninety-seven (10997) patients presented in the chest clinic of the hospital and were included in this study, these patients were re-treatment TB patients and presented with the first-time diagnosis of TB. The recurrence rate was the primary end-point of this study. Results: There were 10997 patients included in this study, out of these 642 (5.83%) patients presented with recurrence. Out of a total of 642 recurrence cases, 533 (83%) patients were SS positive, and the remaining 109 (17%) were SS negative. Out of 642, 341 (53.1%) patients were male and 301 (46.9%) patients were female. Regarding age, most of the patients were in the age group 16-30 (49%), 93 (23%) were in the age group 31-45 years. Regarding the timing of recurrence, 372 (58%) patients presented with in one year, 109 (17%) presented in 12-24 months, 52 (8%) presented in 24-36 months. Conclusion:           Based on our study, the recurrence rate of pulmonary TB was 5.83% in the Pakistani population. The recurrence rate is high in patients having age 15-45 years and recurrence occurs in 58% of patients within first year after successful treatment of Pulmonary TB.


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