Determination of Particle Size in Latex

1953 ◽  
Vol 26 (2) ◽  
pp. 481-486 ◽  
Author(s):  
E. G. Cockbain
Keyword(s):  
Particle Size ◽  
Sodium Dodecyl Sulfate ◽  
Natural Rubber ◽  
Sodium Dodecyl ◽  
Average Particle ◽  
Particle Sizes ◽  
Sulfate Concentration ◽  
Titration Method ◽  
Dodecyl Sulfate

Abstract The soap titration method of determining average particle sizes in synthetic latexes has been modified so as to make it applicable to natural rubber latexes. The method consists essentially in determining the distribution of an added detergent (sodium dodecyl sulfate) between the rubber and aqueous phases at a pH of approximately 6.0, the total dodecyl sulfate concentration being just sufficient for the formation of micelles in the aqueous phase. The average particle sizes of nine ammoniated latexes have been measured, including centrifuged and electrodecanted concentrates, two clonal field latexes and a sample of latex skim.

scholarly journals Development of Polymer and Surfactant Based Naringenin Nanosuspension for Improvement of Stability, Antioxidant, and Antitumour Activity

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Shadab Md ◽  
Nabil A. Alhakamy ◽  
Sohail Akhter ◽  
Zuhier A. Y. Awan ◽  
Hibah M. Aldawsari ◽  
...  
Keyword(s):  
Particle Size ◽  
Antitumor Activity ◽  
Sodium Dodecyl Sulfate ◽  
Drug Release ◽  
Size Distribution ◽  
Hydroxypropyl Methylcellulose ◽  
Sodium Dodecyl ◽  
Average Particle ◽  
Dodecyl Sulfate

Nanosuspensions are widely reported to enhance the solubility of poorly soluble drugs. In addition to enhancement in solubility, improvement of stability and therapeutic efficacy would be an added advantage. In the present study, premilling and subsequent high-pressure homogenization were carried out to produce naringenin nanosuspension. Hydroxypropyl methylcellulose and sodium dodecyl sulfate were evaluated for their performance as stabilizers under various homogenization cycles. The prepared nanosuspensions were studied for average particle size and size distribution, zeta potential, solubility, drug release, antioxidant activity, and in vitro antitumor activity. It was observed that both hydroxypropyl methylcellulose-stabilized nanosuspension and sodium dodecyl sulfate-stabilized nanosuspension produced an enhancement in physical stability, antioxidant potential, and in vitro cytotoxicity compared with naringenin. Furthermore, hydroxypropyl methylcellulose-stabilized nanosuspension was found to be better than sodium dodecyl sulfate-stabilized nanosuspension in terms of particle size and size distribution, storage stability, and drug release. This study showed that nanosuspension formulations could be a potential strategy for improving dissolution and antitumor activity of naringenin.

scholarly journals Determination of Simvastatin by Voltammetry Method at Screen-Printed Electrode Modified by Graphene Oxide Nanosheets and Sodium Dodecyl Sulfate

2022 ◽  
Author(s):  
Abolfazl Darroudi ◽  
Saeid Nazari ◽  
Seyed Ali Marashi ◽  
Mahdi Karimi-Nazarabad
Keyword(s):  
Graphene Oxide ◽  
Sodium Dodecyl Sulfate ◽  
Limit Of Detection ◽  
Sodium Dodecyl ◽  
Screen Printed Electrode ◽  
Support Electrolyte ◽  
Limit Of Quantitation ◽  
Dodecyl Sulfate ◽  
Screen Printed

Abstract An accurate, rapid, simple, and novel technique was developed to determine simvastatin (SMV). In this research, a screen-printed electrode (SPE) was deposited with graphene oxide (GO) and sodium dodecyl sulfate (SDS), respectively. For the first time, the handmade modified SPE measured the SMV by differential pulse voltammetry (DPV) with high sensitivity and selectivity. The results of cyclic voltammetry indicated the oxidation irreversible process of SMV. Various parameters (pH, concentration, scan rate, support electrolyte) were performed to optimize the conditions for the determination of SMV. Under the optimum experiment condition of 0.1 M KNO3 as support electrolyte and pH 7.0, the linear range was achieved for SMV concentration from 1.8 to 36.6 µM with a limit of detection (LOD), and a limit of quantitation (LOQ) of 0.06 and 1.8 µM, respectively. The proposed method was successfully utilized to determine SMV in tablets and urine samples with a satisfactory recovery in the range of 96.2 to 103.3%.

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