scholarly journals TREATMENT AND PREVENTION OF POST-CHEMOTHERAPY THROAT DRYING IN ONCOLOGY PATIENTS WITH NATURAL DRUG – ISLA MINT

Author(s):  
TINATIN GOGNADZE ◽  
SHORENA TSIKLAURI ◽  
GHANATE RAHUL KUMAR ◽  
RAGINI RAGINI ◽  
NIKHI L KUMAR

Isla Mint is a natural drug, which has been used to treat the inflammation and dryness of oral mucosa, is extracted from the plant Iceland moss (Scientific name: Cetraria islandica). It contains substances that are characterized by its protective mucous membrane effects and its anti-irritant effect. The dose and therapeutic effectiveness have been analyzed in this clinical study.

2020 ◽  
Vol 16 (2) ◽  
pp. 5-10
Author(s):  
Irina Galimova ◽  
Irina Usmanova ◽  
Zarema Hismatullina ◽  
Yigal Granot ◽  
Olga Guryevskaya ◽  
...  

Subject. Despite the many pathogenetic links in the lesions of the gastrointestinal tract and oral mucosa, unresolved issues related to their etiopathogenesis, diagnosis and high-quality therapeutic and preventive measures. Among the various pathological processes manifesting on the oral mucosa, recurrent aphthous stomatitis is a chronic disease characterized by the appearance of secondary pathomorphological elements (aphthae) in response to the development of acute proliferative inflammation. The goal is the analysis and systematization of literature data on the problem of damage to the oral mucosa in acid-dependent diseases of the gastrointestinal tract. Methodology. Recurrent aphthae of the oral cavity belong to the chronic pathology of the oral mucosa, are characterized by a prolonged course and periodic relapses, which are most often associated with the state of somatic status, including the presence of acid-dependent diseases of the gastrointestinal tract. Results. The main pathomorphological element inherent in this pathology is aphtha. Its localization is the mucous membrane of the vestibule of the oral cavity, cheeks, and lateral surface of the tongue, visually oval or round, covered with a dirty white fibrinous coating. Treatment of recurrent aphthae of the oral cavity includes a complex consisting of general systemic therapy of the underlying disease. Local treatment includes the use of antihistamines, immunocorrection, drugs that increase nonspecific hypersensitivity, normalization of cellular metabolism and stimulate nonspecific defense mechanisms, vitamin therapy and physiotherapy methods. Conclusions. This treatment should ultimately be aimed at eliminating not only pain, but also at increasing local immunity factors, combating pathogenic microflora and promoting the epithelization of pathological processes on the oral mucosa. Of great importance in the treatment and prevention of recurrent aphthae is a comprehensive examination of the patient in order to identify risk factors.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroki Hihara ◽  
Ryo Tagaino ◽  
Jumpei Washio ◽  
Kittipong Laosuwan ◽  
Dimas Prasetianto Wicaksono ◽  
...  

Abstract Background Removal of oral biofilm from the oral mucosa is essential for preventing risk of respiratory and gastrointestinal infection in elderly people. Currently, no device is available which can remove oral biofilm from oral mucosa effectively and safely. Therefore, the effectiveness and safety of the Micro Scale Mist UNIT (MSM-UNIT), a newly developed dental plaque removal device utilizing high speed sprays of fine water droplets, were evaluated for biofilm removal, including the rate and surface roughness for simulated tooth surface and mucous membrane. Methods Simulated tooth and oral mucosa coated with an artificial biofilm of Streptococcus mutans were used for evaluation of effectiveness, with uncoated substrates as the controls. The MSM-UNIT and a conventional air ablation device were operated under recommended instructions. The effectiveness was evaluated from the rate of removal of the biofilm, and the safety was evaluated from the damage observed by scanning electron microscope and surface roughness. Results The biofilm removal rate of the MSM-UNIT was significantly higher than that of AIRFLOW. Little damage was observed in the area treated by the MSM-UNIT. The surface roughness of the MSM-UNIT treated area on simulated tooth surface and oral mucosa showed no significant difference to the control area. In contrast, cracks and powder were observed in the area treated by AIRFLOW. In particular, the surface roughness of the AIRFLOW treated area for Toughsilon was significantly larger than that of the control. Conclusions The MSM-UNIT could be used safely and effectively for removing biofilm not only on simulated tooth surfaces but also simulated mucous membrane. The MSM-UNIT has no harmful effect on teeth or oral mucosa, and may be used for comprehensive oral care for patients during nursing care and the perioperative period.


2021 ◽  
Vol 0 (14) ◽  
pp. 91-100
Author(s):  
Vera Usevich ◽  
N. Kurochkina ◽  
M. Drozd ◽  
Ol'ga Petrova

Abstract. The prevalence of coccidiosis diseases of various animal species has a global scale, so this problem has attracted the attention of veterinary specialists around the world. The purpose of this study was to study the specific features of the species composition and laboratory diagnostics of eimeriosis in young ruminants and to evaluate the effectiveness of treatment and prevention when using drugs from different groups. The material for the study was goats and calves. The research was carried out on the basis of two farms of the same agricultural holding in the Sverdlovsk region. Diagnostics was performed based on clinical and laboratory studies. Results of the study. The main pathogens in the goat breeding complex in goats of different ages were identified: the main causative agent of coccidiosis in 120-day-old goats was Eimeria arloingi, which accounted for 54 % of all detected oocysts in the samples. Eimeriosis occurred as a mixed invasion of Eimeria arloingi with Eimeria ninaekohlyakimovae (33 %) and Eimeria intracata (13 %). Eimeria arloingi (68 %), in 21-days-old goats – Eimeria ninaekohlyakimovae (32 %). Eimeriosis caused by Eimeria bovis was detected in 30-days-old calves (100 %). The article describes the results of using various anticoccidial drugs in the treatment and prevention of eimeriosis. A comparative evaluation of the therapeutic effectiveness of known coccidiostatics is given. The economic efficiency of different groups of drugs was evaluated. The scientific novelty lies in the fact that the morphological and quantitative assessment of parasitocenoses in eimeriosis in young ruminants was carried out. A comparative evaluation of the effectiveness of various traditional remedies and a new drug for the treatment of eimeriosis in calves and goats was carried out. Conclusion. Not all of the drugs used have the same therapeutic effectiveness both in terms of treatment time and the quality of elimination of the etiological factor.


2021 ◽  
pp. 20-25
Author(s):  
B.Y. Silenko ◽  
V.M. Dvornik ◽  
Y.I. Silenko

The main cause of prosthetic stomatitis belongs to the chemical and toxic action of the residual monomer of the prosthesis base, which is a protoplasmic poison. Occurrence of prosthetic stomatitis depends not only on quality of production of prosthesis in laboratory though at non-observance of technology indicators of residual monomer can reach 2-5%, but also at individual intolerance at its minimum concentration in a prosthesis after polymerization - 0,2-0 .5%. The aim of our study was to increase the effectiveness of orthopedic treatment of patients with prosthetic stomatitis by coating the plastic of removable prostheses with nanoscale materials. Materials and methods. To solve this goal, we studied the condition of the tissues of the prosthetic place of patients with prosthetic stomatitis with prosthetic removable prostheses with modified plastic. Orthopedic dental treatment of 50 people was examined and performed, including 25 people (the second group, prostheses were not covered with nanoparticles) and 25 people (the third group, prostheses were covered with nanoparticles). The first control group consisted of 10 people without signs of pathology. Prior to treatment, all patients had removable acrylic plastic dentures. The reason for seeking orthopedic care was a violation of masticatory function and the inability to use previously made prostheses due to the development of pain in the soft tissues of the prosthetic place. Complaints of pain were observed in all patients of varying intensity, impaired fixation and stabilization of the prosthesis due to swelling of the mucous membrane of the soft tissues of the prosthetic place, heartburn and dryness were observed in 90% of patients. Complaints were also about speech and aesthetic defects. Patients of III group after two weeks of using prostheses were coated with the inner surface of the prosthesis, which is in direct contact with the mucous membrane of the prosthetic place with molecules of fullerene C60, by magnetron sputtering. For this purpose, the prostheses were removed from the patients for several days and returned after the coating with the nanomaterial, after which the observation was continued. The results. After coating the prostheses in patients of group III with Fullerene C60, we observed the disappearance of inflammation of the mucous membrane under the prosthesis and patients noted the absence of discomfort. Рatients in II group had a negative dynamics in 80% and had diffuse inflammation of the mucous membrane under the prosthesis. Within 3 months of use, 18 patients (72%) in II group reported that they stopped using removable dentures during the day, due to unpleasant pain under the prosthesis, and used only during meals and during conversations. In contrast to II group, patients in III group did not notice discomfort when using plate prostheses. Conclusions. Obtained in the course of the work convincingly prove the effectiveness of the use of removable plate prostheses with nanocoating for the treatment and prevention of prosthetic stomatitis in patients. This is evidenced by the data of objective examination and the disappearance of complaints from patients.


2020 ◽  
Vol 22 (100) ◽  
pp. 71-77
Author(s):  
N. M. Khomyn ◽  
A. R. Mysak ◽  
S. V. Tsisinska ◽  
V. V. Pritsak ◽  
N. V. Nazaruk ◽  
...  

Periodontal disease is known to be the most common and serious health problem in dogs today. Despite the rather large arsenal of medicinal substances, the problem of treatment and prevention of periodontal disease remains relevant. Based on this, the purpose of the work was to study the features of chronic catarrhal gingivitis and to develop an effective treatment regimen for dentistically ill dogs. For research, two groups of animals with chronic catarrhal gingivitis were formed in 5 dogs in each (control and experimental), selected on the principle of analogues in terms of age, character and localization of the inflammatory process. Animals of the control and experimental groups were performed tartar removal, irrigation of the oral cavity with water and drying of the mucosa with a sterile gauze swab. Dogs of the control group on the mucous membrane was applied 1 ml of septogel 2 times a day, and the experimental – argumentistin 2 times a day. Before and after the procedures on the mucous membrane was applied a 3 % solution of hydrogen peroxide. It was determined the prevalence of dental disease in dogs, the influence of microflora on the condition of the oral cavity of dogs with chronic catarrhal gingivitis, the clinical condition and the main indices and samples were studied, reflecting the intensity of the inflammatory process in the gums of sick dogs and was developed a method of treatment. The results of researches have shown that the use of argumentistin in the complex treatment of dogs with chronic catarrhal gingivitis helps to reduce the recovery period by 5 days.


1980 ◽  
Vol 26 (6) ◽  
pp. 1497-1507
Author(s):  
Teruo AMAGASA ◽  
Emiko YOKOO ◽  
Katsuhiko YUKI ◽  
Hiroshi IWAKI ◽  
Tadao TACHIBANA ◽  
...  

2021 ◽  
Vol 31 (1) ◽  
pp. 111-112
Author(s):  
Roberto Maglie ◽  
Corinne Orsini ◽  
Beatrice Bianchi ◽  
Emiliano Antiga ◽  
Elisa Cinotti

Oncology ◽  
2017 ◽  
Vol 93 (3) ◽  
pp. 157-163 ◽  
Author(s):  
Marina Hierl ◽  
Jochen Pfirstinger ◽  
Reinhard Andreesen ◽  
Ernst Holler ◽  
Stephanie Mayer ◽  
...  

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