scholarly journals Metacarpal chondrosarcoma, from negligence to rareness : a case report and review of the literature

2021 ◽  
Vol 87 (3) ◽  
pp. 541-543
Author(s):  
Pauline Ollero ◽  
Sophie Vanden Dungen ◽  
Katerina Cermak ◽  
Louis Kinnen
Keyword(s):  
Unusual Case ◽  
Blood Analysis ◽  
Subtotal Resection ◽  
Malignant Bone Tumor ◽  
Review Of The Literature ◽  
Primary Malignant Bone Tumor ◽  
Left Hand ◽  
Aggressive Tumor ◽  
Loss Of Motion ◽  
Common Primary Malignant Bone

Chondrosarcoma is rarely found in the extremities but it remains the most common primary malignant bone tumor of the hand. We report an unusual case of a 46-year-old man with a huge chondrosarcoma on his left hand that has been evolving for more than 30 years. The mass has always been painless, the symptoms were only the deformation and a slight loss of motion. We did a subtotal resection since the patient refused the amputation. The investigation, which in- cluded thoracoabdominal tomography, scintigraphy and blood analysis, turned out to be negative. In the literature, CS are usually associated with a locally destructive growth but metastasis hasn’t been often described. CS seems to be an aggressive tumor locally but, unlike in other sites, it seems to rarely metastasize when in the hands.

Malignant Chondroid Matrix Bone Tumors

2019 ◽  
pp. 268-274
Author(s):  
Benjamin D. Levine ◽  
Leanne L. Seeger
Keyword(s):  
Multiple Myeloma ◽  
Bone Tumor ◽  
Bone Tumors ◽  
Histological Grade ◽  
Imaging Features ◽  
Malignant Bone Tumor ◽  
Primary Malignant Bone Tumor ◽  
The Third ◽  
Chondroid Matrix ◽  
Common Primary Malignant Bone

Chapter 55 discusses malignant chondroid matrix bone tumors. Chondrosarcoma is a malignant bone tumor of cartilage origin. It represents the third most common primary malignant bone tumor, after multiple myeloma and osteosarcoma. Conventional intramedullary chondrosarcoma is its most common subtype, with rarer subtypes that include clear cell, mesenchymal, dedifferentiated, and periosteal chondrosarcoma. Secondary chondrosarcoma represents a lesion that arises in a preexisting benign chondroid lesion (enchondroma or osteochondroma). Chondrosarcomas demonstrate some specific imaging features that can improve diagnostic accuracy and help guide clinical management. Histological grade of central chondrosarcoma usually dictates surgical management. As with other sarcomas, outcome of chondrosarcoma depends on histological grade, surgical margins, and staging.

Premalignant and Malignant Lesions of the Heterotopic Pancreas in the Esophagus: a Case Report and Review of the Literature

2015 ◽  
Vol 24 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Jan Ulrych ◽  
Vladimir Fryba ◽  
Helena Skalova ◽  
Zdenek Krska ◽  
Tomas Krechler ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Unusual Case ◽  
Accurate Diagnosis ◽  
Heterotopic Pancreas ◽  
Premalignant Lesions ◽  
Resected Specimen ◽  
Review Of The Literature ◽  
Severe Dysphagia ◽  
Malignant Lesions

Heterotopic pancreas is a congenital pathology of the gastrointestinal tract, particularly rare in the esophagus. Both symptomatology and findings during preoperative examinations are non-specific and therefore do not often lead to an accurate diagnosis, which is usually revealed only by histopathological assessment of a resected specimen. We report an unusual case of a patient suffering from severe dysphagia caused by heterotopic pancreas in the distal esophagus with chronic inflammation and foci of premalignant changes. This article also reviews 14 adult cases of heterotopic pancreas in the esophagus previously reported in the literature, with the aim of determining the clinical features of this disease and possible complications including rare premalignant lesions and malignant transformation. Especially with regard to those complications, we suggest that both symptomatic and incidentally found asymptomatic lesions should be resected.

Capillary haemangioma of the parotid in an adult: an unusual case and a review of the literature

1997 ◽  
Vol 111 (6) ◽  
pp. 588-589 ◽  
Author(s):  
R. G. M. Hughes ◽  
J. Oates
Keyword(s):  
Parotid Gland ◽  
Unusual Case ◽  
First Year ◽  
Review Of The Literature ◽  
Capillary Haemangioma ◽  
Parotid Tumours ◽  
First Year Of Life

AbstractHaemangioma of the parotid gland is a well-described condition that accounts for 50 per cent of parotid tumours presenting during the first year of life. Parotid haemangiomas in adults are much rarer and until now only the cavernous variety have been reported. We report a case of a capillary haemangioma in an adult and discuss the literature.

Unusual case of aortic valve involvement in patient with Löffler’s Endomyocarditis: management, follow-up and short review of the literature

2007 ◽  
Vol 24 (3) ◽  
pp. 309-313 ◽  
Author(s):  
Evin Bozcali ◽  
Farid Aliyev ◽  
Mustafa Tarik Agac ◽  
Hakan Erkan ◽  
Barıs Okcun ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Unusual Case ◽  
Short Review ◽  
Review Of The Literature

An Unusual Case of Desmoplastic Melanoma With Monster Cells Imitating an Atypical Fibroxanthoma

2021 ◽  
pp. 106689692110447
Author(s):  
Juan J. Ríos-Martín ◽  
Manuel Pérez-Pérez ◽  
Sebastián Umbría-Jiménez ◽  
David Moreno-Ramírez ◽  
Ana Vallejo-Benítez
Keyword(s):  
Cyclin D1 ◽  
Copy Number ◽  
Poor Prognosis ◽  
Unusual Case ◽  
Prognostic Significance ◽  
Mutation Status ◽  
Atypical Fibroxanthoma ◽  
Desmoplastic Melanoma ◽  
Aggressive Tumor

Numerous cells with very large and irregular nuclei (“monster” cells) have not hitherto been reported in desmoplastic melanoma (DM). Their prognostic significance in melanomas is a matter of debate, although some authors have associated them with more aggressive tumor behavior. We report a mixed DM on the scalp of an 88-year-old woman imitating an atypical fibroxanthoma. Tumor cells stained positive for SOX10, S100, and cyclin D1; BRAF mutation status was negative, and fluorescence in situ hybridization analysis showed copy number gains in 11q13 (cyclin D1) and 6p25 (RREB1), and loss in 6q23 (MYB). Cyclin D1 amplification is associated with poor prognosis in melanoma.

Squamous Differentiation in a Sarcomatoid Chromophobe Renal Cell Carcinoma: An Unusual Case Report With Review of the Literature

2008 ◽  
Vol 132 (10) ◽  
pp. 1672-1674
Author(s):  
Seethalakshmi Viswanathan ◽  
Sangeeta B. Desai ◽  
S. R. Prabhu ◽  
Mahul B. Amin
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Unusual Case ◽  
Chromophobe Renal Cell Carcinoma ◽  
Rare Occurrence ◽  
Review Of The Literature ◽  
Squamous Differentiation ◽  
Unusual Case Report

Abstract We describe an extremely rare occurrence of a squamous differentiation in a sarcomatoid chromophobe renal cell carcinoma in a 45-year-old woman with nodal and lung metastasis at presentation. The tumor on histology showed all 3 components intimately admixed with each other, which to the best of our knowledge is the first such case to be reported in the literature. The renal pelvis was smooth walled and uninvolved. Kidney-specific cadherin was positive in the chromophobe renal cell carcinoma areas and negative in the sarcomatoid and squamous areas.

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