scholarly journals Comparison and evaluation of acid reflux esophagitis animal models

10.52586/5052 ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 1599-1606
Author(s):  
Yanping Tang ◽  
Lei Liu ◽  
Xi Liu ◽  
Shuhong Li ◽  
Simiao Liu ◽  
...  
Keyword(s):  
Animal Models ◽  
Reflux Esophagitis ◽  
Acid Reflux

GERD an ayurvedic management : A review article

2019 ◽  
Vol 7 (05) ◽  
Author(s):  
Ramesh Pawar ◽  
Gadve N. B.
Keyword(s):  
Present Article ◽  
Reflux Esophagitis ◽  
Acid Reflux ◽  
Review Article ◽  
Satisfactory Treatment ◽  
Spicy Food

GERD correlated with the disease Amlapitta, described in ayurveda. GERD occurs when digestive juices moves upward from the stomach in to the esophagus  causing Acid reflux. Lifestyle eating too late at night , spicy food , alcohol , smoking tobacco,  coffee , tea ,causes GERD. heartburn , regurgitation and difficulty swallowing are common symptoms seen in GERD. till date no satisfactory treatment is available for GERD with reflux esophagitis. In the present article an attempt has been made to emphasis on herbal option for GERD.

scholarly journals Increased Immunoreactivity of Cathepsins in the Rat Esophagus under Chronic Acid Reflux Esophagitis

2014 ◽  
Vol 62 (9) ◽  
pp. 645-660 ◽  
Author(s):  
Masayuki Suyama ◽  
Masato Koike ◽  
Daisuke Asaoka ◽  
Hiroki Mori ◽  
Masako Oguro ◽  
...  
Keyword(s):  
Reflux Esophagitis ◽  
Acid Reflux

PS01.142: THE IMPACT OF CERVICAL LYMPH NODE DISSECTION ON ACID AND DUODENOGASTROESOPHAGEAL REFLUX AFTER INTRATHORACIC ESOPHAGOGASTROSTOMY FOLLOWING TRANSTHORACIC ESOPHAGECTOMY

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 90-90
Author(s):  
Masahide Fukaya ◽  
Kazushi Miyata ◽  
Keita Itatsu ◽  
Soichiro Asai ◽  
Kimitoshi Yamazaki ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Dissection ◽  
Reflux Esophagitis ◽  
Cervical Lymph Node ◽  
Acid Reflux ◽  
Transthoracic Esophagectomy ◽  
Node Dissection ◽  
Cervical Lymph Node Dissection ◽  
Duodenogastroesophageal Reflux ◽  
The Impact

Abstract Background The aim of this study was to evaluate the impact of cervical lymph node dissection on acid and duodenogastroesophageal reflux (DGER) in patients undergoing transthoracic esophagectomy with gastric tube reconstruction and intrathoracic esophagogastrostomy. Methods Thirty one patients receiving transthoracic esophagectomy gastric tube reconstruction by intrathoracic esophagogastrostomy were subjected and divided into two groups: two field lymph node dissection group (the 2F group) and three field lymph node dissection group (the 3F group). All patients underwent 24h pH and bilirubin monitoring and gastrointestinal endoscopy one year after surgery. The results of 24h pH and bilirubin monitoring, endoscopic findings, and reflux symptoms, were compared between two groups. Results No acid reflux was observed in the 2F group, whereas it was observed in 6 (40%) of the 3F group (P = 0.023). DGER was observed in 2 patients (13%) of the 2F groups, whereas it was observed in 8 (53%) of the 3F group (P = 0.007). The percentage time of acid reflux in the 3F group was significant higher than that in the 2F group (median 0.8 vs 0%, P = 0.008). The percentage time of bile reflux in the 3F group was also significantly higher than that in the 2F group (median 2.600 vs 0%, P = 0.027). Four patients (25%) had reflux esophagitis in the 2F group, and nine patients (60%) had reflux esophagitis in the 3F group (P = 0.048). Conclusion Cervical lymph node dissection increases acid reflux and duodenogastroesophageal reflux, and can lead to the increase of the incidence of reflux esophagitis in patient with intrathoracic esophagogastrostomy. Disclosure All authors have declared no conflicts of interest.

Altered localization and expression of tight-junction proteins in a rat model with chronic acid reflux esophagitis

2005 ◽  
Vol 40 (8) ◽  
pp. 781-790 ◽  
Author(s):  
Daisuke Asaoka ◽  
Hiroto Miwa ◽  
Shu Hirai ◽  
Akimitsu Ohkawa ◽  
Akihiko Kurosawa ◽  
...  
Keyword(s):  
Tight Junction ◽  
Reflux Esophagitis ◽  
Rat Model ◽  
Acid Reflux ◽  
Tight Junction Proteins ◽  
Junction Proteins

Comparative efficacy of acid reflux inhibition by drug therapy in reflux esophagitis

1991 ◽  
Vol 26 (2) ◽  
pp. 137-144 ◽  
Author(s):  
Toshikazu Sekiguchi ◽  
Toshio Nishioka ◽  
Tsutomu Matsuzaki ◽  
Masashi Sugiyama ◽  
Motoyasu Kusano ◽  
...  
Keyword(s):  
Drug Therapy ◽  
Reflux Esophagitis ◽  
Acid Reflux ◽  
Comparative Efficacy

scholarly journals Increase in Thermo-sensitive TRP Channel-Expressing Neurons in Acid Reflux Esophagitis Model Rats

2019 ◽  
Vol 92 (0) ◽  
pp. 1-P-078
Author(s):  
Megumi Koide ◽  
Tomoharu Shinoki ◽  
Kenjiro Matsumoto ◽  
Kimihito Tashima ◽  
Syunji Horie
Keyword(s):  
Reflux Esophagitis ◽  
Acid Reflux ◽  
Trp Channel

scholarly journals Effect of Evodiae Fructus and Arecae Semen Mixture on Esophageal Mucosa in Chronic Acid Reflux Esophagitis

2021 ◽  
Vol 27 (2) ◽  
pp. 77-87
Author(s):  
Jin A Lee ◽  
Mi-Rae Shin ◽  
Hae-Jin Park ◽  
Seong-Soo Roh
Keyword(s):  
Reflux Esophagitis ◽  
Acid Reflux ◽  
Esophageal Mucosa

scholarly journals Reflux Esophagitis and Fatigue: Are They Related?

2020 ◽  
Author(s):  
Sung-Goo Kang ◽  
Hyun jee Hwang ◽  
Youngwoo Kim ◽  
Junseak Lee ◽  
Jung Hwan Oh ◽  
...  
Keyword(s):  
Reflux Esophagitis ◽  
Daytime Sleepiness ◽  
Depression Scale ◽  
Acid Reflux ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Symptomatic Group ◽  
Screening Endoscopy ◽  
Symptomatic Gerd ◽  
Gerd Symptoms

Abstract Background: Gastroesophageal reflux disease (GERD) is a chronic, recurrent disease. Reflux esophagitis can interfere with sleep via acid reflux, which could cause daytime sleepiness or fatigue. However, little is known about the association between reflux esophagitis and fatigueObjectives: We evaluated the association between fatigue and reflux esophagitis in subjects seen at health check-ups.Methods: Consecutive patients who were scheduled for screening endoscopy were enrolled prospectively at the Comprehensive Medical Examination Center of St. Vincent Hospital and Eunpyeong St. Mary's Hospital, Korea. Three validated questionnaires were used to assess fatigue, daytime hypersomnolence, anxiety, and depression: the Multidimensional Fatigue Inventory-Korean version (MFI-K), Epworth Sleepiness Scale (ESS), and Hospital Anxiety and Depression Scale (HADS).Results: We investigated 497 consecutive eligible subjects. The reflux esophagitis and symptomatic GERD groups comprised 103 (20.7%) and 92 (18.5%) subjects, respectively. The MFI-K total, ESS, HADS-anxiety, and HADS-depression scores did not differ between the esophagitis and non-esophagitis groups (50.0±11.5 vs. 49.7±10.9, P=0.769; 6.2±2.8 vs. 6.1±3.1, P=0.819; 5.8±3.1 vs. 5.2±3.2, P=0.069; 6.2±3.6 vs. 6.0±3.3, P=0.527). However, the MFI-K total, ESS, HADS-anxiety, and HADS-depression scores were higher in the symptomatic group than in the non-symptomatic group (54.7±12.7 vs. 48.6±10.3, P<0.001; 7.1±3.5 vs. 5.9±2.9, P=0.002; 6.4±3.3 vs. 5.1±3.1, P<0.001; 7.5±4.0 vs. 5.7±3.1, P<0.001). In addition, HADS-depression was correlated with the MFI-K score (P<0.001).Conclusion: There was no statistically significant association in which reflux esophagitis could cause daytime sleepiness, fatigue, anxiety, or depression, but GERD symptoms were associated with all of these. Depression was also associated with fatigue. Further studies should clarify the association between fatigue and reflux esophagitis.

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