scholarly journals What Is the Place of Intersphincteric Resection When Operating on Low Rectal Cancer?

ISRN Surgery ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Satoshi Nagayama ◽  
Waheeb Al-Kubati ◽  
Yoshiharu Sakai
Keyword(s):  
Rectal Cancer ◽  
Functional Outcomes ◽  
Recent Literature ◽  
Coloanal Anastomosis ◽  
Preoperative Chemoradiotherapy ◽  
Abdominoperineal Excision ◽  
Intersphincteric Resection ◽  
Low Rectal Cancer ◽  
Rectal Cancers

Operating on low rectal cancer by performing an intersphincteric resection (ISR) with coloanal anastomosis has been adopted as an alternative to abdominoperineal excision (APE) following Schiessel et al. report in 1994, as it preserves the sphincter and avoids the need for a permanent stoma. We undertook a review of the recent literature specifically focusing on long-term oncologic and functional outcomes of ISR to evaluate whether this operation is a valid alternative to an APE. In conclusion, younger patients with T1 or T2 rectal cancers who require no preoperative therapy are ideal candidates for ISR, given that preoperative chemoradiotherapy may cause long-term severe anal dysfunction after ISR.

scholarly journals Survival and functional and oncological outcomes following intersphincteric resection for low rectal cancer: short-term results

2018 ◽  
Vol 46 (4) ◽  
pp. 1617-1625 ◽  
Author(s):  
Călin Molnar ◽  
Butiurca Vlad-Olimpiu ◽  
Botoncea Marian ◽  
Togănel Cornelia ◽  
Gurzu Simona
Keyword(s):  
Rectal Cancer ◽  
Survival Rate ◽  
Functional Outcomes ◽  
Intersphincteric Resection ◽  
Low Rectal Cancer ◽  
Study Patient ◽  
Reference Ranges ◽  
Short Term ◽  
Wexner Score ◽  
Oncological Outcomes

Objective This study was performed to evaluate the 1-year survival rate and functional outcomes of 20 patients who underwent intersphincteric resection (ISR) for low rectal cancer. Methods Twenty patients who underwent ISR for low rectal cancer were followed up for 1 year. Complications, functional outcomes objectified by the Wexner score, and oncological outcomes were assessed. Results The short-term survival rate was 100%. The median Wexner score was ≤10 in all patients at 12 months after surgery. Signs of local recurrence were absent, and antigen levels remained within the reference ranges 1 year postoperatively. Conclusions ISR is a feasible alternative in highly selected patients who primarily refuse a colostomy bag and present with type II or III tumors. In the present study, patient-reported continence was satisfactory, and the absence of a colostomy bag increased patients’ quality of life. The oncological outcomes were satisfactory at 1 year postoperatively.

scholarly journals Intersphincteric Resection and Coloanal Anastomosis in Treatment of Distal Rectal Cancer

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Gokhan Cipe ◽  
Mahmut Muslumanoglu ◽  
Erkan Yardimci ◽  
Naim Memmi ◽  
Erhan Aysan
Keyword(s):  
Rectal Cancer ◽  
Abdominoperineal Resection ◽  
Functional Outcomes ◽  
Coloanal Anastomosis ◽  
Intersphincteric Resection ◽  
Distal Rectal Cancer ◽  
Sphincter Saving ◽  
Resection Line ◽  
Alternative Choice

In the treatment of distal rectal cancer, abdominoperineal resection is traditionally performed. However, the recognition of shorter safe distal resection line, intersphincteric resection technique has given a chance of sphincter-saving surgery for patients with distal rectal cancer during last two decades and still is being performed as an alternative choice of abdominoperineal resection. The first aim of this study is to assess the morbidity, mortality, oncological, and functional outcomes of intersphincteric resection. The second aim is to compare outcomes of patients who underwent intersphincteric resection with the outcomes of patients who underwent abdominoperineal resection.

Comparison of long-term survival outcomes between laparoscopic and open surgery for mid or low rectal cancer treated with preoperative chemoradiotherapy: 7-year follow-up of COREAN trial.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 3518-3518
Author(s):  
Ji Won Park ◽  
Seung-Yong Jeong ◽  
Sung-Bum Kang ◽  
Jungnam Joo ◽  
Mi Kyung Song ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Laparoscopic Surgery ◽  
Local Recurrence ◽  
Open Surgery ◽  
Disease Free Survival ◽  
Preoperative Chemoradiotherapy ◽  
Low Rectal Cancer ◽  
Free Survival ◽  
Disease Free

3518 Background: Laparoscopic surgery for rectal cancer has been used widely. However, recent two randomized trials raised concerns about short-term oncologic safety of laparoscopic surgery for rectal cancer. The aim of this study was to evaluate the long-term oncologic safety of laparoscopic surgery for rectal cancer based on 7-year data from the Comparison of Open versus laparoscopic surgery for mid or low REctal cancer After Neoadjuvant chemoradiotherapy (COREAN) trial. Methods: COREAN trial was a non-inferiority, randomized controlled trial. Between April, 2006, and Aug, 2009, eligible participants with mid or low rectal cancer treated with preoperative chemoradiotherapy were randomly assigned (1:1) to laparoscopic (n = 170) or open surgery (n = 170). Seven-year outcomes included overall and disease-free survival, and local recurrence. Log-rank test and stratified Cox regression analysis were used for survival analysis. Analysis was by intention to treat. Results: The median follow-up times were 84 months (IQR: 61.5-97.0). No differences were found between laparoscopic and open surgery group in terms of overall and disease-free survival, and local recurrence (7-year overall survival: 83.2% [laparoscopic] vs 77.3% [open], p = 0.48; 7-year disease-free survival: 71.6% [laparoscopic] vs 64.3% [open], p = 0.20; 7-year local recurrence: 3.3% [laparoscopic] vs 7.9% [open], p = 0.08). Stratified Cox regression analysis adjusted for ypT, ypN and tumor regression grade showed no significant difference between groups in terms of overall and disease-free survival, and local recurrence. The hazard ratios for overall survival, disease-free survival and local recurrence (open vs laparoscopic surgery) were 0.96 (95% CI = 0.58-1.57), 1.03 (95% CI = 0.70-1.53), and 2.28 (95% CI = 0.82-7.16), respectively. Conclusions: The 7-year analysis confirm the long-term oncological safety of laparoscopic surgery for rectal cancer treated with preoperative chemoradiotherapy. The use of laparoscopic surgery does not compromise the long-term survival outcomes in rectal cancer. Clinical trial information: NCT00470951.

Comparison of Functional Results and Quality of Life Between Intersphincteric Resection and Conventional Coloanal Anastomosis for Low Rectal Cancer

2004 ◽  
Vol 47 (6) ◽  
pp. 832-838 ◽  
Author(s):  
Frédéric Bretagnol ◽  
Eric Rullier ◽  
Christophe Laurent ◽  
Frank Zerbib ◽  
Renaud Gontier ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Coloanal Anastomosis ◽  
Functional Results ◽  
Intersphincteric Resection ◽  
Low Rectal Cancer
Sign in / Sign up

Export Citation Format

Share Document