scholarly journals Optical neurorretinitis by Bartonella Henselae - case report

2021 ◽  
Author(s):  
Raddib Eduardo Noleto da Nobrega Oliveira ◽  
Rafael Pereira Guimarães ◽  
Maria Eduarda Angelo de Mendonça Filleti ◽  
Thábata Emanuelle Martins Nunes
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Medical Records ◽  
Bartonella Henselae ◽  
Ocular Involvement ◽  
Cat Scratch Disease ◽  
Clinical Presentations ◽  
Patient Reported ◽  
Mucous Membranes ◽  
Parinaud’S Oculoglandular Syndrome

Introduction: Cat scratch disease is an infection caused by Bartonella henselae, usually transmitted to humans through cat scratch or bite. The most common clinical manifestation is lymphadenitis, but 5 to 10% of patients with cat scratch disease may have ocular involvement. Objectives and methodology: This work aims to report a case of Neuroretinitis optica by Bartonella Henselae. Data were collected through analysis of medical records with the patient’s consent. Results / Case report: Female, 22 years old, born in Joinville, presented, acutely, decreased visual acuity in RE, without pain on eye movement. She reported flu with fever in the previous month and denied recent vaccination. Visual acuity was 20/40 in RE and the fundus revealed papilla edema, hemorrhage and uveitis (+ / 4 +). In laboratory tests there were no changes. Serology for toxoplasmosis revealed a slight increase in IgM and the other serologies were negative. Sulfamethoxazole 800 mg / trimethoprim 160 mg started 12/12 hs and prednisone 80 mg / day, without improvement. Evolved with worsening and visual acuity (20/100) in OD. Retinography showed vascular narrowing, papillary blurring, decreased foveal brightness and macular edema, configuring optic neuritis D, with no changes in the LE. The neurological evaluation did not find any findings other than visual changes. The CSF study, cranial and orbit MRs were normal. At that time, the patient reported having had contact with a dead kitten. Serology was positive for Bartonella (IgM 1/100). Doxycycline 100mg started at 12 / 12h. After 15 days, a stellate macula and a slight improvement in papilla edema were observed. The patient evolved with full recovery. Conclusion: B.henselae is the main etiological agent of DAG. Kittens are the main reservoirs of B.henselae. Contact with mucous membranes or conjunctivae may be involved. Cat scratch disease (GAD) has two clinical presentations. Typical GAD is characterized by subacute regional lymphadenopathy; atypical GAD is the designation for numerous manifestations involving several organs, and occurs in 10- 15% of cases, being responsible for Parinaud’s oculoglandular syndrome.

Lyme disease atypically presenting with a singular symptom: Unilateral chorioretinitis

2020 ◽  
pp. 112067212096205
Author(s):  
Erol Havuz ◽  
Seda Güdül Havuz
Keyword(s):  
Visual Acuity ◽  
Lyme Disease ◽  
Retinal Vasculitis ◽  
Ocular Involvement ◽  
Ischemic Optic Neuropathy ◽  
Sudden Loss ◽  
Patient Reported ◽  
History Of ◽  
Verification Test ◽  
The Right

Background: Lyme disease, caused by Borrelia burgdorferi, is a spirochetal disease. Lyme disease-related ocular findings may also provide important clues. Ocular involvement is most commonly seen as uveitis, chorioretinitis, conjunctivitis, keratitis, episcleritis, papillitis, panuveitis, ischemic optic neuropathy, papilledema, and retinal vasculitis. Case: A 27-year-old male patient was admitted with a history of fatigue, malaise, and sudden loss of vision in his left eye for 3 days. The best visual acuity was found 20/20 in the right eye and 20/400 in the left eye. Fluorescein fundus angiography showed no pathological findings in the right eye; but hyperfluorescence that was compatible with choroiditis foci was seen in the left eye. Optical coherence tomography (OCT) showed choroidal thickening in the left eye compared to the right eye. Lyme IgM antibody was found to be positive, explaining choroiditis etiology, while IgG values were found to be negative. Western blot verification test was positive. The patient was treated with 2 × 100 mg doxycycline (21 days) with a diagnosis of Lyme disease, prednol 1 mg/kg/day (10 days) for choroiditis. Omeprazole tablets were given 1 × 1 during the period of cortisone intake. On the third day of treatment, visual acuity increased to 20/200 and continued to increase until reaching 20/20 in the second week. Conclusions: Lyme disease is rare, but must be kept in mind when investigating the etiology of chorioretinitis and retinal vasculitis. The patient reported here is, to our knowledge, the second case reported in literature that shows atypical clinic for Lyme disease with unilateral chorioretinitis without Erythema chronicum migrans (ECM).

Eritema nodoso: gatta ci cova

2021 ◽  
Vol 24 (10) ◽  
pp. 304-308
Author(s):  
Caterina Bacci ◽  
Sara Picariello ◽  
Francesco Vierucci ◽  
Carlo Mazzatenta ◽  
Angelina Vaccaro
Keyword(s):  
Clinical Manifestation ◽  
Erythema Nodosum ◽  
Bartonella Henselae ◽  
Diagnostic Evaluation ◽  
Cat Scratch Disease ◽  
Clinical Presentations ◽  
Atypical Manifestations ◽  
Systemic Symptoms ◽  
Atypical Manifestation ◽  
Subsequent Onset

Erythema nodosum is a panniculitis that can be triggered by many different stimuli. The paper describes the case of a child who presented with erythema nodosum as the unique clinical manifestation of cat scratch disease. Bartonella henselae infection usually presents with non-tender papule in the scratch line followed by subsequent onset of regional lymphadenopathy eventually associated with systemic symptoms. It can also present with atypical manifestation, such as erythema nodosum. The heterogeneity of the clinical presentations makes the disease to be underdiagnosed, whereby it is important to recognize atypical manifestations. Therefore, it is recommended to include Bartonella henselae serology in the diagnostic evaluation of erythema nodosum.

Cat-scratch disease: Otolaryngologic manifestations and management

2005 ◽  
Vol 132 (3) ◽  
pp. 353-358 ◽  
Author(s):  
Gerd Jürgen Ridder ◽  
Carsten Christof Boedeker ◽  
Katja Technau-Ihling ◽  
Anna Sander
Keyword(s):  
Head And Neck ◽  
Bartonella Henselae ◽  
Neck Region ◽  
Prospective Clinical Study ◽  
Cat Scratch Disease ◽  
Head And Neck Region ◽  
Lymph Node Enlargement ◽  
Parinaud’S Oculoglandular Syndrome ◽  
Common Manifestation ◽  
Atypical Manifestation

OBJECTIVE: The bacteria Bartonella henselae has been known as the principal causative agent of cat-scratch disease (CSD) since 1992. It is an important cause of infectious lymphadenopathies in the head and neck. Nevertheless, CSD often remains unrecognized in cases of cervicofacial lymph node enlargement. STUDY DESIGN: Between January 1997 and May 2003, we conducted a prospective clinical study including 721 patients with primarily unclear masses in the head and neck. RESULTS: CSD was diagnosed by serology and molecular investigations in 99 patients (13.7%; median age 33 years). Cervicofacial lymphadenopathy was the most common manifestation. Atypical manifestation of CSD including Parinaud's oculoglandular syndrome, swelling of the parotid gland and erythema nodosum were diagnosed in 8.1%, 8.1%, and 2.0% of cases, respectively. CONCLUSIONS: Our results demonstrate that CSD is a major cause of enlarged cervicofacial lymph nodes and should therefore be included in the differential diagnosis of lymphadenopathy in the head and neck region.

scholarly journals What Is in a Cat Scratch? Growth of Bartonella henselae in a Biofilm

2021 ◽  
Vol 9 (4) ◽  
pp. 835
Author(s):  
Udoka Okaro ◽  
Sierra George ◽  
Burt Anderson
Keyword(s):  
Biofilm Formation ◽  
Current Knowledge ◽  
Bartonella Henselae ◽  
Biological Significance ◽  
Mammalian Host ◽  
Cat Scratch Disease ◽  
Cat Flea ◽  
Clinical Presentations

Bartonella henselae (B. henselae) is a gram-negative bacterium that causes cat scratch disease, bacteremia, and endocarditis, as well as other clinical presentations. B. henselae has been shown to form a biofilm in vitro that likely plays a role in the establishment and persistence of the bacterium in the host. Biofilms are also known to form in the cat flea vector; hence, the ability of this bacterium to form a biofilm has broad biological significance. The release of B. henselae from a biofilm niche appears to be important in disease persistence and relapse in the vertebrate host but also in transmission by the cat flea vector. It has been shown that the BadA adhesin of B. henselae is critical for adherence and biofilm formation. Thus, the upregulation of badA is important in initiating biofilm formation, and down-regulation is important in the release of the bacterium from the biofilm. We summarize the current knowledge of biofilm formation in Bartonella species and the role of BadA in biofilm formation. We discuss the evidence that defines possible mechanisms for the regulation of the genes required for biofilm formation. We further describe the regulation of those genes in the conditions that mimic both the arthropod vector and the mammalian host for B. henselae. The treatment for persistent B. henselae infection remains a challenge; hence, a better understanding of the mechanisms by which this bacterium persists in its host is critical to inform future efforts to develop drugs to treat such infections.

scholarly journals An Atypical Case of Bartonella henselae Osteomyelitis and Hepatic Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Dionna M. Mathews ◽  
Katie M. Vance ◽  
Pamela M. McMahon ◽  
Catherine Boston ◽  
Michael T. Bolton
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Bartonella Henselae ◽  
Hepatic Disease ◽  
Cat Scratch Disease ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Atypical Case ◽  
Hepatic Lesions ◽  
Atypical Presentations

Bartonella henselae is a Gram-negative bacterium and the causative agent of cat scratch disease (CSD). Atypical presentations of B. henselae that involve the musculoskeletal, hepatosplenic, cardiac, or neurologic systems are rare. In this case report, we describe a case of B. henselae osteomyelitis involving bilateral iliac bones complicated by hepatic lesions in a 12-year-old immunocompetent female patient. Although B. henselae is a rare cause of osteomyelitis, it should be considered when patients who present with fever, pain, and lymphadenopathy do not respond to routine osteomyelitis therapy.

scholarly journals Cat Scratch Disease: The First Case Report in Republic of North Macedonia

PRILOZI ◽  
2020 ◽  
Vol 41 (3) ◽  
pp. 71-75
Author(s):  
Kostadin Poposki ◽  
Zaklina Sopova ◽  
Marija Dimzova ◽  
Elena Denkovska ◽  
Tatjana Stoleska ◽  
...  
Keyword(s):  
Case Report ◽  
Day Treatment ◽  
Bartonella Henselae ◽  
Complete Recovery ◽  
Cat Scratch Disease ◽  
First Case ◽  
History Of ◽  
Disease Specialist ◽  
Adult Female Patient ◽  
Main Clinical Manifestation

AbstractCat scratch disease (CSD) is the main clinical manifestation caused by Bartonella henselae in immuno-competent patients. The bacterium is transmitted to humans from cats via scratches or bites. In this case report, we are presenting to our knowledge the first etiologically confirmed case of CSD in our country. Here we describe the case of a previously healthy adult female patient presenting with fever and axillar lymphadenopathy over 1-month period. She underwent numerous clinical and paraclinical investigations for potential etiologies associated with lymphadenopathy and fever. Finally, serological testing for B.henselae was performed with titers for IgG 1:1024 and 1:160 for IgM, which confirmed the diagnosis. Five-day treatment with azithromycin resulted with good clinical response and complete recovery. We proved that CSD is a reality in our country and this report should raise awareness in medical doctors, especially infectious disease specialist. Also, CSD should be included in differential diagnosis in patients with fever of unkown origin (FUO), who are presenting with regional lymphadenopathy, with or without history of cat contact.

scholarly journals Parinaud syndrome caused by Bartonella henselae: case report

1996 ◽  
Vol 38 (6) ◽  
pp. 437-440 ◽  
Author(s):  
Carlos Alberto Yamashita ◽  
Adriana Mielle ◽  
Natasha Slhessarenko ◽  
Sérgio Nascimento ◽  
Alfredo Gilio ◽  
...  
Keyword(s):  
Case Report ◽  
Indirect Immunofluorescence ◽  
Bartonella Henselae ◽  
Etiologic Agent ◽  
Cat Scratch Disease ◽  
Surgical Interventions

The authors report a case of Parinaud syndrome (conjunctivitis with pre-auricular satellite adenitis) caused by Bartonella henselae, the etiologic agent of Cat Scratch Disease. The etiologic assessment of this case was performed by serum indirect immunofluorescence reaction and allowed for a better therapeutics and follow up, avoiding ineffective antibiotics and surgical interventions.

scholarly journals Beyond Cat Scratch Disease: A Case Report ofBartonellaInfection Mimicking Vasculitic Disorder

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Amelia Spinella ◽  
Federica Lumetti ◽  
Gilda Sandri ◽  
Valentina Cestelli ◽  
Maria Teresa Mascia
Keyword(s):  
Case Report ◽  
Lymph Nodes ◽  
Bartonella Henselae ◽  
Skin Lesions ◽  
Bacterial Disease ◽  
Cat Scratch Disease ◽  
History Of ◽  
Vasculitic Disorder

Cat scratch disease (CSD) is a bacterial disease caused byBartonella henselaeand it is mainly characterized by self-limiting lymphadenopathy in the draining site of a cat scratch or bite. We report a patient with history of fever, swelling lymph nodes, vasculitic-like skin lesions, and positivity ofBartonellaserology initially considered as expression of a disimmune disease.

Sign in / Sign up

Export Citation Format

Share Document