scholarly journals Polyarteritis nodosa presenting with frank hematuria

2013 ◽  
Vol 4 (6) ◽  
pp. 172
Author(s):  
Muhammad Shabi Ahmad ◽  
Aninda Saha ◽  
David Reaich ◽  
Geoffery P. Naisby ◽  
Alaiyi Fred West

Polyarteritis nodosa (PAN) is an uncommon systemic vasculitischaracterized by necrotizing inflammation of small- or mediumsizedarteries. The disease normally presents with non-specificsymptoms. Urological symptoms at presentation are extremely rare.We report a 65-year-old man who was diagnosed with a polyarteritisnodosa having presented atypically with left testicular pain andswelling, and an intratesticular lesion. He developed painless visiblehematuria while under investigation. No gross arterio-venousfistula was seen to suggest a false aneurysm. Subsequently, laboratorystudies showed positive anti-neutrophil cytoplasmic antibodylevels and a raised erythrocyte sedimentation rate. This was anunusual presentation of PAN diagnosed with multidisciplinaryinput from the urology, radiology and nephrology teams.

Author(s):  
Thomas E. Feasby ◽  
Gary G. Ferguson ◽  
J.C.E. Kaufmann

SUMMARY:This patient presented as a subacute progressive cervical myelopathy and the differential diagnosis included cervical spondylotic myelopathy and intramedullary mass. Microscopically, vascular lesions plus a patchy myelomalacia indicated a vasculitis. However, there was no suggestion of a generalized vasculitis at autopsy and the only supporting laboratory study was a raised erythrocyte sedimentation rate. It would seem that a vasculitis similar to polyarteritis nodosa or other collagen disease may be confined to the spinal cord.


2008 ◽  
Vol 24 (5) ◽  
pp. 351
Author(s):  
Young Ki Kim ◽  
Seong Woo Hong ◽  
Jung Woo Chun ◽  
Yeo Goo Chang ◽  
In Wook Paik ◽  
...  

2021 ◽  
pp. 1-7
Author(s):  
Zahra Soleimani ◽  
Fatemeh Amighi ◽  
Zarichehr Vakili ◽  
Mansooreh Momen-Heravi ◽  
Seyyed Alireza Moravveji

BACKGROUND: The diagnosis of osteomyelitis is a key step of diabetic foot management. Procalcitonin (PCT) is a novel infection marker. This study aimed to investigate the diagnostic value of procalcitonin and other conventional infection markers and clinical findings in diagnosis of osteomyelitis in diabetic foot patients. METHODS AND MATERIALS: This diagnostic value study was carried out on ninety patients with diabetic infected foot ulcers admitted in Kashan Beheshti Hospital, 2016. After obtaining consent, 10 cc blood sample was taken for measuring serum PCT, CBC, ESR, CRP and FBS. Clinical characteristics of the wounds were noted. Magnetic resonance imaging of the foot was performed in all patients to diagnose osteomyelitis. All statistical analyses were done with the use of SPSS-16. RESULTS: PCT levels were 0.13 ± 0.02 ng/mili patients with osteomyelitis (n= 45) and 0.04 ± 0.02 ng/ml in patients without osteomyelitis (n= 45). PCT, Erythrocyte sedimentation rate and C-reactive protein was found significantly higher in patients with osteomyelitis (p< 0.001). The ROC curve was calculated for PCT. The area under the ROC curve for infection identification was 1 (p< 0.001). The best cut-off value for PCT was 0.085 ng/ml. Sensitivity, specificity, and positive and negative predictive values were 100%, 97.8%,97.8% and 100%, respectively. CONCLUSION: In this group of patients, PCT was useful to discriminate patients with bone infection. Also, Erythrocyte sedimentation rate and C-reactive protein can be used as a marker of osteomyelitis in diabetic patients.


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