scholarly journals Comparison of Bulk and Precipitation Polymerization Method of Synthesis Molecular Imprinted Solid Phase Extraction for Atenolol using Methacrylic Acid

2018 ◽  
Vol 11 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Rimadani Pratiwi ◽  
Sandra Megantara ◽  
Driyanti Rahayu ◽  
Indraswari Pitaloka ◽  
Aliya Nur Hasanah
Keyword(s):  
Solid Phase Extraction ◽  
Methacrylic Acid ◽  
Solid Phase ◽  
Precipitation Polymerization ◽  
Phase Extraction ◽  
Polymerization Method

scholarly journals Molecular Imprinted Polymer for Ethylmorphine with Methacrylic Acid and Acrylamide as Functional Monomer in Butanol Using Two Polymerization Method

2020 ◽  
Vol 10 (3) ◽  
pp. 277-288
Author(s):  
Aliya Nur Hasanah ◽  
Diane Fauzi ◽  
Beska Zausha Witka ◽  
Driyanti Rahayu ◽  
Rimadani Pratiwi
Keyword(s):  
Solid Phase Extraction ◽  
Methacrylic Acid ◽  
Solid Phase ◽  
Bulk Polymerization ◽  
Degree Of Polymerization ◽  
Precipitation Polymerization ◽  
Therapeutic Effects ◽  
Phase Extraction ◽  
Functional Monomer ◽  
Polymerization Method

Ethylmorphine is an opioid that has therapeutic effects as narcotic analgesic and antitussive, which has low levels and can be misused. Hence, it is crucial to monitor by analyze the levels of ethylmorphine in blood selectively. The preparation method that can be used to extract ethylmorphine from the sample is using molecular imprinting solid-phase extraction (MI-SPE) due to its sensitivity and selectivity. This study aims to compare the result of synthesis using two different polymerization methods, and also to examine the analytical performance and characteristics of imprinted polymers from two distinct functional monomers: methacrylic acid (MAA) and acrylamide (AM). The stages of this study include the determination of association constants, synthesis of polymer MI-SPE ethylmorphine using bulk and precipitation polymerization method, extracted template from the polymer, and determined the adsorption ability, capacity, and selectivity of the polymer. MI-SPE that has been made then characterized by using Fourier-Transform Infrared (FTIR) and Scanning Electron Microscope (SEM). The results showed that MIP with acrylamide (MIP-AM) as functional monomer and made by precipitation polymerization had better analytic performances than MIP that made by bulk polymerization, with affinity value 0.072 mg/g and homogeneity value -0.77. It is also selective toward ethylmorphine with imprinting factor value 27.43. In addition, the result of characterization using FTIR and SEM showed that MIP-AM 2, MIP-MAA 1, and MIP-MAA 2 might have a low degree of polymerization due to the presence of vinyl peaks, besides MIP-AM 2 and MIP-MAA 2 had smaller particle size than the NIP with an average value of 0,31 ± 0,21 mm and 0.28 ± 0.05 mm. Based on the result of this study, MIP-AM made by precipitation polymerization could be used to extract ethylmorphine on solid-phase extraction.

Application of molecularly imprinted polymers for the solid-phase extraction of hexanitrohexaazaisowurtzitane (CL-20) from soil samples

2016 ◽  
Vol 8 (22) ◽  
pp. 4413-4420 ◽  
Author(s):  
Jian Wang ◽  
Min Xue ◽  
Zihui Meng ◽  
Zhibin Xu ◽  
Jun Luo
Keyword(s):  
Solid Phase Extraction ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Precipitation Polymerization ◽  
Soil Samples ◽  
Phase Extraction ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

Eight molecularly imprinted polymers (MIPs) for CL-20 were synthesized by precipitation polymerization in acetonitrile.

Enhanced solid phase extraction of DNA using hydrophilic monodisperse poly(methacrylic acid-co-ethylene dimethacrylate) microparticles

2019 ◽  
Vol 46 (3) ◽  
pp. 3063-3072
Author(s):  
Petr Šálek ◽  
Marcela Filipová ◽  
Daniel Horák ◽  
Vladimír Proks ◽  
Olga Janoušková
Keyword(s):  
Solid Phase Extraction ◽  
Methacrylic Acid ◽  
Solid Phase ◽  
Phase Extraction ◽  
Ethylene Dimethacrylate

scholarly journals Application of Molecular Imprinted Polymers for Selective Solid Phase Extraction of Bisphenol A

2016 ◽  
Vol 23 (4) ◽  
pp. 651-664 ◽  
Author(s):  
Anna Poliwoda ◽  
Małgorzata Mościpan ◽  
Piotr P. Wieczorek
Keyword(s):  
Bisphenol A ◽  
Solid Phase Extraction ◽  
Methacrylic Acid ◽  
Solid Phase ◽  
Selective Extraction ◽  
Phase Extraction ◽  
Aqueous Samples ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Relative Standard

Abstract Selective molecularly imprinted polymers (MIPs) with bisphenol A as template were synthesized using the non-covalent imprinting approach. MIPs were prepared using thermally initiated polymerization with 1,1’-azobis(cyclohexanecarbonitryle) (ACHN) as initiator and ethylene glycol dimethacrylate (EDMA) as a cross-linking agent. The tested functional monomers included methacrylic acid, acrylamide, and 4-vinylpyridine. The selectivity of the BPA-MIP for the solid phase extraction of bisphenol A was tested in samples containing other related alkylphenols. The polymers prepared in acetonitrile using methacrylic acid or acrylamide as monomer showed the highest selectivity towards target analyte (the selectivity ratio 8:1, respectively for MIP and NIP). The proposed procedure has been proven to be an effective for selective extraction of bisphenol A in aqueous samples (recoveries over 85%) enabling detection and quantification limits of 25 and 70 μg/dm3, respectively based on 10 cm3 of sample volume, with relative standard deviations (RSD) lower than 6%. The obtained molecularly imprinted material showed interesting properties for selective extraction and preconcentration of studied analyte from large volumes of aqueous samples without any problems of cartridge clogging.

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