scholarly journals Longitudinal Association of Arterial Stiffness and Pressure Wave Reflection with Decline of the Cardiac Systolic Performance in Healthy Men

2021 ◽  
Author(s):  
Kento Kumai ◽  
Hirofumi Tomiyama ◽  
Takamichi Takahashi ◽  
Hiroki Nakano ◽  
Masatsune Fujii ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Pressure Wave ◽  
Wave Reflection ◽  
Healthy Men ◽  
Systolic Performance ◽  
Longitudinal Association

Abstract P057: Arterial Stiffness And Pressure Wave Reflection In The Development Of Isolated Diastolic Hypertension

Hypertension ◽  
2020 ◽  
Vol 76 (Suppl_1) ◽  
Author(s):  
Hirofumi Tomiyama ◽  
Kazuki N Shiina ◽  
Taishiro Chikamori ◽  
Akira Yamashina
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Pressure Wave ◽  
Wave Reflection ◽  
Augmentation Index ◽  
Care Center ◽  
Estimating Equation ◽  
Health Care Center ◽  
Diastolic Hypertension ◽  
New Onset

Importance: While increased arterial stiffness and augmented pressure wave reflection are thought to be key factors in the development of systolic/diastolic hypertension (SDHT) or isolated systolic hypertension (ISHT) via the elevation of systolic blood pressure, their associations with the development of isolated diastolic hypertension (IDHT) have not been clarified. Objective: To examine the significance of augmented pressure wave reflection in the absence of accompanying increase of the arterial stiffness in the development of IDHT. Design and Setting: The prospective observational study conducted in the employees of a Japanese construction company at its health care center from year 2007 through year 2015 with a mean follow-up of 6.4 years, respectively. Participants: A total of 3022 Japanese male employees without hypertension at the start of this study. Main Outcomes and Measures: The annual assessment of prevalence of any phenotypes of hypertension. The blood pressure, brachial-ankle pulse wave velocity (baPWV), and radial augmentation index (rAI) were measured annually during the study period. Results: At the end of the study period, 129 subjects were diagnosed as having SDHT, 112 as having ISHT, and 74 as having IDHT. Both the baPWV and rAI showed significant individual odds ratios for new onset of SDHT and new onset of ISHT. However, only rAI, but not the brachial-ankle PWV, showed a significant odds ratio (1.44, P<0.01) for new onset of IDHT. This association was significant in subjects without elevated baPWV values at the start of the study (i.e., baPWV < 1224 cm/sec), but not in those with elevated brachial-ankle PWV at the start of the study. Generalized estimating equation analyses demonstrated a significant longitudinal association of the rAI, but not baPWV, with the prevalence of IDHT (estimate = 0.02, P=0.02). Conclusions: While increased arterial stiffness and augmented pressure wave reflection present concomitantly may be associated with the development of SDHT and ISHT, augmented pressure wave reflection alone, which may be related to isolated peripheral vascular damage, in the absence of accompanying increase of the arterial stiffness, may be a significant factor in the development of IDHT.

Progressive Resistance Training Without Volume Increases Does Not Alter Arterial Stiffness and Aortic Wave Reflection

2007 ◽  
Vol 232 (9) ◽  
pp. 1228-1235 ◽  
Author(s):  
Darren P. Casey ◽  
Darren T. Beck ◽  
Randy W. Braith
Keyword(s):  
Resistance Training ◽  
Arterial Stiffness ◽  
Pressure Wave ◽  
Wave Reflection ◽  
Augmentation Index ◽  
Aortic Pressure ◽  
Control Group ◽  
Training Volume ◽  
Leg Extension ◽  
Peripheral Arterial

Endurance exercise is efficacious in reducing arterial stiffness. However, the effect of resistance training (RT) on arterial stiffening is controversial. High-intensity, high-volume RT has been shown to increase arterial stiffness in young adults. We tested the hypothesis that an RT protocol consisting of progressively higher intensity without concurrent increases in training volume would not elicit increases in either central or peripheral arterial stiffness or alter aortic pressure wave reflection in young men and women. The RT group ( n = 24; 21 ± 1 years) performed two sets of 8–12 repetitions to volitional fatigue on seven exercise machines on 3 days/week for 12 weeks, whereas the control group ( n = 18; 22 ± 1 years) did not perform RT. Central and peripheral arterial pulse wave velocity (PWV), aortic pressure wave reflection (augmentation index; AIx), brachial flow–mediated dilation (FMD), and plasma levels of nitrate/nitrite (NOx) and norepinephrine (NE) were measured before and after RT. RT increased the one-repetition maximum for the chest press and the leg extension ( P < 0.001). RT also increased lean body mass ( P < 0.01) and reduced body fat (%; P < 0.01). However, RT did not affect carotid-radial, carotid-femoral, and femoral-distal PWV (8.4 ± 0.2 vs. 8.0 ± 0.2 m/sec; 6.5 ± 0.1 vs. 6.3 ± 0.2 m/sec; 9.5 ± 0.3 vs. 9.5 ± 0.3 m/sec, respectively) or AIx (2.5% ± 2.3% vs. 4.8% ± 1.8 %, respectively). Additionally, no changes were observed in brachial FMD, NOx, NE, or blood pressures. These results suggest that an RT protocol consisting of progressively higher intensity without concurrent increases in training volume does not increase central or peripheral arterial stiffness or alter aortic pressure wave characteristics in young subjects.

4.3 ABNORMAL PRESSURE WAVE REFLECTION ACCELERATES THE DEVELOPMENT OF HYPERTENSION VIA THE INCREASE OF ARTERIAL STIFFNESS

2017 ◽  
Vol 20 (C) ◽  
pp. 56
Author(s):  
Hirofumi Tomiyama ◽  
Akira Yamashina ◽  
Shunsuke Komatsu ◽  
Kazuki Shiina ◽  
Chisa Matsumoto ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Pressure Wave ◽  
Wave Reflection ◽  
Abnormal Pressure

scholarly journals Changes in Arterial Stiffness and Wave Reflection With Advancing Age in Healthy Men and Women

Hypertension ◽  
2004 ◽  
Vol 43 (6) ◽  
pp. 1239-1245 ◽  
Author(s):  
Gary F. Mitchell ◽  
Helen Parise ◽  
Emelia J. Benjamin ◽  
Martin G. Larson ◽  
Michelle J. Keyes ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Wave Reflection ◽  
Men And Women ◽  
Healthy Men

scholarly journals Total Sleep Deprivation Does Not Adversely Affect Arterial Stiffness, Wave Reflection and Aortic Pressure in Young Healthy Men

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Stephanie Lapierre ◽  
Brady J Holmer ◽  
Jisok Lim ◽  
Yasemin Sakarya ◽  
William New ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Sleep Deprivation ◽  
Wave Reflection ◽  
Aortic Pressure ◽  
Healthy Men ◽  
Total Sleep Deprivation

Sarcopenic obesity and arterial stiffness, pressure wave reflection and central pulse pressure: The J-SHIPP study

2014 ◽  
Vol 174 (1) ◽  
pp. 214-217 ◽  
Author(s):  
Maya Ohara ◽  
Katsuhiko Kohara ◽  
Yasuharu Tabara ◽  
Masayuki Ochi ◽  
Tokihisa Nagai ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Pulse Pressure ◽  
Pressure Wave ◽  
Wave Reflection ◽  
Sarcopenic Obesity ◽  
Central Pulse Pressure

Abstract P514: Age-related Differences in the Annual Changes of the Ankle-brachial Pressure Index: Underlying Mechanisms

Hypertension ◽  
2017 ◽  
Vol 70 (suppl_1) ◽  
Author(s):  
Shogen Fujii ◽  
Kazuki Shiina ◽  
Taishiro Chikamori ◽  
Akira yamashina ◽  
Chisa Matsumoto ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Pressure Wave ◽  
Wave Reflection ◽  
Ankle Brachial Pressure Index ◽  
Middle Aged ◽  
Japanese Men ◽  
Annual Increase ◽  
Pressure Index ◽  
Age Related ◽  
Annual Changes

Objectives: The present prospective observational study was conducted to examine the age-related annual changes of the ankle-brachial pressure index (ABI) and their association with the longitudinal changes of the brachial-ankle pulse wave velocity (baPWV), a marker of arterial stiffness, and the radial augmentation index (rAI), a marker of the pressure wave reflection in middle-aged Japanese men. Methods and Results: In 4264 men (42 ± 9 years old) of a Japanese construction company, the ABI, baPWV and rAI were measured annually over a 9-year observation period. During the study period, ABI (from 1.10 ± 0.07 to 1.13 ± 0.07), baPWV (from 1295 ± 194 to 1344 ± 217 cm/sec) and rAI (from 69 ± 13 to 72 ± 13 %) were increased significantly (p<0.01). Mixed model linear regression analysis of the repeated-measures data revealed that the annual increase of the ABI was lower in men aged over 50 years of age (n = 1237: 0.28 ± 0.06) than in those aged under 50 years of age (n = 3027: 0.50 ± 0.04) (p < 0.01). Furthermore, while increased baPWV (estimate = 0.017, p < 0.05) and increased rAI (estimate 0.254, p < 0.05) were significantly related to the annual increase of the ABI in men aged <50 years (p < 0.01), no such association was observed in men aged > 50 years. Conclusion: In middle-aged Japanese men, the ABI increases with age until the age of 50 years, and increased arterial stiffness and increased pressure wave reflection may contribute to this annual increase. In men aged > 50 years, the annual increase of the ABI was attenuated, which could be related, at least in part, to the attenuation of the increase of the pressure wave reflection and also attenuation of the effect of increased arterial stiffness on the hydrostatic pressure in the arteries with age. These findings may suggest the usefulness of ABI measurement as a screening tool for peripheral arterial disease in men over 50 years old.

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