scholarly journals Prevalence of the inappropriate sinus tachycardia and comparison of the heart rate variability characteristics with propensity score matched control group

Author(s):  
Evrim Şimşek
1997 ◽  
Vol 78 (5) ◽  
pp. 363-366
Author(s):  
S. P. Popov ◽  
V. S. Gorin ◽  
E. V. Khristenko

The labor characteristics and contractile activity of the uterus resulting from programmed labors after the intracervical application of gel with prostaglandin E2 are studied. The gel with prostaglandin E2 was not used in the matched control group of patients with programmed labors. After introduction of the gel the modified Bishop scores significantly improved, the labor began in one of the patients. During introduction of the gel the hypertonus of the uterus or the pathology of the fetus heart rate is not observed. The length of the active phase and the second period of the labor is significantly shorter than in the control group. The contractile activity of the uterus is similar in both groups. The primary cervical effect of the gel is supposed.


1998 ◽  
Vol 82 (4) ◽  
pp. 531-534 ◽  
Author(s):  
Agustin Castellanos ◽  
Federico Moleiro ◽  
Simon Chakko ◽  
Helbert Acosta ◽  
Heikki Huikuri ◽  
...  

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Júlia Aranyó ◽  
Victor Bazan ◽  
Gemma Lladós ◽  
Maria Jesús Dominguez ◽  
Felipe Bisbal ◽  
...  

AbstractInappropriate sinus tachycardia (IST) is a common observation in patients with post-COVID-19 syndrome (PCS) but has not yet been fully described to date. To investigate the prevalence and the mechanisms underlying IST in a prospective population of PCS patients. Consecutive patients admitted to the PCS Unit between June and December 2020 with a resting sinus rhythm rate ≥ 100 bpm were prospectively enrolled in this study and further examined by an orthostatic test, 2D echocardiography, 24-h ECG monitoring (heart rate variability was a surrogate for cardiac autonomic activity), quality-of-life and exercise capacity testing, and blood sampling. To assess cardiac autonomic function, a 2:1:1 comparative sub-analysis was conducted against both fully recovered patients with previous SARS-CoV-2 infection and individuals without prior SARS-CoV-2 infection. Among 200 PCS patients, 40 (20%) fulfilled the diagnostic criteria for IST (average age of 40.1 ± 10 years, 85% women, 83% mild COVID-19). No underlying structural heart disease, pro-inflammatory state, myocyte injury, or hypoxia were identified. IST was accompanied by a decrease in most heart rate variability parameters, especially those related to cardiovagal tone: pNN50 (cases 3.2 ± 3 vs. recovered 10.5 ± 8 vs. non-infected 17.3 ± 10; p < 0.001) and HF band (246 ± 179 vs. 463 ± 295 vs. 1048 ± 570, respectively; p < 0.001). IST is prevalent condition among PCS patients. Cardiac autonomic nervous system imbalance with decreased parasympathetic activity may explain this phenomenon.


Author(s):  
Lou M. Almskog ◽  
Ulf Hammar ◽  
Agneta Wikman ◽  
Anders Östlund ◽  
Jonas Svensson ◽  
...  

Abstract Background Fibrinogen concentrate (FC) is frequently used to treat bleeding trauma patients, although the clinical effects are not well known. In this study we describe demographic and clinical outcome data in a cohort of trauma patients receiving FC, compared to a matched control group, who did not receive FC. Methods This retrospective, single-center, observational study included adult trauma patients admitted to a level 1-trauma center in Sweden between January 2013 and June 2015. The study population consisted of patients to whom FC was administrated within 24 h (n = 138, “Fib+”). Patients with Injury Severity Score (ISS) > 49 and/or deceased within 1 h from arrival were excluded (n = 30). Controls (n = 108) were matched for age, gender and ISS (“Fib-“). Primary outcome was mortality (24 h−/30 days−/1 year-), and secondary outcomes were blood transfusions, thromboembolic events and organ failure. Results The Fib+ group, despite having similar ISS as Fib-, had higher prevalence of penetrating trauma and lower Glasgow Coma Scale (GCS), indicating more severe injuries. Patients receiving FC had a higher mortality after 24 h/ 30 days/ 1 year compared to controls (Fib-). However, in a propensity score matched model, the differences in mortality between Fib+ and Fib- were no longer significant. Blood transfusions were more common in the Fib+ group, but no difference was observed in thromboembolic events or organ failure. In both groups, low as well as high P-fibrinogen levels at arrival were associated with increased mortality, with the lowest mortality observed at P-fibrinogen values of 2–3 g/l. Conclusions Despite equal ISS, patients receiving FC had a higher mortality compared to the control group, presumably associated to the fact that these patients were bleeding and physiologically deranged on arrival. When applying a propensity score matching approach, the difference in mortality between the groups was no longer significant. No differences were observed between the groups regarding thromboembolic events or organ failure, despite higher transfusion volumes in patients receiving FC.


1998 ◽  
Vol 31 ◽  
pp. 169-170
Author(s):  
I.G. Maia ◽  
F.E.S. Cruz ◽  
M. Fagundes ◽  
R. Sá ◽  
S. Boghossian ◽  
...  

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