scholarly journals Interleukin-4 Gene Polymorphisms in Type 2 Diabetes Mellitus in Medan, Indonesia

Author(s):  
Milahayati Daulay ◽  
Mutiara Indah Sari
2020 ◽  
Vol 8 (A) ◽  
pp. 833-836
Author(s):  
Milahayati Daulay ◽  
Mutiara Indah Sari

   BACKGROUND: Various studies have shown variations in the interleukin-4 (IL) gene associated with type 2 diabetes mellitus (T2DM) in different populations and ethnicities. AIM: The objective of this study was to determine the genetic variation of the IL-4 −33 C/T gene in some T2DM patients compared with healthy control in Medan, Sumatera Utara province, Indonesia. METHODS: DNA from T2DM patients and healthy control was isolated, then the determination of the IL-4 −33 C/T gene polymorphism was carried out using the polymerase chain reaction-restriction fragment length polymorphism technique. RESULTS: In all samples of this study, IL-4 −33 C/T gene polymorphisms were found in patients with T2DM and healthy control but were not statistically significant. CONCLUSION: The IL-4 −33 C/T gene polymorphism has no relationship with the incidence of T2DM in a portion of our population in Medan, Sumatera Utara province, Indonesia.


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pp. 265-272 ◽  
Author(s):  
Fang-Jian CHEN ◽  
Hong YU ◽  
Fan FAN ◽  
Jian-Xin LU

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2010 ◽  
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Fatma Yesim Demirci ◽  
Latonya Been ◽  
Lyda Ortega ◽  
Sarju Ralhan ◽  
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PLoS ONE ◽  
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pp. e108587 ◽  
Author(s):  
Pawel P. Wolkow ◽  
Wladyslaw Kosiniak-Kamysz ◽  
Grzegorz Osmenda ◽  
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Beata Bujak-Gizycka ◽  
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pp. 2205-2215 ◽  
Author(s):  
V.J. Picos-Cárdenas ◽  
E. Sáinz-González ◽  
A. Miliar-García ◽  
A. Romero-Zazueta ◽  
R. Quintero-Osuna ◽  
...  

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