In-vitro Antioxidant and Antimicrobial activities of Murraya koiengii and Ficus palmata leaf extracts from North-western Himalayan Region

Plant based compounds are used as an alternate to chemically synthesized compounds in pharmaceutical industries. The main aim of the study was to evaluate the phytochemical, antioxidant and antimicrobial activities of leaf extract of two medicinal plants i.e. Murraya koiengii and Ficus palmata collected from north-western Himalayan region. The phytochemical screening of these plant extract showed the presence of alkaloids, phenols, tannins, flavonoids and the absence of terpenoids and saponins. The qualitative data analysis confirmed the highest level of phytochemicals in Murraya koiengii plant extract as compared to Ficus palmata. The antioxidant results show the dose dependent manner. The minimum inhibitory concentration (MIC) value of the extracts was found at concentration of 1.5625 mg/ml for Murraya koiengii and 3.125 mg/ml for Ficus palmata. The present study supports the use plant extracts as an alternative medicine in the ailment of many diseases.

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Antioxidant and Antimicrobial Activities of Pogostemon cablin (Blanco) Benth.

Journal of Botany ◽

10.1155/2017/8310275 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 4

Author(s):

Bhanuz Dechayont ◽

Pimnapa Ruamdee ◽

Sukrita Poonnaimuang ◽

Khwanchanok Mokmued ◽

Jitpisute Chunthorng-Orn

Keyword(s):

Plant Extract ◽

Antioxidant Activities ◽

Antibacterial Properties ◽

Ethanolic Extract ◽

Antimicrobial Activities ◽

Total Phenolic ◽

No Production ◽

Dependent Manner ◽

Pogostemon Cablin ◽

Antioxidant And Antimicrobial Activities

Pogostemon cablin (Lamiaceae) has been widely used in traditional medicine. In this study, the antioxidant and antimicrobial activities of leaves from P. cablin extracts were investigated. The water extracts had the highest total phenolic content 116.88±0.48 mg gallic acid equivalent/g of dry plant extract. Nevertheless, high levels of total flavonoid content were found in ethanolic extracts 280.12±2.04 mg quercetin equivalent/g of dry plant extract. The highest antioxidant activities were found for the ethanolic extract (IC50=18±0.90, 20±0.24 μg/mL) by DPPH and ABTS scavenging assays, respectively. Both extracts showed moderate inhibition of superoxide inhibition (O2∙-) and nitric oxide (NO) production in concentration-dependent manner. Antibacterial activity was calculated by disk diffusion, minimum inhibitory concentration (MIC), and minimum bacterial concentration (MBC). The ethanolic extract had the greatest activity against methicillin resistant Staphylococcus aureus, methicillin sensitive S. aureus, and Streptococcus pyogenes with zone diameters of 11.67±1.53, 10.33±2.52, and 10.33±1.15 mm, respectively. The corresponding MIC and MBCs were 5, 0.625, and 0.039 mg/mL. P. cablin extracts contain antioxidant and antibacterial properties that should be exploited for possible clinical application.

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Microwave Assisted One-Pot Green Synthesis of Silver Nanoparticles Using Leaf Extracts from Vigna Unguiculate: Evaluation of Antioxidant and Antimicrobial Activities

International Journal of Multidisciplinary Studies ◽

10.4038/ijms.v5i2.100 ◽

2018 ◽

Vol 5 (2) ◽

pp. 62

Author(s):

B. R. Perera ◽

M. Kandiah

Keyword(s):

Silver Nanoparticles ◽

Green Synthesis ◽

Antimicrobial Activities ◽

Leaf Extracts ◽

One Pot ◽

Microwave Assisted ◽

Antioxidant And Antimicrobial Activities

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Assessment of Antioxidant and Antimicrobial Activities of Silver Nanoparticles Biosynthesized by Haplophyllum Obtusifolium

Avicenna Journal of Medical Biochemistry ◽

10.34172/ajmb.2020.14 ◽

2020 ◽

Vol 8 (2) ◽

pp. 94-98

Author(s):

Mohammad Reza Rezaei ◽

Ali Es-haghi ◽

Parichehreh Yaghmaei ◽

Maryam Ghobeh

Keyword(s):

Antioxidant Activity ◽

Silver Nanoparticles ◽

Antimicrobial Agents ◽

Antioxidant Activities ◽

Antimicrobial Activities ◽

Dependent Manner ◽

Concentration Dependent Manner ◽

The North ◽

Chamber Temperature ◽

Pharmaceutical Industries

Background: Plants comprise great antioxidant sources as a result of their redox and biochemical components, which are rich in secondary metabolites such as phenolic acids, flavonoids, and other constituents. Haplophyllum obtusifolium from polygonaceae is widely used for preventing and managing diabetes. This study investigated the antibacterial and antioxidant activities of silver nanoparticles (AgNPs) biosynthesized by H. obtusifolium. Methods: The aerial parts of H. obtusifolium were gathered from the north of Khorasan Razavi province, Iran and desiccated at the chamber temperature. The shoots were powdered by grinding, 5 g of the powder was mixed with 250 mL of deionized water, and the resultant blend was then filtered. Bactericidal properties and antioxidant activity of the nanoparticles were assessed using disk diffusion and DPPH (2, 2-diphenyl-1-picrylhydrazyl) tests, respectively. Results: The results of this study showed that the biosynthesized nanoparticles exhibited antibacterial activity against a gram-negative (Klebsiella pneumoniae) bacterium, but they had no effects on gram-positive Staphylococcus epidermidis. Antioxidant test results showed that these nanoparticles were capable of eliminating DPPH radicals in a concentration-dependent manner so that a more potent antioxidant activity was seen in higher concentrations of the nanoparticles. Conclusion: Our results suggested that H. obtusifolium can be used as a key source of antioxidants/ antimicrobial agents in food and pharmaceutical industries.

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