Effect of Peritoneal Dialysis Treatment on Left Ventricular Systolic and Diastolic Functions in Patients with End-Stage Renal Disease

2014 ◽  
Vol 23 (3) ◽  
pp. 202-209
Author(s):  
Feridun Kavuncuoglu ◽  
Aydin Unal ◽  
Mikail Yarlıoglues ◽  
Mustafa Duran ◽  
Ismail Kocyigit ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Left Ventricular ◽  
Dialysis Treatment ◽  
Stage Renal Disease ◽  
End Stage ◽  
Diastolic Functions

scholarly journals Discover, analysis, and interpretation of problems and comparing satisfaction of hemodialysis and peritoneal dialysis patients: patients' perspective

2020 ◽  
Author(s):  
Ghazanfar Rafiee ◽  
Jamshid Roozbeh
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Dialysis Patients ◽  
Dialysis Treatment ◽  
Patient’S Satisfaction ◽  
Exploratory Approach ◽  
Dialysis Method ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background: End-stage renal disease is an irreversible and progressive loss of kidney function and it can be fatal without hemodialysis, peritoneal dialysis or kidney transplantation. Hemodialysis is a type of treatment where the patient is connected to a machine through a catheter via veins for twice or three times a week for approximately four hours. Alternatively, peritoneal dialysis is carried out with a plastic catheter insertion into the abdomen through which dialysis fluid (glucose) enters and is taken out. This study aimed to discover, analyze, interpret and compare end-stage renal disease patient's satisfaction with hemodialysis and peritoneal dialysis with an emphasis on complications and problems that was created during dialysis treatment.Methods: this study a qualitative exploratory approach was used at Shiraz hemodialysis and peritoneal dialysis centers 2017-2018. In these centers there were 345 ESRD patients who were receiving dialysis. A purposeful sample of 35 hemodialysis and 30 peritoneal dialysis patients were interviewed. The data were collected through interview. Each session lasted for 50 minutes. Initially 12 open-ended questions were developed and used to stimulate discussions in sessions. Directed content analysis was used for analyzing the transcribed data. After giving a code to each line or incidence, codes were then compared for similarity and differences, merged together, and categorized. Results: Themes of Fatigue experience, Insomnia, Wasting time, Travel and leisure time activities limitations, Hypotension, Dissatisfaction and satisfaction with hemodialysis, Peritoneal catheter problems, peritoneal dialysis difficulties and limitations, satisfaction from peritoneal dialysis emerged. Each dialysis method has its own problems. Some problems and limitations were more emphasized on by patients. Conclusion: Each dialysis method has its own problems. Some problems and limitations were more emphasized on by patients.

Abstract 145: Endothelial Dysfunction: A Key Determinant of Ventricular Dysfunction in End-Stage Renal Disease

2015 ◽  
Vol 35 (suppl_1) ◽  
Author(s):  
Ruth Dubin ◽  
Isabella Guajardo ◽  
Claire Mills ◽  
Catherine Donovan ◽  
Lauren Beussink-Nelson ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Endothelial Dysfunction ◽  
Renal Disease ◽  
Endothelial Function ◽  
End Stage Renal Disease ◽  
Global Longitudinal Strain ◽  
Left Ventricular ◽  
High Rate ◽  
Stage Renal Disease ◽  
End Stage

Objectives: Mechanisms underlying the high rate of cardiovascular mortality in patients with end-stage renal disease (ESRD) are poorly understood. We sought to determine whether endothelial dysfunction is associated with left ventricular (LV) and right ventricular (RV) dysfunction in ESRD. Methods: Stable patients with ESRD (n=75) underwent measurement of: (1) flow-mediated dilation (FMD), using upper arm brachial occlusion, and (2) cardiac mechanics, using speckle-tracking echocardiography (STE). Microvascular function was measured as the velocity time integral (VTI) of hyperemic blood flow following cuff deflation. Eight participants returned for repeat endothelial testing at 1-week intervals. Results: The mean±SD age was 54±11 years, 38% were diabetic, and 17% were on peritoneal dialysis. FMD median (IQR) was 4.7% (2.7-6.9%) and VTI was 0.62m (0.45-0.72m). After adjustment for age, gender, diabetes and systolic blood pressure, lower VTI was associated with worse RV longitudinal free wall strain (β=6.3% per 1m VTI; 95% CI [1.8, 11]; p=0.007). In patients with ejection fraction ≥50%, lower FMD was associated with worse LV global longitudinal strain (β=0.36% per 1% FMD; 95% CI [0.11,0.61]; p=0.005). Mean absolute differences at one week for FMD and VTI were 1.8% and 0.19m. Conclusions: In a diverse cohort of patients on hemo- or peritoneal dialysis, worse endothelial function was associated with LV and RV mechanics after adjustment for clinical factors. Repeatability of FMD and VTI were in accordance with current guidelines. Future studies are needed to investigate whether therapies that improve endothelial function could improve cardiac function in ESRD.

Left ventricular hypertrophy in end-stage renal disease on peritoneal dialysis

1987 ◽  
Vol 60 (4) ◽  
pp. 418-419 ◽  
Author(s):  
Mark Eisenberg ◽  
Sarah Prichard ◽  
Paul Barre ◽  
Robert Patton ◽  
Tom Hutchinson ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Left Ventricular Hypertrophy ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Stage Renal Disease ◽  
End Stage

Outcomes of infants <28 days old treated with peritoneal dialysis for end-stage renal disease

2009 ◽  
Vol 24 (10) ◽  
pp. 2035-2039 ◽  
Author(s):  
Michelle N. Rheault ◽  
Jurat Rajpal ◽  
Blanche Chavers ◽  
Thomas E. Nevins
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Coronary microvascular dysfunction is associated with degree of anaemia in end‐stage renal disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ashwin Radhakrishnan ◽  
Luke C. Pickup ◽  
Anna M. Price ◽  
Jonathan P. Law ◽  
Kirsty C. McGee ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Renal Disease ◽  
Kidney Transplant ◽  
End Stage Renal Disease ◽  
Microvascular Dysfunction ◽  
Left Ventricular ◽  
Coronary Microvascular Dysfunction ◽  
Transplant Candidates ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background Coronary microvascular dysfunction (CMD) is common in end-stage renal disease (ESRD) and is an adverse prognostic marker. Coronary flow velocity reserve (CFVR) is a measure of coronary microvascular function and can be assessed using Doppler echocardiography. Reduced CFVR in ESRD has been attributed to factors such as diabetes, hypertension and left ventricular hypertrophy. The contributory role of other mediators important in the development of cardiovascular disease in ESRD has not been studied. The aim of this study was to examine the prevalence of CMD in a cohort of kidney transplant candidates and to look for associations of CMD with markers of anaemia, bone mineral metabolism and chronic inflammation. Methods Twenty-two kidney transplant candidates with ESRD were studied with myocardial contrast echocardiography, Doppler CFVR assessment and serum multiplex immunoassay analysis. Individuals with diabetes, uncontrolled hypertension or ischaemic heart disease were excluded. Results 7/22 subjects had CMD (defined as CFVR < 2). Demographic, laboratory and echocardiographic parameters and serum biomarkers were similar between subjects with and without CMD. Subjects with CMD had significantly lower haemoglobin than subjects without CMD (102 g/L ± 12 vs. 117 g/L ± 11, p = 0.008). There was a positive correlation between haemoglobin and CFVR (r = 0.7, p = 0.001). Similar results were seen for haematocrit. In regression analyses, haemoglobin was an independent predictor of CFVR (β = 0.041 95% confidence interval 0.012–0.071, p = 0.009) and of CFVR < 2 (odds ratio 0.85 95% confidence interval 0.74–0.98, p = 0.022). Conclusions Among kidney transplant candidates with ESRD, there is a high prevalence of CMD, despite the absence of traditional risk factors. Anaemia may be a potential driver of microvascular dysfunction in this population and requires further investigation.

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