Short communication: Use of a new form of protected sodium butyrate to control Salmonella infection in fattening pigs

A field trial on a commercial pig farm was carried out to assess the efficacy of the addition in the diet of fattening pigs of a new form of sodium butyrate protected with a sodium salt of coconut fatty acid distillate (3 kg/ton of feed) to control Salmonella spp. infection. Around 50 pigs were assigned to treatment group and 50 kept as controls. During the fattening period pigs were monthly sampled (serum and feces), and after slaughter fecal and mesenteric lymph nodes samples were collected. No differences in the proportion of shedders were observed between the sodium butyrate and the control groups, but a significant reduction in the number of infected pigs (61% vs. 4%; p<0.01) and in the median ELISA Optical Density percentage values (55.9% vs. 19.4%; p<0.01) at slaughter was observed in pigs under treatment compared to the controls. In addition, an overall significant association between seropositivity and Salmonella shedding and infection was detected. Results from this study add more evidences on the positive effect of butyrate on the control of pig salmonellosis.

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Salmonella spp. in Healthy Swine and in Abattoir Environments in Brazil

Journal of Food Protection ◽

10.4315/0362-028x-60.9.1029 ◽

1997 ◽

Vol 60 (9) ◽

pp. 1029-1033 ◽

Cited By ~ 11

Author(s):

NORMA S. LÁZARO ◽

ANITA TIBANA ◽

ERNESTO HOFER

Keyword(s):

Lymph Nodes ◽

Environmental Samples ◽

The Other ◽

Mesenteric Lymph Nodes ◽

Salmonella Spp ◽

Mesenteric Lymph ◽

Hygienic Measures ◽

And Storage ◽

Tank Water

Tonsils and inguinal, mesenteric, and prescapular lymph node samples collected from 115 swine carcasses from two abattoirs and a family-run operation in the State of Rio de Janeiro, Brazil, were cultured for the presence of Salmonella species. Salmonella spp. were detected in 40 (34.8%) of the swine samples with the following distribution; tonsils (31/40, 77.5%), mesenteric lymph nodes (16/40, 40.0%), inguinal lymph nodes, (9/40, 22.5%), and prescapular lymph nodes (7/40, 17.5%), Scalding tank water and environmental swabs collected from the abattoirs were also analyzed. Salmonella spp. were recovered from 13 of 51 (22.5%) of the environmental samples from one of the two abattoirs, none from those from the other abattoir. Salmonella spp. were recovered from the evisceration tables (5/11, 45.5%), the killing room (3/10, 30.0%), the holding pen (2/10, 20.0%), the butchering saw (2/10, 20.0%), and the scalding tank (1/10, 10.0%). The most frequently detected serovar was Salmonella Muenster. The results show the necessity of adopting more effective hygienic measures in the abattoirs as well as in the areas where swine are raised in order to reduce the role of abattoirs and storage facilities in the spread of Salmonella contamination.

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Sensitivity of the ISO 6579:2002/Amd 1:2007 Standard Method for Detection of Salmonella spp. on Mesenteric Lymph Nodes from Slaughter Pigs

Journal of Clinical Microbiology ◽

10.1128/jcm.02099-12 ◽

2012 ◽

Vol 51 (1) ◽

pp. 89-94 ◽

Cited By ~ 18

Author(s):

R. C. Mainar-Jaime ◽

S. Andrés ◽

J. P. Vico ◽

B. San Román ◽

V. Garrido ◽

...

Keyword(s):

Lymph Nodes ◽

Standard Method ◽

Mesenteric Lymph Nodes ◽

Salmonella Spp ◽

Mesenteric Lymph ◽

Slaughter Pigs

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Intestinal lesions in pigs affected with postweaning multisystemic wasting syndrome

Pesquisa Veterinária Brasileira ◽

10.1590/s0100-736x2008000600009 ◽

2008 ◽

Vol 28 (6) ◽

pp. 313-318 ◽

Cited By ~ 7

Author(s):

Priscila Zlotowski ◽

André M.R. Corrêa ◽

David E.S.N. Barcellos ◽

Cláudio E.F. Cruz ◽

William Asanome ◽

...

Keyword(s):

Lymph Nodes ◽

Villous Atrophy ◽

Clinical Signs ◽

Postweaning Multisystemic Wasting Syndrome ◽

Porcine Circovirus ◽

Mesenteric Lymph Nodes ◽

Salmonella Spp ◽

Wasting Syndrome ◽

Mesenteric Lymph ◽

Intestinal Lesions

Samples of mesenteric lymph nodes and intestines from 79 unthrifty 3- to 5-month-old postweaning pigs, confirmed as naturally affected with postweaning multisystemic wasting syndrome (PMWS), were studied. Pigs originated from 12 farms in southern Brazil and were selected on the basis of clinical signs and/or gross lesions suggestive of enteric disorder. Lymphohistiocytic infiltrates of varying intensity were associated with anti-porcine circovirus type 2 (anti-PCV2) immunostaining (IS) in samples of intestines and mesenteric lymph nodes from all pigs. Although most findings were similar to those described in PCV2-associated enteritis, anti-PCV2 IS in association with depletion of the goblet cell mucin stores (24 pigs), diffuse ileal villous atrophy and fusion (18 pigs), and dilatation of the lymphatic vessels (11 pigs) combined or not with lymphangitis were also observed. PCV2 antigen was immunohistochemically demonstrated in the cytoplasm and nuclei from intralesional epithelial cells, histiocytes, and endothelial-like cells in intestinal tissues. Together these findings imply an association with PCV2. The presence of co-infections by Lawsonia intracellularis, Brachyspira spp., Mycobacterium spp., Salmonella spp., rotavirus, parvovirus, coronavirus and enteric calicivirus with PCV2 in the intestinal lesions was investigated.

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Prevalence and antimicrobial susceptibility of salmonella species isolate from slaughtered cows in Iraq

The Iraqi Journal of Veterinary Medicine ◽

10.30539/iraqijvm.v37i1.339 ◽

2013 ◽

Vol 37 (1) ◽

pp. 96-101

Author(s):

Afaf Abdulrahman Yousif

Keyword(s):

Antimicrobial Susceptibility ◽

Brilliant Green ◽

Diagnostic Study ◽

Mesenteric Lymph Nodes ◽

Biochemical Tests ◽

Salmonella Spp ◽

Antimicrobial Drugs ◽

Antibiotic Susceptibility Pattern ◽

Central Public Health ◽

Mesenteric Lymph

This study was planned to determine the prevalence and antimicrobial susceptibility of Salmonella spp. One hundred bovine with different age and both sexes at slaughterhouse were examined. Four hundred samples were collected from different internal organ (bile, Liver, spleen and mesenteric lymph nodes). Diagnostic study depended upon the morphological and cultural properties of the isolates on some selective media like Brilliant green, XLD, SS agar which used in addition to different biochemical tests, API-20E )Enterobacteriaceae Identification Kit.). Isolates were serotyped at the Central Public Health Laboratories (National Center of Salmonellae in Baghdad, Iraq). Eleven isolates consisting of Salmonella anatum (9.09%), S.newport (27.27%), S.enteritidis (45.45 %) and S.ohio (18.18%). The percentage of infection were 3% in the mesenteric lymph node and liver, (4%) in bile, and (1%) in spleen. The antibiotic susceptibility pattern of Salmonella against 15 antimicrobial drugs revealed that all isolates were sensitive (100%) to ciprofloxacin and amicacin. And most of isolates were resistance to cloxacillin, cefixime, amoxicillin. and gave intermediate results to neomycin, gentamycin, tetracycline and streptomycin.

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Effect of the addition of protected sodium butyrate to the feed on Salmonella spp. infection dynamics in fattening pigs

Animal Feed Science and Technology ◽

10.1016/j.anifeedsci.2017.06.008 ◽

2017 ◽

Vol 231 ◽

pp. 12-18 ◽

Cited By ~ 5

Author(s):

Alejandro Casanova-Higes ◽

Sara Andrés-Barranco ◽

Raúl C. Mainar-Jaime

Keyword(s):

Sodium Butyrate ◽

Salmonella Spp ◽

Infection Dynamics ◽

Fattening Pigs

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Distribution of Salmonella Strains in Farrow-to-Finish Pig Herds: A Longitudinal Study

Journal of Food Protection ◽

10.4315/0362-028x-68.10.2012 ◽

2005 ◽

Vol 68 (10) ◽

pp. 2012-2021 ◽

Cited By ~ 23

Author(s):

NATHALIE NOLLET ◽

KURT HOUF ◽

JEROEN DEWULF ◽

LUC DUCHATEAU ◽

LIEVEN DE ZUTTER ◽

...

Keyword(s):

Random Amplified Polymorphic Dna ◽

Production Cycle ◽

Finishing Pigs ◽

Direct Transmission ◽

Mesenteric Lymph Nodes ◽

Indirect Transmission ◽

Mesenteric Lymph ◽

Horizontal Spread ◽

Fattening Pigs

The aims of this study were to investigate patterns of Salmonella shedding in finishing pigs and to study the role of the sow in the transmission of Salmonella to her offspring. In each of the three herds (A, B, and C), one cohort of sows (n = 34, n = 40, n = 32, respectively) together with three piglets of their offspring (n = 102, n = 120, n = 96, respectively) were selected. Individual fecal and blood samples were taken from the sows at different times during one production cycle and from the piglets from weaning until slaughter. At slaughter, contents from the jejunum, colon, and mesenteric lymph nodes were collected. Fecal samples, as well as the jejunum, colon, and mesenteric lymph node samples collected at slaughter, were submitted to a qualitative Salmonella analysis. Isolates were characterized by random amplified polymorphic DNA, and if necessary, further characterization was done by pulsed-field gel electrophoresis. In herds A and B, Salmonella shedding began in the nursery. A significant increase in the number of Salmonella shedders was seen after transferring pigs to the growing unit in herd B (P = 0.003) and to the finishing unit in herds A (P < 0.001) and B (P = 0.013). None of the fattening pigs in herd C were shedding Salmonella. This study reveals that transferring pigs is an important trigger to induce Salmonella shedding, leading to horizontal spread. Direct transmission of Salmonella from the sows to their piglets could not be demonstrated, but the similarities between the isolates found in the sows and those found during the nursery and finishing periods and at slaughter suggested indirect transmission.

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