Frequency of Left Plueral Effusion in Acute Necrotizing Pancreatitis

2021 ◽  
Vol 15 (10) ◽  
pp. 3349-3351
Author(s):  
Hunain . ◽  
Farah Saleem ◽  
Muhammad Waqas Arshad ◽  
Kauser Shaikh ◽  
Mamoona Shaikh ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Pleural Effusion ◽  
Serum Amylase ◽  
Necrotizing Pancreatitis ◽  
Case Series ◽  
Acute Necrotizing Pancreatitis ◽  
Amylase Level ◽  
X Ray ◽  
Left Pleural Effusion ◽  
Acute Necrotizing

Objective: The aim of this study is to calculate the prevalence of left plueral effusion in acute necrotizing pancreatitis. Study Design: Observational/ case series Place and Duration: Conducted at surgery department of Saidu Teaching Hospital, Swat and Ibne Sina Hospital and Research Institute, Multan for duration of six months from January 2021 to June 2021. Methods: A total of 95 patients, both males and females, ranging in age from 15 to 65 years, were presented. After receiving informed written consent, the baseline comprehensive demographics of the patients presented were recorded, including age, gender, and body mass index. Patients with acute pancreatitis and serum amylase levels greater than 300U/dL were eligible to participate. Patients were subjected to X-ray and CT scans in their entirety. Prevalence of necrotizing pancreatitis was calculated by CT scan and for left plueral effusion X-ray of chest was taken. SPSS 24.0 version was used to analyze complete data. Results: Majority of the patients 65 (68.4%) were females and 30 (31.6%) were males with mean age 39.14+5.67 years. 26 (27.4%) cases had BMI less than 20kg/m2 and the majority were >20kg/m2. Gallstone was the most common cause of acute pancreatitis found in 45 (47.4%) cases, followed by alcoholism 25 (26.3%) and medications 12 (12.6%). Among 95 cases, prevalence of necrotizing pancreatitis was 42 (44.2%) in which 40 cases had left plueral effusion. Mortality rate among necrotizing pancreatitis was 13 (33.3%). Conclusion: We found that the majority of individuals with necrotizing pancreatitis experienced pleural effusion on the left side. Thus, patients with acute pancreatitis who have a high serum amylase level must be treated earlier if they have a left pleural effusion because of severity. Keywords: Plueral Effusion, Acute Necrotizing Pancreatitis, Mortality

The burden of acute pancreatitis and early experience of step-up approach for acute necrotizing pancreatitis at Military Hospital

2019 ◽  
Vol 22 (2) ◽  
pp. 11-17
Author(s):  
Sushil Bahadur Rawal ◽  
Uttam Laudari ◽  
Basanta Khatiwada ◽  
Anup Thapa ◽  
Manoj Kumar Jha ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Necrotizing Pancreatitis ◽  
Early Experience ◽  
Acute Necrotizing Pancreatitis ◽  
Military Hospital ◽  
Army Hospital ◽  
Acute Necrotizing ◽  
Hospital Resources ◽  
Open Necrosectomy

Introduction: Twenty-five percent of acute pancreatitis develops severe acute pancreatitis (SAP). SAP patients have prolonged hospitalization and require a substantial amount of manpower and hospital resources. The aim of this study was to give an insight into the burden of acute pancreatitis at a tertiary level military hospital and to share the experience of managing pancreatic necrosis with the application of the step-up approach. Methods: A prospective descriptive study of consecutive patients was conducted at Shree Birendra Army Hospital from 2017 June to 2017 November. Patients with a diagnosis of acute pancreatitis admitted were stratified according to severity as per Revised Atlanta classification 2012. Patients with acute necrotizing pancreatitis were enrolled for the step-up approach. Patient’s demography, baseline investigations, radiology, prognostic scoring scales and type of intervention were analyzed. The burden of severe acute pancreatitis at our center and the early experience of the step-up approach at our centre within the study period were studied. Results: Out of 35 five patients with acute pancreatitis, 7 (20%) subsequently developed severe acute pancreatitis. Among them, five patients subsequently developed necrotizing pancreatitis who were managed according to the step-up approach. Out of them, three patients subsequently underwent operative intervention in the form of minimally invasive procedures like percutaneous drain placement, laparoscopic necrosectomy, video-assisted retroperitoneal debridement, and open necrosectomy. Conclusion: Acute pancreatitis is a common presentation at our centre. The step-up approach in the management of acute necrotizing pancreatitis is a safe and feasible approach.

scholarly journals COVID-19 Associated Acute Necrotizing Pancreatitis with Normal Serum Amylase and Lipase Levels: Report of an Unusual Finding

2021 ◽  
Vol 36 (5) ◽  
pp. e304-e304
Author(s):  
Hemanth Sudarsanam ◽  
Dillibabu Ethiraj ◽  
Navaneetha Kumar Govarthanan ◽  
Srinivasan Kalyanasundaram ◽  
Sathya Arunachalam Chitra ◽  
...  
Keyword(s):  
Serum Amylase ◽  
Necrotizing Pancreatitis ◽  
Large Family ◽  
Acute Onset ◽  
Normal Serum ◽  
Acute Necrotizing Pancreatitis ◽  
Host Cells ◽  
Biliary Stones ◽  
Gastrointestinal Complications ◽  
Acute Necrotizing

Coronaviruses are a large family of single-stranded RNA viruses infecting humans and animals, causing a multitude of symptoms. COVID-19 is not only known to affect the respiratory system, but shows unusual gastrointestinal complications. Pancreatitis can be caused by biliary stones, alcohol abuse, viruses, drug intake, metabolic syndromes, or trauma. Diagnosis of acute pancreatitis requires any two of the three criteria: acute onset of severe upper abdominal pain, consistent with pancreatitis; elevation of serum amylase or lipase, three times the upper limit of normal; and/or characteristic imaging findings. COVID-19 associated pancreatitis is thought to be mediated by the angiotensin-converting enzyme-2 receptor on the host cells, which are highly expressed in the pancreatic cells. Here, we report a unique case of acute necrotizing pancreatitis caused by COVID-19 with hyperglycemia and normal amylase and lipase levels.

scholarly journals COVID-19 Presenting as Acute Necrotizing Pancreatitis

2021 ◽  
Vol 9 ◽  
pp. 232470962110093
Author(s):  
Mohammad Mohammadi Arbati ◽  
Mohammad Hadi Molseghi
Keyword(s):  
Acute Pancreatitis ◽  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Acute Abdomen ◽  
Necrotizing Pancreatitis ◽  
Acute Necrotizing Pancreatitis ◽  
Differential Diagnoses ◽  
The Novel ◽  
Acute Necrotizing ◽  
Novel Coronavirus

The ongoing pandemic of the novel coronavirus disease 2019 (COVID-19) originated in Wuhan, China, in December 2019. Various manifestations of coronavirus (SARS-CoV-2 [severe acute respiratory syndrome coronavirus 2]) have been reported since the pandemic began. Some articles have reported acute pancreatitis in several patients due to COVID-19 infection. In this case report, we introduce a patient in whom SARS-CoV-2 caused necrotizing pancreatitis. Acute abdomen is one of the manifestations of COVID-19. Various causes such as acute pancreatitis and necrotizing pancreatitis can be in the list of differential diagnoses.

scholarly journals Risk Factors For Development Of Acute Necrotizing Pancreatitis

2015 ◽  
Vol 16 (2) ◽  
pp. 121-127
Author(s):  
Bojan Stojanovic ◽  
Marko Spasic ◽  
Ivan Radosavljevic ◽  
Dragan Canovic ◽  
Dragce Radovanovic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Pancreatitis ◽  
Initial Treatment ◽  
Positive Impact ◽  
Necrotizing Pancreatitis ◽  
Acute Necrotizing Pancreatitis ◽  
Surgical Intensive Care Unit ◽  
High Morbidity ◽  
Surgical Intensive Care ◽  
Acute Necrotizing

Abstract Acute necrotizing pancreatitis (ANP) is a severe form of acute pancreatitis that is associated with high morbidity and mortality. Thus, an adequate initial treatment of patients who present with acute pancreatitis (AP) based on correct interpretation of early detected laboratory and clinical abnormalities may have a significant positive impact on the disease course. The aim of the study was to determine patient- and initial treatment-related risk factors for the development of acute necrotizing pancreatitis. For the purpose of this study a case-control design was chosen, including adult patients treated for AP in the surgical Intensive Care Unit (sICU) of Clinical Center of Kragujevac, from January 2006 to January 2011. The cases (n=63) were patients who developed ANP, while the controls (n=63) were patients with AP without the presence of pancreatic necrosis. The controls were randomly selected from a study sample after matching with the cases by age and sex. Significant association with the development of ANP was found for the presence of comorbidity (adjusted OR 6.614 95%CI 1.185-36.963), and the use of somatostatin (adjusted OR 7.460, 95%CI 1.162-47.833) and furosemide (adjusted OR 2710.57, 95%CI 1.996-56.035) started immediately upon admission to the sICU. This study suggests that comorbidities, particularly the presence of serious cardio-vascular disease, can increase the risk for development of acute necrotizing pancreatitis. The probability for the development of ANP could be reduced by the avoidance of the initial use of loop diuretics and somatostatin.

scholarly journals Management of Acute Necrotizing Pancreatitis through Ayurveda Regimen: A Case Report

2019 ◽  
Vol 7 (02) ◽  
Author(s):  
Sonia Gupta
Keyword(s):  
Acute Pancreatitis ◽  
Necrotizing Pancreatitis ◽  
Treatment Strategies ◽  
Modern Science ◽  
Pancreatic Tissue ◽  
Acute Necrotizing Pancreatitis ◽  
Science Management ◽  
Progression Of Disease ◽  
Acute Necrotizing ◽  
Cardinal Symptoms

Necrotizing pancreatitis is an extreme complication of acute pancreatitis. Acute pancreatitis is an inflammation of the pancreas. Pancreas sits behind the stomach. One of its main functionsis to make enzymes that help in digest the food. Normally, those enzymes flow through a small opening into small intestines. If pancreas becomes inflamed, the enzymes can start to leak into parts of the pancreas instead. These enzymes can sometimes kill pancreatic tissue, resulting in necrotizing pancreatitis. The dead tissue can get infected and cause life-threatening complications. Cardinal symptoms are abdominal pain (boring nature), nausea, vomiting, and tenderness in abdomen, pain worsened after eating, steatorrhea and weight loss. Assessments were made using Elevated levels of Serum Amylase and Lipase. In modern science, management is Lifelong enzymes, Periodical Emergency hospitalisation, IV fluids, painkillers, anti-inflammatory, andantibiotics, ERCP stunting, surgical intervention. It involves high cost, side effects and in many cases, there is progression of disease leading to fear, frustration and debility among sufferers. In Ayurveda three doshas are described as Vata, Pitta, Kapha.  Pitta dosha we have substances exactly similar to enzymes. The features of acute pancreatitis are similar to the features of pitta where tikshna and ushna guna of pitta are aggravated. The observations reveal that, Ayurvedic regimen can play a key role in the management of conditions like pancreatitis. A 25years old male patient diagnosed with acute necrotizing pancreatitis. At the end of the treatment, there was considerable improvement in the subjective and objective criterias. The treatment strategies followed in this study can be safely adopted under the supervision of competent specialist.

scholarly journals Surgery Management of Pancreatitis with Complication: A Review Article

2022 ◽  
Vol 6 (1) ◽  
pp. 01-03
Author(s):  
Nanda Rachmad Putra Gofur ◽  
Aisyah Rachmadani Putri Gofur ◽  
Soesilaningtyas Soesilaningtyas ◽  
Rizki Nur Rachman Putra Gofur ◽  
Mega Kahdina ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Necrotizing Pancreatitis ◽  
Clinical Manifestations ◽  
Healing Time ◽  
Acute Necrotizing Pancreatitis ◽  
Close Monitoring ◽  
Necrotic Tissue ◽  
Acute Necrotizing ◽  
Walled Off Necrosis

Introduction: Acute pancreatitis is an inflammatory disease of the pancreas with clinical manifestations that vary from mild to severe manifestations to death. The incidence of pancreatitis varies in various countries in the world and depends on the cause such as alcohol, gallstones, and metabolic factors. The clinical picture and the main symptom in patients with acute pancreatitis is abdominal pain. Abdominal pain varies from mild to severe and excruciating. Abdominal pain that is felt is constant and dull, and is usually felt in the epigastrium and periumbilicus and often spreads to the back, chest, waist, and lower abdomen. Discussion: The onset of acute pancreatitis, the patient should be evaluated for hemodynamic status immediately and receive the necessary resuscitation measures. Patients with acute pancreatitis should receive aggressive intravenous rehydration (250 - 500 ml/hour with isotonic crystalloid fluid) as early as possible with close monitoring, unless contraindicated with cardiovascular and/or renal comorbidities. It is most effective within the first 12-24 hours, but after that the benefits may diminish. Debridement (necrosectomy) is the gold standard in infected acute necrotizing pancreatitis and peripancreatic necrosis. Indications for intervention either through radiological, endoscopic or surgical procedures in necrotizing pancreatitis are suspected or proven infected necrotizing pancreatitis with clinical deterioration, especially after the necrotic tissue has been encapsulated with thick walls (walled-off necrosis). Sterile necrotizing pancreatitis with persistent organ failure several weeks after the onset of acute pancreatitis, particularly after the necrotic tissue has been encapsulated with thick walls (walled-off necrosis). Conclusion: Surgical management is often used in pancreatitis associated with gallstones. Cholecystectomy within 48 hours of the complaint can increase healing time. In addition, cholecystectomy performed early may not increase the risk of complications secondary to surgery. Surgery is not performed in acute necrotizing pancreatitis until the inflammation is reduced and the fluid accumulation no longer increases in size.

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