scholarly journals Persistent Atrial Fibrillation Is Associated with Worse Prognosis Than Paroxysmal Atrial Fibrillation in Acute Cerebral Infarction

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Halvor Naess ◽  
Ulrike Waje-Andreassen ◽  
Lars Thomassen

Background and Purpose. We hypothesized that patients with persistent atrial fibrillation (AF) suffer from more severe cerebral infarction than patients with paroxysmal AF due to differences in clot structure and volume. Methods. This study includes consecutive patients with acute cerebral infarction and persistent or paroxysmal AF documented by ECG any time prior to stroke onset. The National Institute of Health Stroke Scale (NIHSS) was used to assess stroke severity on admission. Short-term outcome was determined by the modified Rankin scale (mRS) score, Barthel index, and NIHSS score 7 days after stroke onset. Risk factors were registered on admission. Eligible patients were treated with thrombolysis. Results. In total, 141 (52%) patients had paroxysmal AF, and 129 (48%) patients had persistent AF. NIHSS score on admission, mRS score at day 7, and mortality were significantly higher among patients with persistent AF. Thrombolysis was less effective in patients with persistent AF. Conclusions. Our study shows that patients with persistent AF and acute cerebral infarction have poorer short-term outcome than patients with paroxysmal AF. Differences in clot structure or clot volume may explain this.

2011 ◽  
Vol 34 (4) ◽  
pp. 249 ◽  
Author(s):  
Yanbo Peng ◽  
Dali Wang ◽  
Jiang Zhang ◽  
Xinhong Xue ◽  
Zhuo Wang ◽  
...  

Purpose: We studied the association between admission white blood cell (WBC) count and short term outcome in patients with acute cerebral infarction. Methods: 2808 patients with acute cerebral infarction were included in the study. WBC count and other variables were collected within the first 24 hours of admission. Clinical outcomes (death or dependency) were evaluated by neurologists during hospitalization. The associations between WBC count and in-hospital death or dependency at discharge were analyzed using a multiple logistic model. Result: Multivariate-adjusted odds ratio (95% confidence intervals) of dependency associated with patients with WBC of 10.0-10.9×109/L, 11.0-11.9×109/L, ≥12.0×109/L were 1.46(0. 87-2. 45), 6.21(3. 70-10. 42) and 7.01(4. 53-10. 87), respectively, when compared with patients with admission WBC counts < 10.0x109/L. Multivariate-adjusted odds ratio (95% confidence intervals) of death associated with WBC 10.0-10.9×109/L, 11.0-11.9×109/L and ≥12.0×109/L were 2.098(0. 96-4. 58), 4.79(2. 24-10. 22) and 5.59(3. 14-9. 98), respectively. Conclusion: Increased WBC count at admission was significantly and positively associated with in-hospital death or dependency at discharge among patients with acute cerebral infarction.


2009 ◽  
Vol 28 (1) ◽  
pp. 8-12 ◽  
Author(s):  
Halvor Naess ◽  
Jan Brogger ◽  
Ulrike Waje-Andreassen ◽  
Titto T. Idicula ◽  
Lars Thomassen

Stroke ◽  
2002 ◽  
Vol 33 (8) ◽  
pp. 2105-2108 ◽  
Author(s):  
H. Naess ◽  
H.I. Nyland ◽  
L. Thomassen ◽  
J. Aarseth ◽  
G. Nyland ◽  
...  

2002 ◽  
Vol 39 ◽  
pp. 127 ◽  
Author(s):  
Francis E. Marchlinski ◽  
David J. Callans ◽  
Erica S. Zado ◽  
Andrea J. Russo ◽  
Edward P. Gerstenfeld ◽  
...  

2012 ◽  
Vol 19 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Hasan Ari ◽  
Muhammet Gürdogan ◽  
Ercan Erdogan ◽  
Selma Ari ◽  
Yusuf Ata ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Antonino Sant'Angelo ◽  
Sergio Bagnato ◽  
Cristina Boccagni ◽  
Vincenzo Guardabasso ◽  
Giuseppe Galardi

Background. Patients with cardioembolic stroke due to atrial fibrillation (CE/AF stroke) seem to have a poorer functional recovery than those with non cardioembolic stroke. This may be ascribed to the heterogeneity between the samples of patients with and without CE/AF stroke. Aim. To compare the short-term outcome of patients with CE/AF stroke and with non-CE/AF stroke of same gender and similar age and level of disability and comorbidity. Methods. The functional independence measure (FIM) of 40 consecutive patients with CE/AF stroke was retrospectively evaluated at admission and discharge in our rehabilitation department. Each “case” was matched with a patient (“control”) of the same sex and similar age and FIM score at admission, affected by non-CE/AF stroke admitted to our department in the same period. Results. FIM score at admission and discharge was respectively and in patients with CE/AF stroke and and in patients with non-CE/AF stroke; no significant difference was found between the groups. Multivariate analysis showed an effect of the rehabilitation treatment and age on FIM score, whereas no effect was attributable to AF. Conclusions. The short-term outcome is similar in patients with and without CE/AF stroke.


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